UniProtKB - Q32NQ8 (RNF10_XENLA)
Protein
RING finger protein 10
Gene
rnf10
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
May act as a transcriptional factor participating in nerve development and Schawnn cell differentiation.By similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 206 – 248 | RING-typePROSITE-ProRule annotationAdd BLAST | 43 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- transcription regulatory region sequence-specific DNA binding Source: UniProtKB
GO - Biological processi
- negative regulation of Schwann cell proliferation Source: UniProtKB
- positive regulation of myelination Source: UniProtKB
- positive regulation of transcription by RNA polymerase II Source: UniProtKB
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: RING finger protein 10 |
Gene namesi | Name:rnf10 |
Organismi | Xenopus laevis (African clawed frog) |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-866563, rnf10.S |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000259588 | 1 – 756 | RING finger protein 10Add BLAST | 756 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 592685, 1 interactor |
IntActi | Q32NQ8, 1 interactor |
Family & Domainsi
Sequence similaritiesi
Belongs to the RNF10 family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 206 – 248 | RING-typePROSITE-ProRule annotationAdd BLAST | 43 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
OMAi | SYNKEQF |
OrthoDBi | 1373540at2759 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR039739, Mag2/Rnf10 IPR018957, Znf_C3HC4_RING-type IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
PANTHERi | PTHR12983, PTHR12983, 1 hit |
Pfami | View protein in Pfam PF00097, zf-C3HC4, 1 hit |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q32NQ8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPLSSQGSPA DMDPGSANTN KNQNRSGSAG PSGESKPKSE QKNGSGSKQR
60 70 80 90 100
YNRKRENSYP KNETLAGQTR RSCPQKSKTF NKVPPQRGGN KQYGMGRREE
110 120 130 140 150
VAETQRAEFS SAEYSGPKKI NLNHLLNFTF ESRGHPGGPH SANGHFGRRH
160 170 180 190 200
KWANKPFNKE LFLQANCQFV VSDVNDYSVH FTDPDTLVSW DFVEQVRIFS
210 220 230 240 250
HEVASCPICL YPPVAAKITR CGHIFCWPCI LHYLSLSEKD WSRCPICYSS
260 270 280 290 300
IIKKDLKSVV ATETHLYSVG DKITMQLMRR EKGVLVAMPK SKWMKLDEPI
310 320 330 340 350
HMGDLDHIQY SKLLLASWEQ ILNYVIAEEK FALFEQYNAE KETPEACFIE
360 370 380 390 400
AAIQELQDRA ESLCTASKPE IEAATLSMKT LNFEATCDKP NTVMEKEVVH
410 420 430 440 450
YISAFEEETM EPPCEDCSPT ESPPPDIPAV LETEENTVTD GVLPLLSQPE
460 470 480 490 500
SKPKNDEPLA NSHYYYFYQA VDGQHVYLHP VNVRCLVHEY GSLERCPEKI
510 520 530 540 550
TATVVEMDGF TMTEEVRRRH RYLCHLPLTC EFSICEIALG PPDVSVKTLE
560 570 580 590 600
LFTEEVEKRK RLRQRKARDE QRREKRIEIE ENRKQGKYPE AYIALENFQQ
610 620 630 640 650
FPAFSSSPVY SLSSVETQNF VSISPVSCSP TSQSGSLLGA ECSLDPSFTE
660 670 680 690 700
DESRCPSFAQ MLRAGKAKPE TWPKAAHKNV AENTLTPATA DSDGESDCSE
710 720 730 740 750
RVPVPSFQNS FSQAMEAAFL KLDTALPTPP SSVEKGGRRK KKQQKLLFST
SIVHTK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC108524 mRNA Translation: AAI08525.1 |
RefSeqi | NP_001089838.1, NM_001096369.1 |
Genome annotation databases
GeneIDi | 734904 |
KEGGi | xla:734904 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC108524 mRNA Translation: AAI08525.1 |
RefSeqi | NP_001089838.1, NM_001096369.1 |
3D structure databases
SMRi | Q32NQ8 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 592685, 1 interactor |
IntActi | Q32NQ8, 1 interactor |
Genome annotation databases
GeneIDi | 734904 |
KEGGi | xla:734904 |
Organism-specific databases
CTDi | 734904 |
Xenbasei | XB-GENE-866563, rnf10.S |
Phylogenomic databases
OMAi | SYNKEQF |
OrthoDBi | 1373540at2759 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR039739, Mag2/Rnf10 IPR018957, Znf_C3HC4_RING-type IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
PANTHERi | PTHR12983, PTHR12983, 1 hit |
Pfami | View protein in Pfam PF00097, zf-C3HC4, 1 hit |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
PROSITEi | View protein in PROSITE PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RNF10_XENLA | |
Accessioni | Q32NQ8Primary (citable) accession number: Q32NQ8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | December 6, 2005 | |
Last modified: | December 2, 2020 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |