Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 96 (31 Jul 2019)
Sequence version 2 (15 Jan 2008)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Protein FAM214A

Gene

FAM214A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM214A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM214A
Synonyms:KIAA1370
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25609 FAM214A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q32MH5

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000047346

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671609

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM214A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
166218826

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003156131 – 1076Protein FAM214AAdd BLAST1076

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q32MH5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q32MH5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q32MH5

PeptideAtlas

More...
PeptideAtlasi
Q32MH5

PRoteomics IDEntifications database

More...
PRIDEi
Q32MH5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
61600 [Q32MH5-1]
61601 [Q32MH5-2]
61602 [Q32MH5-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q32MH5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q32MH5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000047346 Expressed in 202 organ(s), highest expression level in small intestine Peyer's patch

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q32MH5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q32MH5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039369
HPA040180

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121108, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q32MH5, 9 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000443598

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q32MH5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM214 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2306 Eukaryota
ENOG41115V6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157573

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113164

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q32MH5

Identification of Orthologs from Complete Genome Data

More...
OMAi
VPSKVFR

Database of Orthologous Groups

More...
OrthoDBi
383904at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q32MH5

TreeFam database of animal gene trees

More...
TreeFami
TF325496

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025261 DUF4210
IPR033473 FAM214/SPAC3H8.04_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13889 Chromosome_seg, 1 hit
PF13915 DUF4210, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01177 DUF4210, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q32MH5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKPDRDTLDE YFEYDAEEFL VSLALLITEG RTPECSVKGR TESFHCPPAQ
60 70 80 90 100
SCYPVTTKHE CSDKLAQCRQ ARRTRSEVTL LWKNNLPIMV EMMLLPDCCY
110 120 130 140 150
SDDGPTTEGI DLNDPAIKQD ALLLERWILE PVPRQNGDRF IEEKTLLLAV
160 170 180 190 200
RSFVFFSQLS AWLSVSHGAI PRNILYRISA ADVDLQWNFS QTPIEHVFPV
210 220 230 240 250
PNVSHNVALK VSVQSLPRQS NYPVLTCSIH TNIGLYEKRI QQHKLKTHQH
260 270 280 290 300
HNPNEAEQCG TNSSQRLCSK QTWTMAPESV LHAKSGPSPE YTAAVKNIKL
310 320 330 340 350
YPGTGSKSDH GTSQANILGF SGIGDIKSQE TSVRTLKSFS MVDSSISNRQ
360 370 380 390 400
SFWQSAGETN PLIGSLIQER QEIIARIAQH LIHCDPSTSH VSGRPFNTQE
410 420 430 440 450
SSSLHSKLFR VSQENENVGK GKEAFSMTFG SPEFSSPEDT NEGKIRLKPE
460 470 480 490 500
TPRSETCISN DFYSHMPVGE TNPLIGSLLQ ERQDVIARIA QHLEHIDPTA
510 520 530 540 550
SHIPRQSFNM HDSSSVASKV FRSSYEDKNL LKKNKDESSV SISHTKCSLL
560 570 580 590 600
GDISDGKNLV PNKCFTSFKN NSKEKCSLKH QTRNQCQNNP SEIIQSTYQE
610 620 630 640 650
TQNKSSSLST SSILSQHKEN NLDLTSRFKE QEMSNGIDKQ YSNCTTIDKQ
660 670 680 690 700
ICTNKYKEKI INENYNPKFF GNLQSDDSKK NDSKIKVTVL EMSEYLNKYE
710 720 730 740 750
SMSSNKDSKR PKTCEQNTQL NSIENYLNKD NEGFKCKKSD QLKNEQDKQE
760 770 780 790 800
DPTNEKSQNY SQRRSIKDCL STCEQPKNTE VLRTTLKHSN VWRKHNFHSL
810 820 830 840 850
DGTSTRAFHP QTGLPLLSSP VPQRKTQSGC FDLDSSLLHL KSFSSRSPRP
860 870 880 890 900
CLNIEDDPDI HEKPFLSSSA PPITSLSLLG NFEESVLNYR FDPLGIVDGF
910 920 930 940 950
TAEVGASGAF CPTHLTLPVE VSFYSVSDDN APSPYMGVIT LESLGKRGYR
960 970 980 990 1000
VPPSGTIQVT LFNPNKTVVK MFVVIYDLRD MPANHQTFLR QRTFSVPVKQ
1010 1020 1030 1040 1050
EVKRSVNKEN IRHTEERLLR YLIHLRFQSS KSGKIYLHRD VRLLFSRKSM
1060 1070
EVDSGAAYEL KSYTESPTNP QFSPRC
Length:1,076
Mass (Da):121,670
Last modified:January 15, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i304B1C93DB92B18E
GO
Isoform 2 (identifier: Q32MH5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     960-963: TLFN → VCVL
     964-1076: Missing.

Show »
Length:963
Mass (Da):108,211
Checksum:iB5F260D26383BDD2
GO
Isoform 3 (identifier: Q32MH5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-5: MKPDR → MVFSGNKGLHRE

Note: No experimental confirmation available.
Show »
Length:1,083
Mass (Da):122,398
Checksum:iA7519EA191A38F42
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y3Q9H0Y3Q9_HUMAN
Protein FAM214A
FAM214A
938Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WV94A0A087WV94_HUMAN
Protein FAM214A
FAM214A
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BNT9H3BNT9_HUMAN
Protein FAM214A
FAM214A
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BVB3H3BVB3_HUMAN
Protein FAM214A
FAM214A
222Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BSJ2H3BSJ2_HUMAN
Protein FAM214A
FAM214A
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTD0H3BTD0_HUMAN
Protein FAM214A
FAM214A
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BUJ2H3BUJ2_HUMAN
Protein FAM214A
FAM214A
142Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BU00H3BU00_HUMAN
Protein FAM214A
FAM214A
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQ29H3BQ29_HUMAN
Protein FAM214A
FAM214A
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA91936 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAA92608 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAG57156 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti41T → I in AAI09128 (PubMed:15489334).Curated1
Sequence conflicti207V → A in BAF85606 (PubMed:14702039).Curated1
Sequence conflicti610T → A in BAF85606 (PubMed:14702039).Curated1
Sequence conflicti610T → A in BAG57301 (PubMed:14702039).Curated1
Sequence conflicti610T → A in AAI09129 (PubMed:15489334).Curated1
Sequence conflicti641Y → C in BAG57301 (PubMed:14702039).Curated1
Sequence conflicti750E → G in BAF85606 (PubMed:14702039).Curated1
Sequence conflicti956T → A in BAA91936 (PubMed:14702039).Curated1
Sequence conflicti1028Q → R in AAH83498 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038258135Q → R. Corresponds to variant dbSNP:rs8036680Ensembl.1
Natural variantiVAR_038259560V → I4 PublicationsCorresponds to variant dbSNP:rs12915981Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0424351 – 5MKPDR → MVFSGNKGLHRE in isoform 3. 1 Publication5
Alternative sequenceiVSP_030580960 – 963TLFN → VCVL in isoform 2. 2 Publications4
Alternative sequenceiVSP_030581964 – 1076Missing in isoform 2. 2 PublicationsAdd BLAST113

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB037791 mRNA Translation: BAA92608.1 Different initiation.
AK001842 mRNA Translation: BAA91936.1 Different initiation.
AK292917 mRNA Translation: BAF85606.1
AK293730 mRNA Translation: BAG57156.1 Different initiation.
AK293920 mRNA Translation: BAG57301.1
AC009754 Genomic DNA No translation available.
AC025917 Genomic DNA No translation available.
CH471082 Genomic DNA Translation: EAW77460.1
BC040548 mRNA Translation: AAH40548.1
BC058839 mRNA Translation: AAH58839.1
BC083498 mRNA Translation: AAH83498.1
BC109127 mRNA Translation: AAI09128.1
BC109128 mRNA Translation: AAI09129.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45263.1 [Q32MH5-1]
CCDS66773.1 [Q32MH5-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001273424.1, NM_001286495.1 [Q32MH5-3]
NP_062546.2, NM_019600.3 [Q32MH5-1]
XP_005254604.1, XM_005254547.2 [Q32MH5-1]
XP_005254605.1, XM_005254548.2 [Q32MH5-1]
XP_011520091.1, XM_011521789.2 [Q32MH5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000261844; ENSP00000261844; ENSG00000047346 [Q32MH5-1]
ENST00000534964; ENSP00000444447; ENSG00000047346 [Q32MH5-2]
ENST00000546305; ENSP00000443598; ENSG00000047346 [Q32MH5-3]
ENST00000619572; ENSP00000484641; ENSG00000047346 [Q32MH5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56204

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:56204

UCSC genome browser

More...
UCSCi
uc002acg.6 human [Q32MH5-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB037791 mRNA Translation: BAA92608.1 Different initiation.
AK001842 mRNA Translation: BAA91936.1 Different initiation.
AK292917 mRNA Translation: BAF85606.1
AK293730 mRNA Translation: BAG57156.1 Different initiation.
AK293920 mRNA Translation: BAG57301.1
AC009754 Genomic DNA No translation available.
AC025917 Genomic DNA No translation available.
CH471082 Genomic DNA Translation: EAW77460.1
BC040548 mRNA Translation: AAH40548.1
BC058839 mRNA Translation: AAH58839.1
BC083498 mRNA Translation: AAH83498.1
BC109127 mRNA Translation: AAI09128.1
BC109128 mRNA Translation: AAI09129.1
CCDSiCCDS45263.1 [Q32MH5-1]
CCDS66773.1 [Q32MH5-3]
RefSeqiNP_001273424.1, NM_001286495.1 [Q32MH5-3]
NP_062546.2, NM_019600.3 [Q32MH5-1]
XP_005254604.1, XM_005254547.2 [Q32MH5-1]
XP_005254605.1, XM_005254548.2 [Q32MH5-1]
XP_011520091.1, XM_011521789.2 [Q32MH5-1]

3D structure databases

SMRiQ32MH5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi121108, 8 interactors
IntActiQ32MH5, 9 interactors
STRINGi9606.ENSP00000443598

PTM databases

iPTMnetiQ32MH5
PhosphoSitePlusiQ32MH5

Polymorphism and mutation databases

BioMutaiFAM214A
DMDMi166218826

Proteomic databases

EPDiQ32MH5
jPOSTiQ32MH5
PaxDbiQ32MH5
PeptideAtlasiQ32MH5
PRIDEiQ32MH5
ProteomicsDBi61600 [Q32MH5-1]
61601 [Q32MH5-2]
61602 [Q32MH5-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000261844; ENSP00000261844; ENSG00000047346 [Q32MH5-1]
ENST00000534964; ENSP00000444447; ENSG00000047346 [Q32MH5-2]
ENST00000546305; ENSP00000443598; ENSG00000047346 [Q32MH5-3]
ENST00000619572; ENSP00000484641; ENSG00000047346 [Q32MH5-1]
GeneIDi56204
KEGGihsa:56204
UCSCiuc002acg.6 human [Q32MH5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56204

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM214A
HGNCiHGNC:25609 FAM214A
HPAiHPA039369
HPA040180
neXtProtiNX_Q32MH5
OpenTargetsiENSG00000047346
PharmGKBiPA142671609

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2306 Eukaryota
ENOG41115V6 LUCA
GeneTreeiENSGT00940000157573
HOGENOMiHOG000113164
InParanoidiQ32MH5
OMAiVPSKVFR
OrthoDBi383904at2759
PhylomeDBiQ32MH5
TreeFamiTF325496

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM214A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
56204

Protein Ontology

More...
PROi
PR:Q32MH5

Gene expression databases

BgeeiENSG00000047346 Expressed in 202 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiQ32MH5 baseline and differential
GenevisibleiQ32MH5 HS

Family and domain databases

InterProiView protein in InterPro
IPR025261 DUF4210
IPR033473 FAM214/SPAC3H8.04_C
PfamiView protein in Pfam
PF13889 Chromosome_seg, 1 hit
PF13915 DUF4210, 1 hit
SMARTiView protein in SMART
SM01177 DUF4210, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF214A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q32MH5
Secondary accession number(s): A8KA52
, B4DEP5, B4DF40, F5H8G0, Q32MH6, Q4G0R7, Q5XJ16, Q6PDA3, Q9NV24, Q9P2H7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: July 31, 2019
This is version 96 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again