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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotationSAAS annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei22SubstrateUniRule annotation1
Binding sitei26SubstrateUniRule annotation1
Active sitei74UniRule annotation1
Active sitei74Proton donor/acceptorUniRule annotation1
Binding sitei101SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotationImported
Ordered Locus Names:SDY_0938Imported
OrganismiShigella dysenteriae serotype 1 (strain Sd197)Imported
Taxonomic identifieri300267 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002716 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliQ32HU3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 121MGSInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni48 – 51Substrate bindingUniRule annotation4
Regioni68 – 69Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000283729
OMAiRACDVHN
OrthoDBiPOG091H04UH

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

Q32HU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYIMELTTRT LPARKHIALV AHDHCKQMLM SWVERHQPLL EQHVLYATGT
60 70 80 90 100
TGNLISRATG MNVNAMLSGP MGGDQQVGAL ISEGKIDVLI FFWDPLNAVP
110 120 130 140 150
HDPDVKALLR LATVWNIPVA TNVATADFII QSPHFNDAVD ILIPDYQRYL

ADRLK
Length:155
Mass (Da):17,326
Last modified:December 6, 2005 - v1
Checksum:iA9F587D71CA137E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000034 Genomic DNA Translation: ABB61112.1

Genome annotation databases

EnsemblBacteriaiABB61112; ABB61112; SDY_0938

Similar proteinsi

Entry informationi

Entry nameiQ32HU3_SHIDS
AccessioniPrimary (citable) accession number: Q32HU3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: April 25, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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