Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serum amyloid A-4 protein

Gene

SAA4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Major acute phase reactant. Apolipoprotein of the HDL complex (By similarity).By similarity

GO - Molecular functioni

  • chemoattractant activity Source: GO_Central

GO - Biological processi

Keywordsi

Biological processAcute phase

Names & Taxonomyi

Protein namesi
Recommended name:
Serum amyloid A-4 protein
Gene namesi
Name:SAA4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 29

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

HDL, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000028288619 – 129Serum amyloid A-4 proteinAdd BLAST111

Proteomic databases

PaxDbiQ32L76
PRIDEiQ32L76

Expressioni

Gene expression databases

BgeeiENSBTAG00000002963 Expressed in 5 organ(s), highest expression level in testis

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003858

Structurei

3D structure databases

SMRiQ32L76
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SAA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JDSY Eukaryota
ENOG4111APX LUCA
GeneTreeiENSGT00390000004737
HOGENOMiHOG000126881
HOVERGENiHBG016327
InParanoidiQ32L76
KOiK17310
OMAiWYSFFKE
OrthoDBiEOG091G17YH
TreeFamiTF332544

Family and domain databases

InterProiView protein in InterPro
IPR000096 Serum_amyloid_A
PfamiView protein in Pfam
PF00277 SAA, 1 hit
PIRSFiPIRSF002472 Serum_amyloid_A, 1 hit
PRINTSiPR00306 SERUMAMYLOID
SMARTiView protein in SMART
SM00197 SAA, 1 hit
PROSITEiView protein in PROSITE
PS00992 SAA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q32L76-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLIGILFC TLIMGVTGDS WYSFFKEAVQ GASDLWRAYW DMRDANVQNS
60 70 80 90 100
GRYFRARGNY EAAQRGPGGV WAAKIISNVG EYLQGFLYQI YLGDSYGLED
110 120
QVSNRRAEEW GRSGQDPDHF RPAGLPKKY
Length:129
Mass (Da):14,688
Last modified:December 6, 2005 - v1
Checksum:iB8E4DC9BED854A55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109725 mRNA Translation: AAI09726.1
RefSeqiNP_001035595.1, NM_001040505.2
UniGeneiBt.111598

Genome annotation databases

EnsembliENSBTAT00000003858; ENSBTAP00000003858; ENSBTAG00000002963
GeneIDi505308
KEGGibta:505308

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109725 mRNA Translation: AAI09726.1
RefSeqiNP_001035595.1, NM_001040505.2
UniGeneiBt.111598

3D structure databases

SMRiQ32L76
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003858

Proteomic databases

PaxDbiQ32L76
PRIDEiQ32L76

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000003858; ENSBTAP00000003858; ENSBTAG00000002963
GeneIDi505308
KEGGibta:505308

Organism-specific databases

CTDi6291

Phylogenomic databases

eggNOGiENOG410JDSY Eukaryota
ENOG4111APX LUCA
GeneTreeiENSGT00390000004737
HOGENOMiHOG000126881
HOVERGENiHBG016327
InParanoidiQ32L76
KOiK17310
OMAiWYSFFKE
OrthoDBiEOG091G17YH
TreeFamiTF332544

Gene expression databases

BgeeiENSBTAG00000002963 Expressed in 5 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR000096 Serum_amyloid_A
PfamiView protein in Pfam
PF00277 SAA, 1 hit
PIRSFiPIRSF002472 Serum_amyloid_A, 1 hit
PRINTSiPR00306 SERUMAMYLOID
SMARTiView protein in SMART
SM00197 SAA, 1 hit
PROSITEiView protein in PROSITE
PS00992 SAA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSAA4_BOVIN
AccessioniPrimary (citable) accession number: Q32L76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: December 6, 2005
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again