UniProtKB - Q2YK82 (Q2YK82_BRUA2)
Protein
Submitted name:
Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain:D-isomer specific 2-hydroxyacid dehydr
Gene
serA-2
Organism
Brucella abortus (strain 2308)
Status
Functioni
GO - Molecular functioni
- NAD binding Source: InterPro
- phosphoglycerate dehydrogenase activity Source: UniProtKB-EC
GO - Biological processi
- L-serine biosynthetic process Source: InterPro
Keywordsi
Molecular function | OxidoreductaseUniRule annotationImported |
Enzyme and pathway databases
BioCyci | BABO359391:G1GJA-2998-MONOMER |
Names & Taxonomyi
Protein namesi | Submitted name: Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain:D-isomer specific 2-hydroxyacid dehydrImported (EC:1.1.1.95Imported) |
Gene namesi | Name:serA-2Imported Ordered Locus Names:BAB2_0783Imported |
Organismi | Brucella abortus (strain 2308)Imported |
Taxonomic identifieri | 359391 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › |
Proteomesi |
|
Structurei
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3K5P | X-ray | 2.15 | A | 1-412 | [»] | |
ProteinModelPortali | Q2YK82 | |||||
SMRi | Q2YK82 | |||||
ModBasei | Search... | |||||
MobiDBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q2YK82 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 341 – 412 | ACTInterPro annotationAdd BLAST | 72 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
HOGENOMi | HOG000136696 |
KOi | K00058 |
OMAi | YHAIGIR |
Family and domain databases
InterProi | View protein in InterPro IPR002912 ACT_dom IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf IPR029015 PGDH_2 |
PANTHERi | PTHR10996:SF165 PTHR10996:SF165, 1 hit |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS51671 ACT, 1 hit PS00065 D_2_HYDROXYACID_DH_1, 1 hit PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q2YK82-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTERLSLSRD RINVLLLEGI SQTAVEYFKS SGYTNVTHLP KALDKADLIK
60 70 80 90 100
AISSAHIIGI RSRTQLTEEI FAAANRLIAV GCFSVGTNQV ELKAARKRGI
110 120 130 140 150
PVFNAPFSNT RSVAELVIGE IIMLMRRIFP RSVSAHAGGW EKTAIGSREV
160 170 180 190 200
RGKTLGIVGY GNIGSQVGNL AESLGMTVRY YDTSDKLQYG NVKPAASLDE
210 220 230 240 250
LLKTSDVVSL HVPSSKSTSK LITEAKLRKM KKGAFLINNA RGSVVDLEAL
260 270 280 290 300
AKVLQEGHLA GAAIDVFPVE PASNGERFST PLQGLENVIL TPHIGGSTEE
310 320 330 340 350
AQERIGTEVT RKLVEYSDVG STVGAVNFPQ VQLPPRPTGT RFMHVHENRP
360 370 380 390 400
GILNSLMNVF SHHHINIASQ FLQTDGEVGY LVMEADGVGE ASDAVLQEIR
410
EIPGTIRARL LY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM040265 Genomic DNA Translation: CAJ12949.1 |
RefSeqi | WP_002967316.1, NZ_KN046823.1 |
Genome annotation databases
EnsemblBacteriai | CAJ12949; CAJ12949; BAB2_0783 |
KEGGi | bmf:BAB2_0783 |
PATRICi | fig|359391.11.peg.475 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM040265 Genomic DNA Translation: CAJ12949.1 |
RefSeqi | WP_002967316.1, NZ_KN046823.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3K5P | X-ray | 2.15 | A | 1-412 | [»] | |
ProteinModelPortali | Q2YK82 | |||||
SMRi | Q2YK82 | |||||
ModBasei | Search... | |||||
MobiDBi | Search... |
Proteomic databases
PRIDEi | Q2YK82 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblBacteriai | CAJ12949; CAJ12949; BAB2_0783 |
KEGGi | bmf:BAB2_0783 |
PATRICi | fig|359391.11.peg.475 |
Phylogenomic databases
HOGENOMi | HOG000136696 |
KOi | K00058 |
OMAi | YHAIGIR |
Enzyme and pathway databases
BioCyci | BABO359391:G1GJA-2998-MONOMER |
Miscellaneous databases
EvolutionaryTracei | Q2YK82 |
Family and domain databases
InterProi | View protein in InterPro IPR002912 ACT_dom IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf IPR029015 PGDH_2 |
PANTHERi | PTHR10996:SF165 PTHR10996:SF165, 1 hit |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS51671 ACT, 1 hit PS00065 D_2_HYDROXYACID_DH_1, 1 hit PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | Q2YK82_BRUA2 | |
Accessioni | Q2YK82Primary (citable) accession number: Q2YK82 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 7, 2006 |
Last sequence update: | February 7, 2006 | |
Last modified: | January 16, 2019 | |
This is version 92 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |