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Protein

Syntaxin-binding protein 6

Gene

STXBP6

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-binding protein 6
Gene namesi
Name:STXBP6
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002835742 – 210Syntaxin-binding protein 6Add BLAST209

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ2YDL1
PRIDEiQ2YDL1

Interactioni

Subunit structurei

Part of a ternary complex containing SNAP25 and STX1A that can be dissociated by NAPA and NSF. Interacts with STX4A (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028368

Structurei

3D structure databases

ProteinModelPortaliQ2YDL1
SMRiQ2YDL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 210v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST60

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410INFF Eukaryota
ENOG410ZU11 LUCA
HOGENOMiHOG000132986
HOVERGENiHBG059039
InParanoidiQ2YDL1
KOiK08519

Family and domain databases

CDDicd14681 PH-STXBP6, 1 hit
cd15892 R-SNARE_STXBP6, 1 hit
InterProiView protein in InterPro
IPR028258 Sec3-PIP2_bind
IPR037821 STXBP6_PH
IPR037822 STXBP6_SNARE
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF15277 Sec3-PIP2_bind, 1 hit
PF00957 Synaptobrevin, 1 hit
SMARTiView protein in SMART
SM01313 Sec3-PIP2_bind, 1 hit
PROSITEiView protein in PROSITE
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2YDL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAKSAISKE IFAPLDERML GAVQVKRRTK KKIPFLATGG QGEYLTYICL
60 70 80 90 100
SVTNKKPTQA SITKVKQFEG STSFVRRSQW MLEQLRQVKG IDPNRDSAEF
110 120 130 140 150
DLLFENAFDQ WVASTASEKC TFFQILHHTC QRYLTDRKPE FINCQSKIMG
160 170 180 190 200
GNSILHSAAD SVTSAVQKAS QALNERGERL GRAEEKTEDL KNSAQQFAET
210
AHKLAMKHKC
Length:210
Mass (Da):23,667
Last modified:December 20, 2005 - v1
Checksum:i7C131A9A7E74B2DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110173 mRNA Translation: AAI10174.1
RefSeqiNP_001069506.1, NM_001076038.2
UniGeneiBt.88441

Genome annotation databases

GeneIDi534718
KEGGibta:534718

Similar proteinsi

Entry informationi

Entry nameiSTXB6_BOVIN
AccessioniPrimary (citable) accession number: Q2YDL1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: December 20, 2005
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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