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Protein

Ly6/PLAUR domain-containing protein 4

Gene

LYPD4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-BTA-163125 Post-translational modification: synthesis of GPI-anchored proteins

Names & Taxonomyi

Protein namesi
Recommended name:
Ly6/PLAUR domain-containing protein 4
Gene namesi
Name:LYPD4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 18

Organism-specific databases

VGNCiVGNC:31102 LYPD4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000022675727 – 225Ly6/PLAUR domain-containing protein 4Add BLAST199
PropeptideiPRO_0000226758226 – 246Removed in mature formSequence analysisAdd BLAST21

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi117N-linked (GlcNAc...) asparagineSequence analysis1
Lipidationi225GPI-anchor amidated alanineSequence analysis1

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDbiQ32LD3
PRIDEiQ32LD3

Expressioni

Gene expression databases

BgeeiENSBTAG00000020251

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000026978

Structurei

3D structure databases

ProteinModelPortaliQ32LD3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 223UPAR/Ly6Add BLAST82

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiENOG410J94H Eukaryota
ENOG4111946 LUCA
GeneTreeiENSGT00530000063351
HOGENOMiHOG000013163
HOVERGENiHBG081941
InParanoidiQ32LD3
OMAiRSMVCKL
OrthoDBiEOG091G0IP2
TreeFamiTF337286

Family and domain databases

InterProiView protein in InterPro
IPR016054 LY6_UPA_recep-like
PfamiView protein in Pfam
PF00021 UPAR_LY6, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q32LD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPQHLSPMQ LLCLLGAISS LPWAEALLCY EATSSLFRAV GLHRWQWFLL
60 70 80 90 100
RSMVCKLNEG CEETLVFIEA GTRKGILGFK GCSPASSYPP QVSYLVSPPG
110 120 130 140 150
LSIASYSRVC RTYLCNNLTN MNAILHLKAR TPKTLKSSSH SCPTCVGEHS
160 170 180 190 200
KSCLPNFVSS ESCPRDATKC YSSTVKFQAG FLNTTFLLMG CAREHTSVFA
210 220 230 240
HFHHIGSIRV TEVINIVEKA LFTGAGTPCR SPSWGILLGL LFAFKG
Length:246
Mass (Da):26,872
Last modified:December 6, 2005 - v1
Checksum:iA11EC52A828CFAC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109635 mRNA Translation: AAI09636.1
RefSeqiNP_001069910.1, NM_001076442.1
UniGeneiBt.51208

Genome annotation databases

EnsembliENSBTAT00000026978; ENSBTAP00000026978; ENSBTAG00000020251
GeneIDi617066
KEGGibta:617066

Similar proteinsi

Entry informationi

Entry nameiLYPD4_BOVIN
AccessioniPrimary (citable) accession number: Q32LD3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: December 6, 2005
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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