Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-defensin

Gene

Defb23

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Has antibacterial activity.UniRule annotation

GO - Biological processi

Keywordsi

Molecular functionAntibioticUniRule annotation, Antimicrobial, DefensinUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-1461957 Beta defensins
R-MMU-1461973 Defensins

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-defensinUniRule annotation
Gene namesi
Name:Defb23Imported
Synonyms:EG629114Imported
ORF Names:mCG_51783Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3644405 Defb23

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19UniRule annotationAdd BLAST19
ChainiPRO_501502000620 – 166Beta-defensinUniRule annotationAdd BLAST147

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000074681 Expressed in 9 organ(s), highest expression level in female gonad

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096812

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-defensin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J03G Eukaryota
ENOG41119SG LUCA
GeneTreeiENSGT00390000008616
HOGENOMiHOG000112160
HOVERGENiHBG051312
OMAiLMGFGRC
OrthoDBiEOG091G0XGR

Family and domain databases

InterProiView protein in InterPro
IPR020520 Beta-defensin_129
IPR025933 Beta_defensin
PANTHERiPTHR15001 PTHR15001, 1 hit
PTHR15001:SF15 PTHR15001:SF15, 1 hit
PfamiView protein in Pfam
PF13841 Defensin_beta_2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD307569 Beta-defensin_129, 1 hit

Sequencei

Sequence statusi: Complete.

Q30KP0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLLFPLFAS LMLQSQVKSE FATVKRCLVG FGKCKDSCLA DETQMQHCKA
60 70 80 90 100
KKCCIGPKVS ELIKSYLRQE IPHIPDEDIV EMMRTKKNST EEMQGKQALM
110 120 130 140 150
ALFQSRAAKN LLSNTNSAMG PNAFPVKSVT TRTRRRRMGA TASTKMHIKQ
160
SKDSANAAPR PRPGPP
Length:166
Mass (Da):18,486
Last modified:December 6, 2005 - v1
Checksum:iCF94F8A8C83FA145
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844517 Genomic DNA No translation available.
BC132568 mRNA Translation: AAI32569.1
BC132570 mRNA Translation: AAI32571.1
DQ012034 mRNA Translation: AAY59770.1
CH466551 Genomic DNA Translation: EDL05970.1
RefSeqiNP_001033022.1, NM_001037933.2
UniGeneiMm.389372

Genome annotation databases

EnsembliENSMUST00000099206; ENSMUSP00000096812; ENSMUSG00000074681
GeneIDi629114
KEGGimmu:629114
UCSCiuc008nfl.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844517 Genomic DNA No translation available.
BC132568 mRNA Translation: AAI32569.1
BC132570 mRNA Translation: AAI32571.1
DQ012034 mRNA Translation: AAY59770.1
CH466551 Genomic DNA Translation: EDL05970.1
RefSeqiNP_001033022.1, NM_001037933.2
UniGeneiMm.389372

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096812

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000099206; ENSMUSP00000096812; ENSMUSG00000074681
GeneIDi629114
KEGGimmu:629114
UCSCiuc008nfl.2 mouse

Organism-specific databases

CTDi629114
MGIiMGI:3644405 Defb23

Phylogenomic databases

eggNOGiENOG410J03G Eukaryota
ENOG41119SG LUCA
GeneTreeiENSGT00390000008616
HOGENOMiHOG000112160
HOVERGENiHBG051312
OMAiLMGFGRC
OrthoDBiEOG091G0XGR

Enzyme and pathway databases

ReactomeiR-MMU-1461957 Beta defensins
R-MMU-1461973 Defensins

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000074681 Expressed in 9 organ(s), highest expression level in female gonad

Family and domain databases

InterProiView protein in InterPro
IPR020520 Beta-defensin_129
IPR025933 Beta_defensin
PANTHERiPTHR15001 PTHR15001, 1 hit
PTHR15001:SF15 PTHR15001:SF15, 1 hit
PfamiView protein in Pfam
PF13841 Defensin_beta_2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD307569 Beta-defensin_129, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ30KP0_MOUSE
AccessioniPrimary (citable) accession number: Q30KP0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again