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Protein

Protein asteroid homolog 1

Gene

ASTE1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Possible role in EGF receptor signaling.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein asteroid homolog 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ASTE1
ORF Names:HT001
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000034533.11

Human Gene Nomenclature Database

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HGNCi
HGNC:25021 ASTE1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q2TB18

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000034533

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672577

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ASTE1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
121941802

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003104581 – 679Protein asteroid homolog 1Add BLAST679

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q2TB18

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q2TB18

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q2TB18

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2TB18

PeptideAtlas

More...
PeptideAtlasi
Q2TB18

PRoteomics IDEntifications database

More...
PRIDEi
Q2TB18

ProteomicsDB human proteome resource

More...
ProteomicsDBi
61480

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q2TB18

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q2TB18

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000034533 Expressed in 182 organ(s), highest expression level in amniotic fluid

CleanEx database of gene expression profiles

More...
CleanExi
HS_ASTE1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q2TB18 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2TB18 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037010
HPA037011

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
XRCC4Q134263EBI-2875586,EBI-717592

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118811, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q2TB18, 15 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000264992

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q2TB18

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the asteroid family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFPJ Eukaryota
ENOG4111F5P LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010145

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000034110

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG103560

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2TB18

Database of Orthologous Groups

More...
OrthoDBi
966573at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q2TB18

TreeFam database of animal gene trees

More...
TreeFami
TF324582

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026832 Asteroid
IPR039436 Asteroid_dom
IPR029060 PIN-like_dom_sf
IPR006085 XPG_DNA_repair_N

The PANTHER Classification System

More...
PANTHERi
PTHR15665 PTHR15665, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12813 XPG_I_2, 1 hit
PF00752 XPG_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF88723 SSF88723, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q2TB18-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGIRGLMSFV EDHSNEFFTD LKLRDTKIVI DGYALFHRLC FSSNLDLRYG
60 70 80 90 100
GDYDSFADVV QKFFESLFAC NICPYVVLDG GCDISDKKLT TLKDRAREKI
110 120 130 140 150
QMAHSLSVGG SGYVCPLLIR EVFIQVLIKL RVCFVQCFSE ADRDIMTLAN
160 170 180 190 200
HWNCPVLSSD SDFCIFDLKT GFCPLNSFQW RNMNTIKGTQ NYIPAKCFSL
210 220 230 240 250
DAFCHHFSNM NKALLPLFAV LCGNDHVNLP IMETFLSKAR LPLGATSSKG
260 270 280 290 300
RRHHRILGLL NWLSHFANPT EALDNVLKYL PKKDRENVKE LLCCSMEEYQ
310 320 330 340 350
QSQVKLQDFF QCGTYVCPDA LNLGLPEWVL VALAKGQLSP FISDALVLRR
360 370 380 390 400
TILPTQVENM QQPNAHRISQ PIRQIIYGLL LNASPHLDKT SWNALPPQPL
410 420 430 440 450
AFSEVERINK NIRTSIIDAV ELAKDHSDLS RLTELSLRRR QMLLLETLKV
460 470 480 490 500
KQTILEPIPT SLKLPIAVSC YWLQHTETKA KLHHLQSLLL TMLVGPLIAI
510 520 530 540 550
INSPGKEELQ EDGAKMLYAE FQRVKAQTRL GTRLDLDTAH IFCQWQSCLQ
560 570 580 590 600
MGMYLNQLLS TPLPEPDLTR LYSGSLVHGL CQQLLASTSV ESLLSICPEA
610 620 630 640 650
KQLYEYLFNA TRSYAPAEIF LPKGRSNSKK KRQKKQNTSC SKNRGRTTAH
660 670
TKCWYEGNNR FGLLMVENLE EHSEASNIE
Length:679
Mass (Da):77,093
Last modified:January 24, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i488DE83A8CD8E82B
GO
Isoform 2 (identifier: Q2TB18-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     506-520: KEELQEDGAKMLYAE → NVDPVPRQAQCLAPR
     521-679: Missing.

Note: No experimental confirmation available.
Show »
Length:520
Mass (Da):58,874
Checksum:i7BCB73B4A4019808
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RG30D6RG30_HUMAN
Asteroid homolog 1 (Drosophila), is...
ASTE1 hCG_15790
704Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y982H0Y982_HUMAN
Protein asteroid homolog 1
ASTE1
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6R9W5D6R9W5_HUMAN
Protein asteroid homolog 1
ASTE1
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RGH3D6RGH3_HUMAN
Protein asteroid homolog 1
ASTE1
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RJF1D6RJF1_HUMAN
Protein asteroid homolog 1
ASTE1
49Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y8EM16A0A1Y8EM16_HUMAN
Protein asteroid homolog 1
ASTE1
7Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF14876 differs from that shown. Reason: Frameshift at position 336.Curated
The sequence AAH30274 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI03710 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti303Q → P in AAF14876 (PubMed:10931946).Curated1
Sequence conflicti312 – 314CGT → YGS in AAF14876 (PubMed:10931946).Curated3
Sequence conflicti318P → T in AAF14876 (PubMed:10931946).Curated1
Sequence conflicti321 – 322LN → SD in AAF14876 (PubMed:10931946).Curated2
Sequence conflicti331V → G in AAF14876 (PubMed:10931946).Curated1
Sequence conflicti337 – 339QLS → RVP in AAF14876 (PubMed:10931946).Curated3
Sequence conflicti352 – 354ILP → FLH in AAF14876 (PubMed:10931946).Curated3
Sequence conflicti362Q → R in AAF14876 (PubMed:10931946).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_056699506 – 520KEELQ…MLYAE → NVDPVPRQAQCLAPR in isoform 2. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_056700521 – 679Missing in isoform 2. 1 PublicationAdd BLAST159

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027806 mRNA Translation: BAB55383.1
AK294156 mRNA Translation: BAG57480.1
AC055733 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW79215.1
BC030274 mRNA Translation: AAH30274.2 Different initiation.
BC103709 mRNA Translation: AAI03710.1 Different initiation.
BC110616 mRNA Translation: AAI10617.1
AF113539 mRNA Translation: AAF14876.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3068.1 [Q2TB18-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001275879.1, NM_001288950.1
NP_054784.2, NM_014065.3 [Q2TB18-1]
XP_016861755.1, XM_017006266.1 [Q2TB18-2]
XP_016861756.1, XM_017006267.1 [Q2TB18-2]
XP_016861757.1, XM_017006268.1 [Q2TB18-2]
XP_016861758.1, XM_017006269.1 [Q2TB18-2]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.100878

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000264992; ENSP00000264992; ENSG00000034533 [Q2TB18-1]
ENST00000507978; ENSP00000421019; ENSG00000034533 [Q2TB18-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
28990

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:28990

UCSC genome browser

More...
UCSCi
uc003env.3 human [Q2TB18-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027806 mRNA Translation: BAB55383.1
AK294156 mRNA Translation: BAG57480.1
AC055733 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW79215.1
BC030274 mRNA Translation: AAH30274.2 Different initiation.
BC103709 mRNA Translation: AAI03710.1 Different initiation.
BC110616 mRNA Translation: AAI10617.1
AF113539 mRNA Translation: AAF14876.1 Frameshift.
CCDSiCCDS3068.1 [Q2TB18-1]
RefSeqiNP_001275879.1, NM_001288950.1
NP_054784.2, NM_014065.3 [Q2TB18-1]
XP_016861755.1, XM_017006266.1 [Q2TB18-2]
XP_016861756.1, XM_017006267.1 [Q2TB18-2]
XP_016861757.1, XM_017006268.1 [Q2TB18-2]
XP_016861758.1, XM_017006269.1 [Q2TB18-2]
UniGeneiHs.100878

3D structure databases

ProteinModelPortaliQ2TB18
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118811, 18 interactors
IntActiQ2TB18, 15 interactors
STRINGi9606.ENSP00000264992

PTM databases

iPTMnetiQ2TB18
PhosphoSitePlusiQ2TB18

Polymorphism and mutation databases

BioMutaiASTE1
DMDMi121941802

Proteomic databases

EPDiQ2TB18
jPOSTiQ2TB18
MaxQBiQ2TB18
PaxDbiQ2TB18
PeptideAtlasiQ2TB18
PRIDEiQ2TB18
ProteomicsDBi61480

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264992; ENSP00000264992; ENSG00000034533 [Q2TB18-1]
ENST00000507978; ENSP00000421019; ENSG00000034533 [Q2TB18-2]
GeneIDi28990
KEGGihsa:28990
UCSCiuc003env.3 human [Q2TB18-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
28990
EuPathDBiHostDB:ENSG00000034533.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ASTE1
HGNCiHGNC:25021 ASTE1
HPAiHPA037010
HPA037011
neXtProtiNX_Q2TB18
OpenTargetsiENSG00000034533
PharmGKBiPA142672577

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFPJ Eukaryota
ENOG4111F5P LUCA
GeneTreeiENSGT00390000010145
HOGENOMiHOG000034110
HOVERGENiHBG103560
InParanoidiQ2TB18
OrthoDBi966573at2759
PhylomeDBiQ2TB18
TreeFamiTF324582

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
28990

Protein Ontology

More...
PROi
PR:Q2TB18

Gene expression databases

BgeeiENSG00000034533 Expressed in 182 organ(s), highest expression level in amniotic fluid
CleanExiHS_ASTE1
ExpressionAtlasiQ2TB18 baseline and differential
GenevisibleiQ2TB18 HS

Family and domain databases

InterProiView protein in InterPro
IPR026832 Asteroid
IPR039436 Asteroid_dom
IPR029060 PIN-like_dom_sf
IPR006085 XPG_DNA_repair_N
PANTHERiPTHR15665 PTHR15665, 1 hit
PfamiView protein in Pfam
PF12813 XPG_I_2, 1 hit
PF00752 XPG_N, 1 hit
SUPFAMiSSF88723 SSF88723, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiASTE1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2TB18
Secondary accession number(s): B4DFL9
, Q3MIB6, Q8N6G4, Q96JY1, Q9UHX6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: January 24, 2006
Last modified: January 16, 2019
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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