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UniProtKB - Q2YIQ2 (ERYB_BRUA2)
Protein
D-erythritol 1-phosphate dehydrogenase
Gene
eryB
Organism
Brucella abortus (strain 2308)
Status
Functioni
Catalyzes the oxydation of D-erythritol 1-phosphate to D-erythrulose 1-phosphate.
2 PublicationsCatalytic activityi
- EC:1.1.1.4022 Publications
Cofactori
FADBy similarity
: erythritol degradation Pathwayi
This protein is involved in the pathway erythritol degradation, which is part of Carbohydrate metabolism.1 PublicationView all proteins of this organism that are known to be involved in the pathway erythritol degradation and in Carbohydrate metabolism.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 8 – 36 | FADSequence analysisAdd BLAST | 29 |
GO - Molecular functioni
- glycerol-3-phosphate dehydrogenase (quinone) activity Source: InterPro
GO - Biological processi
- glycerol-3-phosphate metabolic process Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | FAD, Flavoprotein, NADP |
Enzyme and pathway databases
UniPathwayi | UPA01066 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:eryB1 Publication Ordered Locus Names:BAB2_0371Imported |
Organismi | Brucella abortus (strain 2308) |
Taxonomic identifieri | 359391 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Hyphomicrobiales › Brucellaceae › Brucella/Ochrobactrum group › Brucella › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000446538 | 1 – 502 | D-erythritol 1-phosphate dehydrogenaseAdd BLAST | 502 |
Expressioni
Inductioni
Induced by erythritol and repressed by EryD.1 Publication
Family & Domainsi
Sequence similaritiesi
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.Curated
Phylogenomic databases
HOGENOMi | CLU_015740_5_0_5 |
OMAi | FAYSDCW |
PhylomeDBi | Q2YIQ2 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q2YIQ2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEPETCDLF VIGGGINGAG VARDAAGRGL KVVLAEKDDL AQGTSSRSGK
60 70 80 90 100
LVHGGLRYLE YYEFRLVREA LIEREVLLNA APHIIWPMRF VLPHSPQDRP
110 120 130 140 150
AWLVRLGLFL YDHLGGRKKL PGTRTLDLKR DPEGTPILDQ YTKGFEYSDC
160 170 180 190 200
WVDDARLVAL NAVGAAEKGA TILTRTPVVS ARRENGGWIV ETRNSDTGET
210 220 230 240 250
RTFRARCIVN CAGPWVTDVI HNVAASTSSR NVRLVKGSHI IVPKFWSGAN
260 270 280 290 300
AYLVQNHDKR VIFINPYEGD KALIGTTDIA YEGRAEDVAA DEKEIDYLIT
310 320 330 340 350
AVNRYFKEKL RREDVLHSFS GVRPLFDDGK GNPSAVTRDY VFDLDETGGA
360 370 380 390 400
PLLNVFGGKI TTFRELAERG MHRLKHIFPQ MGGDWTHDAP LPGGEIANAD
410 420 430 440 450
YETFANTLRD TYPWMPRTLV HHYGRLYGAR TKDVVAGAQN LEGLGRHFGG
460 470 480 490 500
DFHEAEVRYL VAREWAKTAE DILYRRTKHY LHLTEAERAA FVEWFDNANL
VA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 47 | R → A in AAD11520 (PubMed:10708387).Curated | 1 | |
Sequence conflicti | 98 | D → I in AAD11520 (PubMed:10708387).Curated | 1 | |
Sequence conflicti | 166 – 170 | AEKGA → RRKGS in AAD11520 (PubMed:10708387).Curated | 5 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57100 Genomic DNA Translation: AAD11520.1 AM040265 Genomic DNA Translation: CAJ12537.1 |
RefSeqi | WP_002965781.1, NZ_KN046823.1 |
Genome annotation databases
EnsemblBacteriai | CAJ12537; CAJ12537; BAB2_0371 |
GeneIDi | 3827518 |
KEGGi | bmf:BAB2_0371 |
PATRICi | fig|359391.11.peg.2323 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57100 Genomic DNA Translation: AAD11520.1 AM040265 Genomic DNA Translation: CAJ12537.1 |
RefSeqi | WP_002965781.1, NZ_KN046823.1 |
3D structure databases
SMRi | Q2YIQ2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 359391.BAB2_0371 |
Genome annotation databases
EnsemblBacteriai | CAJ12537; CAJ12537; BAB2_0371 |
GeneIDi | 3827518 |
KEGGi | bmf:BAB2_0371 |
PATRICi | fig|359391.11.peg.2323 |
Phylogenomic databases
HOGENOMi | CLU_015740_5_0_5 |
OMAi | FAYSDCW |
PhylomeDBi | Q2YIQ2 |
Enzyme and pathway databases
UniPathwayi | UPA01066 |
Miscellaneous databases
PROi | PR:Q2YIQ2 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ERYB_BRUA2 | |
Accessioni | Q2YIQ2Primary (citable) accession number: Q2YIQ2 Secondary accession number(s): Q9ZB31 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 10, 2019 |
Last sequence update: | February 7, 2006 | |
Last modified: | February 23, 2022 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families