Zinc finger transcription factor YY1

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• DNA binding Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• metal ion binding Source: UniProtKB-KW
• RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_CentralInferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• sequence-specific DNA binding Source: TAIR <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • Ref.4

    "In vitro identification of DNA-binding motif for the new zinc finger protein AtYY1."
    Wu X., Cheng Y., Li T., Wang Z., Liu J.-Y.
    Acta Biochim. Biophys. Sin. 44:483-489(2012) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION.
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.

GO - Biological processⁱ

• abscisic acid-activated signaling pathway Source: UniProtKB-KW
• defense response Source: UniProtKB-KW
• negative regulation of abscisic acid-activated signaling pathway Source: UniProtKB <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• negative regulation of transcription, DNA-templated Source: TAIRInferred from direct assayⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• positive regulation of transcription, DNA-templated Source: TAIRInferred from direct assayⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• regulation of defense response to fungus Source: UniProtKBInferred from mutant phenotypeⁱ
  • Ref.5

    "MED18 interaction with distinct transcription factors regulates multiple plant functions."
    Lai Z., Schluttenhofer C.M., Bhide K., Shreve J., Thimmapuram J., Lee S.Y., Yun D.-J., Mengiste T.
    Nat. Commun. 5:3064-3064(2014) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INTERACTION WITH MED18, SUBCELLULAR LOCATION.
• regulation of response to salt stress Source: UniProtKBInferred from mutant phenotypeⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• regulation of transcription, DNA-templated Source: UniProtKBInferred from mutant phenotypeⁱ
  • Ref.5

    "MED18 interaction with distinct transcription factors regulates multiple plant functions."
    Lai Z., Schluttenhofer C.M., Bhide K., Shreve J., Thimmapuram J., Lee S.Y., Yun D.-J., Mengiste T.
    Nat. Commun. 5:3064-3064(2014) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INTERACTION WITH MED18, SUBCELLULAR LOCATION.
• response to abscisic acid Source: UniProtKB <p>Inferred from Expression Pattern</p> <p>Covers cases where the annotation is inferred from the timing or location of expression of a gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iep">GO evidence code guide</a></p> Inferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• response to absence of light Source: UniProtKBInferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• response to light stimulus Source: UniProtKBInferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• response to osmotic stress Source: UniProtKBInferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• response to salt stress Source: UniProtKBInferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
• response to water deprivation Source: UniProtKBInferred from expression patternⁱ
  • Ref.6

    "A dual-function transcription factor, AtYY1, is a novel negative regulator of the Arabidopsis ABA response network."
    Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.
    Mol. Plant 9:650-661(2016) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY LIGHT; ABSCISIC ACID; OSMOTIC STRESS; HIGH SALT AND DEHYDRATION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechⁱ

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypeⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityⁱ

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stageⁱ

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Region

Coiled coil

Motif

Compositional bias

Zinc finger

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCHLHKWVT 
        60         70         80         90        100
EDTFSRLKEK EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS 
       110        120        130        140        150
HIHGERQYVC DQEGCGKKFL DSSKLKRHYL IHTGERNYIC TYEGCGKAFS 
       160        170        180        190        200
LDFNLRSHMK THSQENYHIC PYSGCVKRYA HEYKLKNHVA AYHEKNGGGE 
       210        220        230        240        250
TPKYTPPAEK VLRTVKTPAT VCGPSSDRPY ACPYEGCEKA YIHEYKLKLH 
       260        270        280        290        300
LKREHPGHLQ EENADTPTLN KHNGNDRNEI DDGSDQDVYR KHASNGKGQT 
       310        320        330        340        350
HKQQSRAKPN MRTPPAKVGK KGSTSSPAKA RIAKKPWQAK ETFEEVEREE 
       360        370        380 
EEDSEETEED RDNVEDGWRF GENNEDDDDD EETEYED               

        10         20         30         40         50
MLNCIIVLLL LPEDTFSRLK EKEKEPDVPE PEPEPTTEIL FLCSYDGCGK 
        60         70         80         90        100
TFFDVSALRK HSHIHGERQY VCDQEGCGKK FLDSSKLKRH YLIHTGERNY 
       110        120        130        140        150
ICTYEGCGKA FSLDFNLRSH MKTHSQENYH ICPYSGCVKR YAHEYKLKNH 
       160        170        180        190        200
VAAYHEKNGG GETPKYTPPA EKVLRTVKTP ATVCGPSSDR PYACPYEGCE 
       210        220        230        240        250
KAYIHEYKLK LHLKREHPGH LQEENADTPT LNKHNGNDRN EIDDGSDQDV 
       260        270        280        290        300
YRKHASNGKG QTHKQQSRAK PNMRTPPAKV GKKGSTSSPA KARIAKKPWQ 
       310        320        330        340 
AKETFEEVER EEEEDSEETE EDRDNVEDGW RFGENNEDDD DDEETEYED  

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautionⁱ

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityⁱ

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Arabidopsis thaliana
   Arabidopsis thaliana: entries and gene names