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UniProtKB - Q30YN8 (Q30YN8_DESAG)

Entry version 99 (02 Dec 2020)
Sequence version 1 (06 Dec 2005)
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Protein

Histidine kinase

Gene

Dde_2411

Organism
Desulfovibrio alaskensis (strain G20) (Desulfovibrio desulfuricans (strain G20))
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.ARBA annotation EC:2.7.13.3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransducerPROSITE-ProRule annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		DALA207559:G1G52-2262-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histidine kinaseARBA annotation (EC:2.7.13.3ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Dde_2411Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDesulfovibrio alaskensis (strain G20) (Desulfovibrio desulfuricans (strain G20))Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri207559 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002710 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 34HelicalSequence analysisAdd BLAST23
Transmembranei319 – 343HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		207559.Dde_2411

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini344 – 396HAMPInterPro annotationAdd BLAST53
Domaini467 – 519PACInterPro annotationAdd BLAST53
Domaini534 – 770Methyl-accepting transducerInterPro annotationAdd BLAST237

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili787 – 807Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0840, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000445_107_19_7

Identification of Orthologs from Complete Genome Data

More...OMAi		KWGDTGY

Database of Orthologous Groups

More...OrthoDBi		429006at2

Family and domain databases

Conserved Domains Database

More...CDDi		cd00130, PAS, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033462, Cache_3-Cache_2
IPR004090, Chemotax_Me-accpt_rcpt
IPR003660, HAMP_dom
IPR004089, MCPsignal_dom
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013767, PAS_fold
IPR029151, Sensor-like_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17201, Cache_3-Cache_2, 1 hit
PF00015, MCPsignal, 1 hit
PF00989, PAS, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00260, CHEMTRNSDUCR

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00304, HAMP, 1 hit
SM00283, MA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103190, SSF103190, 1 hit
SSF55785, SSF55785, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50111, CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885, HAMP, 1 hit
PS50113, PAC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q30YN8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFDKVTLSTK FYSGSIGVLV LAITLLCSVT MWLVSDGMTQ LGTATLQSTT 
        60         70         80         90        100
ENLVTTIEMQ DAITQEKVSS DLSVLEREMQ GYGSLMLSDL HAHQTRMVNQ 
       110        120        130        140        150
VTKEAATATI PALVLTSDEG MTPLYENFEI VDRVQKLIGG TATIFQVLPG 
       160        170        180        190        200
KLLRISTNVL KLDGQRATGT YIPESSPVYK TVMRGETYRG KAFVVNAWYI 
       210        220        230        240        250
TAYKPLRDLG GNIVAVAYVG RKIMTPALTE ALASISVGGL GFAFAYNDKG 
       260        270        280        290        300
EMIYHPEHQG KTLSDIGVEQ YFAGVQNGLV TYMRDGAEQI AYVRHFEPWG 
       310        320        330        340        350
WHIGVQMSRK EALRGMDTMV LTGSLGVAAL ALVAGCISTW LLLRSITGSL 
       360        370        380        390        400
NKLEGFTAAV ATGDYNASVD YKADDAIGKT IAAVRRMVEV IKERLGFSNG 
       410        420        430        440        450
ILQGMATPCI VVDTQEKISY INQPALTLLH AQGSADSWTG QSIGKLFHND 
       460        470        480        490        500
ASRRTILGDT VRDRQSQTNK ELVLQRNGED IFLRVDTAPL HDLDGTLLGA 
       510        520        530        540        550
FGLYTDMTEN HRQNKAMQDK NDIIAQAAEQ ADGVSQNVSA TAAELFGLIE 
       560        570        580        590        600
EANQGAEVQK ERTGEAATAM EEMNATVMEV ARSAAEAASG ADEARARAEE 
       610        620        630        640        650
GARIVRDVIS ASRKVSDEAE NLSSNMQLLG TQVEGISQIM NMINDIADQT 
       660        670        680        690        700
NLLALNAAIE AARAGDAGRG FAVVADEVRK LAEKTMDATK QVTVAITEIQ 
       710        720        730        740        750
EGARRNLEAT RKAVSSIEES TDLANQSGDA LQQILNLSVE TADQVRSIAT 
       760        770        780        790        800
AAEQQSAASE EISHATAEVD RISTETLQAM NRSADAVSQL AEEARRLQQI 

IEMMTSE
Length:807
Mass (Da):87,166
Last modified:December 6, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i38C7AA248253130A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP000112 Genomic DNA Translation: ABB39208.1

NCBI Reference Sequences

More...RefSeqi		WP_011368278.1, NC_007519.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		ABB39208; ABB39208; Dde_2411

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dde:Dde_2411

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000112 Genomic DNA Translation: ABB39208.1
RefSeqiWP_011368278.1, NC_007519.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi207559.Dde_2411

Genome annotation databases

EnsemblBacteriaiABB39208; ABB39208; Dde_2411
KEGGidde:Dde_2411

Phylogenomic databases

eggNOGiCOG0840, Bacteria
HOGENOMiCLU_000445_107_19_7
OMAiKWGDTGY
OrthoDBi429006at2

Enzyme and pathway databases

BioCyciDALA207559:G1G52-2262-MONOMER

Family and domain databases

CDDicd00130, PAS, 1 hit
InterProiView protein in InterPro
IPR033462, Cache_3-Cache_2
IPR004090, Chemotax_Me-accpt_rcpt
IPR003660, HAMP_dom
IPR004089, MCPsignal_dom
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013767, PAS_fold
IPR029151, Sensor-like_sf
PfamiView protein in Pfam
PF17201, Cache_3-Cache_2, 1 hit
PF00015, MCPsignal, 1 hit
PF00989, PAS, 1 hit
PRINTSiPR00260, CHEMTRNSDUCR
SMARTiView protein in SMART
SM00304, HAMP, 1 hit
SM00283, MA, 1 hit
SUPFAMiSSF103190, SSF103190, 1 hit
SSF55785, SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50111, CHEMOTAXIS_TRANSDUC_2, 1 hit
PS50885, HAMP, 1 hit
PS50113, PAC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ30YN8_DESAG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q30YN8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: December 2, 2020
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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