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Entry version 86 (07 Oct 2020)
Sequence version 1 (24 Jan 2006)
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Protein

Linoleate 8R-lipoxygenase

Gene

AO090012000863

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDioxygenaseARBA annotation, IsomeraseARBA annotation, Oxidoreductase

Protein family/group databases

PeroxiBase, a peroxidase database

More...
PeroxiBasei
5329, AorLDS02

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Linoleate 8R-lipoxygenaseARBA annotation (EC:1.13.11.60ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AO090012000863Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri510516 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillusAspergillus subgen. Circumdati
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006564 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei50 – 68HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homotetramer.

ARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002329_1_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
MQPMYTK

Family and domain databases

Conserved Domains Database

More...
CDDi
cd09817, linoleate_diol_synthase_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.640.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001128, Cyt_P450
IPR017972, Cyt_P450_CS
IPR036396, Cyt_P450_sf
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal
IPR034812, Ppo_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03098, An_peroxidase, 2 hits
PF00067, p450, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48113, SSF48113, 1 hit
SSF48264, SSF48264, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00086, CYTOCHROME_P450, 1 hit
PS50292, PEROXIDASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2UBU3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGWLSTTTKS SWNPFSTGSS GSSLDSGGSL ASLAFGSKDQ KWFQSVLSKF
60 70 80 90 100
GFNGVLATVL SFFLYALYLK FVSHDEKGLQ TLIKEKASQY LGKIPGLNKL
110 120 130 140 150
SFLKGHLPLG KFSKSLIPKA TKGALGSIAG SSGGILSKLN PFNWKIFNKR
160 170 180 190 200
KIAEEEDDMR YQAGEPYGDP EVLAPTLRDD LKAVGLKAGV QDLKVLLDVV
210 220 230 240 250
KNKGKPIDDR DLTMEKLIAI VSSLPRNSKA REKLTGVLID TLWQSLPHPP
260 270 280 290 300
MTYLGNKYQY RTPDGSYNNP LQPDLGKAGS PYARNVPKLK HMHGVPPDPG
310 320 330 340 350
LLFDLLMARS DETFKENPAG LSSVLFYHAT IIIHDIFRSN RFDPNISDTS
360 370 380 390 400
SYLDLAPLYG SSLEDQMKVR TKVRGLLKPD TFSEKRLIGM PPGVNAILVM
410 420 430 440 450
YNRFHNYVAD NLLKINEGGR FSLPATKSEE DKKAALAKQD EDLFQTARLV
460 470 480 490 500
TNGLYVNISL HDYIRGLANV HHSSSDWTLD PRVKINKIFD SEGVPRGIGN
510 520 530 540 550
QVSVEFNLLY RFHSIISRRD EKWMNEFFAD IFGQDKKVDQ LTPQEFIQGL
560 570 580 590 600
YRFEQSIPED PSEREFGGLK RGENGKFSDA DLVQLMKDSM EDPAGCFGAR
610 620 630 640 650
MVPKALRVIE ILGIIQARKW QLASLNETRD FFKLKRHETF EDVNSNHEIA
660 670 680 690 700
DLLRKLYDDP DMVEMYPGLV GHGGCTPYTV GRAVFSDAVT LVRSDRFLTI
710 720 730 740 750
DYTASNLTCW GYNEVQQDYD ILGGSMFHKL FQRALPNWFP YNSLHITQPM
760 770 780 790 800
YTRKMNEQIA REIGTIDEYT LDDPSPPPKT VIVTKHSTIT KLSKDQANFR
810 820 830 840 850
VIWAKYLNEM IPGRDFSGYM LLGDKPANTD QKTLVKEILY SPAEFVQLLS
860 870 880 890 900
ETAVSVAKEQ LATETLNLTS ELHQVDIVRD VAIPMVTRIL ADLFCLDLKT
910 920 930 940 950
PENPNGTYNV AELYKYIIDV RIFGFNNDDP GLALQRRKWA REGAESLTKT
960 970 980 990 1000
TLRVVSNLPA SEKSGKGIVK GAVSTAKSIA SKIPLVGKLV GDGKGVEGQS
1010 1020 1030 1040 1050
TSGSLRWYGY NVAKELIASG KTPAEVADIS WMNAVGGVGA TIGVFTDVLN
1060 1070 1080 1090 1100
YFLQDENSHH WEEIQKLAAS SDLESSNKSL RQYVLEAQRL TSTQRSIRLC
1110 1120 1130 1140 1150
AGKAVIDGQS FEPGNLVICL LGAACKDPDA VPDPEAFKLD RPSSAYIHFN
1160 1170 1180 1190 1200
VGPHECLGRE IALSCITSLV RVCAGLKNLR AAPGQMGVLK SITTGTEKHF
1210 1220 1230 1240 1250
LNDSWSTLTV DPTTWKIHFE GQGQGIHHPP KIPVTAGRDL NALSNALKKQ
1260 1270 1280 1290 1300
HQDKLQETVS KVANGVTAPL TKLIPSNGPS NGASTPGHLP LPINPFQNGN
1310 1320 1330 1340 1350
GNSNGVANGN THPSLLHQAV SSAAAIPQHA LGTVHDVAHN TVGHLPGGQQ
1360 1370 1380 1390 1400
VTDFTHGLVH PFAGAVSPGQ TQTPPQGQTQ PHQGNWFFLP HGMENAAKQV

PGHLFGQTA
Length:1,409
Mass (Da):155,154
Last modified:January 24, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i36EE30340D476090
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP007161 Genomic DNA Translation: BAE60972.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
BAE60972; BAE60972; AO090012000863

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007161 Genomic DNA Translation: BAE60972.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

PeroxiBasei5329, AorLDS02

Genome annotation databases

EnsemblFungiiBAE60972; BAE60972; AO090012000863

Phylogenomic databases

HOGENOMiCLU_002329_1_0_1
OMAiMQPMYTK

Family and domain databases

CDDicd09817, linoleate_diol_synthase_like, 1 hit
Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR001128, Cyt_P450
IPR017972, Cyt_P450_CS
IPR036396, Cyt_P450_sf
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal
IPR034812, Ppo_N
PfamiView protein in Pfam
PF03098, An_peroxidase, 2 hits
PF00067, p450, 1 hit
SUPFAMiSSF48113, SSF48113, 1 hit
SSF48264, SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086, CYTOCHROME_P450, 1 hit
PS50292, PEROXIDASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ2UBU3_ASPOR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2UBU3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: October 7, 2020
This is version 86 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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