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Entry version 136 (02 Jun 2021)
Sequence version 1 (10 Jan 2006)
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Protein

Zinc finger protein 284

Gene

ZNF284

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri145 – 169C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri175 – 197C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri203 – 225C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri231 – 253C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri259 – 281C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri287 – 309C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri315 – 337C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri343 – 365C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri371 – 393C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri399 – 421C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 477C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri483 – 505C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri511 – 533C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri539 – 561C2H2-type 15; degeneratePROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q2VY69

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 284
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF284
Synonyms:ZNF284L
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13078, ZNF284

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q2VY69

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000186026.6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000186026

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37654

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q2VY69, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF284

Domain mapping of disease mutations (DMDM)

More...
DMDMi
121941972

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002804031 – 593Zinc finger protein 284Add BLAST593

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q2VY69

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q2VY69

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2VY69

PeptideAtlas

More...
PeptideAtlasi
Q2VY69

PRoteomics IDEntifications database

More...
PRIDEi
Q2VY69

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
61527

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q2VY69

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q2VY69

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in lung, liver, pancreas and thymus. Lower expression in heart, placenta, spleen, prostate, ovary, small intestine and colon. No expression seen in brain, skeletal muscle, kidney, testis and peripheral blood leukocyte.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000186026, Expressed in quadriceps femoris and 183 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2VY69, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000186026, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
131208, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q2VY69, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000411032

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q2VY69, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2VY69

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 78KRABPROSITE-ProRule annotationAdd BLAST71

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri145 – 169C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri175 – 197C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri203 – 225C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri231 – 253C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri259 – 281C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri287 – 309C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri315 – 337C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri343 – 365C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri371 – 393C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri399 – 421C2H2-type 10; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 477C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri483 – 505C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri511 – 533C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri539 – 561C2H2-type 15; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160225

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_31_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2VY69

Identification of Orthologs from Complete Genome Data

More...
OMAi
ISHTCNE

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q2VY69

TreeFam database of animal gene trees

More...
TreeFami
TF341885

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2VY69-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTMFKEAVTF KDVAVVFTEE ELGLLDVSQR KLYRDVMLEN FRNLLSVGHQ
60 70 80 90 100
LSHRDTFHFQ REEKFWIMET ATQREGNSGG KIQTELESVP ETGPHEEWSC
110 120 130 140 150
QQIWEQTASE LTRPQDSISS SQFSTQGDVP SQVDAGLSII HIGETPSEHG
160 170 180 190 200
KCKKFFSDVS ILDLHQQLHS GKISHTCNEY RKRFCYSSAL CLHQKVHMGE
210 220 230 240 250
KRYKCDVCSK AFSQNSQLQT HQRIHTGEKP FKCEQCGKSF SRRSGMYVHC
260 270 280 290 300
KLHTGEKPHI CEECGKAFIH NSQLREHQRI HTGEKPFKCY ICGKSFHSRS
310 320 330 340 350
NLNRHSMVHM QEKSFRCDTC SNSFGQRSAL NSHCMDHTKE KLYKCEECGR
360 370 380 390 400
SFTCRQDLCK HQMDHTGDKP YNCNVCGKGF RWSSCLSRHQ RVHNGETTFK
410 420 430 440 450
CDGCGKRFYM NSQGHSHQRA YREEELYKCQ KCGKGYISKF NLDLHQRVHT
460 470 480 490 500
GERPYNCKEC GKSFRWASGI LRHKRLHTGE KPFKCEECGK RFTENSKLRF
510 520 530 540 550
HQRIHTGEKP YKCEECGKGF RWASTHLTHQ RLHSREKLFQ CEDCGKSSEH
560 570 580 590
SSCLQDQQSD HSGEKTSKCE DCGKRYERRL NLDMILSLFL NDI
Length:593
Mass (Da):69,019
Last modified:January 10, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA147748E360DA84
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031135546K → E. Corresponds to variant dbSNP:rs8113249Ensembl.1
Natural variantiVAR_059909577E → K. Corresponds to variant dbSNP:rs8113249Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY458845 mRNA Translation: AAS13443.1
AY166789 mRNA Translation: AAO45838.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46099.1

NCBI Reference Sequences

More...
RefSeqi
NP_001032902.1, NM_001037813.3
XP_011525209.1, XM_011526907.2
XP_011525210.1, XM_011526908.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000421176; ENSP00000411032; ENSG00000186026

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
342909

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:342909

UCSC genome browser

More...
UCSCi
uc002oyg.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY458845 mRNA Translation: AAS13443.1
AY166789 mRNA Translation: AAO45838.1
CCDSiCCDS46099.1
RefSeqiNP_001032902.1, NM_001037813.3
XP_011525209.1, XM_011526907.2
XP_011525210.1, XM_011526908.2

3D structure databases

SMRiQ2VY69
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi131208, 2 interactors
IntActiQ2VY69, 2 interactors
STRINGi9606.ENSP00000411032

PTM databases

iPTMnetiQ2VY69
PhosphoSitePlusiQ2VY69

Genetic variation databases

BioMutaiZNF284
DMDMi121941972

Proteomic databases

jPOSTiQ2VY69
MassIVEiQ2VY69
PaxDbiQ2VY69
PeptideAtlasiQ2VY69
PRIDEiQ2VY69
ProteomicsDBi61527

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31158, 74 antibodies

The DNASU plasmid repository

More...
DNASUi
342909

Genome annotation databases

EnsembliENST00000421176; ENSP00000411032; ENSG00000186026
GeneIDi342909
KEGGihsa:342909
UCSCiuc002oyg.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
342909

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF284
HGNCiHGNC:13078, ZNF284
HPAiENSG00000186026, Low tissue specificity
neXtProtiNX_Q2VY69
OpenTargetsiENSG00000186026
PharmGKBiPA37654
VEuPathDBiHostDB:ENSG00000186026.6

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000160225
HOGENOMiCLU_002678_31_5_1
InParanoidiQ2VY69
OMAiISHTCNE
OrthoDBi1318335at2759
PhylomeDBiQ2VY69
TreeFamiTF341885

Enzyme and pathway databases

PathwayCommonsiQ2VY69

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
342909, 164 hits in 1011 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF284, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
342909
PharosiQ2VY69, Tdark

Protein Ontology

More...
PROi
PR:Q2VY69
RNActiQ2VY69, protein

Gene expression databases

BgeeiENSG00000186026, Expressed in quadriceps femoris and 183 other tissues
GenevisibleiQ2VY69, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 11 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN284_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2VY69
Secondary accession number(s): Q86WM1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: January 10, 2006
Last modified: June 2, 2021
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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