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UniProtKB - Q2TAC2 (CCD57_HUMAN)

Entry version 109 (08 May 2019)
Sequence version 3 (10 Apr 2019)
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Protein

Coiled-coil domain-containing protein 57

Gene

CCDC57

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 57
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC57
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:27564 CCDC57

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q2TAC2

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		284001

Open Targets

More...OpenTargetsi		ENSG00000176155

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142672173

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CCDC57

Domain mapping of disease mutations (DMDM)

More...DMDMi		317373337

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002888711 – 915Coiled-coil domain-containing protein 57Add BLAST915

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q2TAC2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q2TAC2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q2TAC2

PeptideAtlas

More...PeptideAtlasi		Q2TAC2

PRoteomics IDEntifications database

More...PRIDEi		Q2TAC2

ProteomicsDB human proteome resource

More...ProteomicsDBi		61457
61458 [Q2TAC2-2]

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q2TAC2-1 [Q2TAC2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q2TAC2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q2TAC2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000176155 Expressed in 166 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q2TAC2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q2TAC2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA023315
HPA023326
HPA023342
HPA023344

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		129725, 56 interactors

Protein interaction database and analysis system

More...IntActi		Q2TAC2, 146 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000374292

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q2TAC2

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili92 – 173Sequence analysisAdd BLAST82
Coiled coili214 – 422Sequence analysisAdd BLAST209
Coiled coili456 – 483Sequence analysisAdd BLAST28
Coiled coili521 – 548Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IJ7V Eukaryota
ENOG410XPZ8 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153251

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000111424

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q2TAC2

Identification of Orthologs from Complete Genome Data

More...OMAi		YENLKWR

Database of Orthologous Groups

More...OrthoDBi		490834at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q2TAC2

TreeFam database of animal gene trees

More...TreeFami		TF333001

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q2TAC2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLPLGSEPAL NELLLRKEEE WRALQAHRTQ LQEAALQDTR SQLEEAQGKL 
        60         70         80         90        100
RCLQEDFVYN LQVLEERDLE LERYDAAFAQ AREWEEARRA EVSELKIEAA 
       110        120        130        140        150
KLRQALAREA RKVEELQQQQ QLAFQEHRLE LERVHSDKNG EIDHHREQYE 
       160        170        180        190        200
NLKWTLERKL EELDGELALQ RQELLLEFES KMRKREHEFR LQADNMSNTA 
       210        220        230        240        250
LSRELKVKLL HKELEALKEA GAKAAESLQR AEATNAELER KLQSRAGELQ 
       260        270        280        290        300
DLEAMSRARV KDLEDKLHSV QLTRKKEEET FKRKHEELDR LAREKDAVLV 
       310        320        330        340        350
AVKGAHVEQL QELQTRVLEL QAHCETLEAQ LRRAEWRQAD TAKEKDAAID 
       360        370        380        390        400
QLREDASTVK SAWDAQIAQL SKEMVSRDLQ IQTLQEEEVK LKAQVARSQQ 
       410        420        430        440        450
DIERYKQQLS LAVERERSLE RDQVQLGLDW QRRCDDIERD QIQKSEALIQ 
       460        470        480        490        500
GLSMAKSQVA AKLQETEQAL QEQEVVLKAV TLERDQAVQA LRMHGLPRPG 
       510        520        530        540        550
AQMLLRQHEE EISKDFPSSE IQRLREQNTS LRNAIAQMRK EMEALSHQIP 
       560        570        580        590        600
PPIQTAAEST DANQPDPEAG GDAATPDYVL ALEAEIRTLK HKFKTLEKHL 
       610        620        630        640        650
EDVLDPLKMS SPHAESQPSV RTSTETTGGS AQAGQAGGSV QAGQAGGSVQ 
       660        670        680        690        700
AGPVSSGLAL RKLGDRVQLL NLLVTRLRQK VLREPLEPAA LQRELPREVD 
       710        720        730        740        750
QVHLEVLELR KQVAELGKHL RIAQHGGAEP SGRKQPPASD AVALGREDAK 
       760        770        780        790        800
SAEDEAPSRH LGKHQPRSAQ VGSRLDALQG PKTQHSIHTV TCKSPRQKED 
       810        820        830        840        850
RSPKPPQAPQ HPEEHGRQSH SSSSFASGTL QDMWRLLDLG SSPSGVTSQG 
       860        870        880        890        900
DSTPELPAPP AADRRPVKMQ AGIATPGMKT AAQAKAKTTG ASRSHPAKAK 
       910 
GCQRPPKIRN YNIMD
Length:915
Mass (Da):103,039
Last modified:April 10, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEACE3433538F7FC2
GO
Isoform 2 (identifier: Q2TAC2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     748-751: DAKS → VGAR
     752-915: Missing.

Show »
Length:751
Mass (Da):85,465
Checksum:i5523C434F52B646F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7N7D6K7N7D6_HUMAN
Coiled-coil domain-containing prote...
CCDC57
490Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PDF5E9PDF5_HUMAN
Coiled-coil domain-containing prote...
CCDC57
352Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRQ8J3KRQ8_HUMAN
Coiled-coil domain-containing prote...
CCDC57
35Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BYI8H7BYI8_HUMAN
Coiled-coil domain-containing prote...
CCDC57
212Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSU5J3KSU5_HUMAN
Coiled-coil domain-containing prote...
CCDC57
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QQX7J3QQX7_HUMAN
Coiled-coil domain-containing prote...
CCDC57
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI10998 differs from that shown. Aberrant splicing.Curated
The sequence EAW89746 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti458Q → K in BAB84885 (PubMed:12693554).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032516237E → Q. Corresponds to variant dbSNP:rs34543170Ensembl.1
Natural variantiVAR_032517321Q → R. Corresponds to variant dbSNP:rs7406116Ensembl.1
Natural variantiVAR_032518480V → M1 PublicationCorresponds to variant dbSNP:rs7209474Ensembl.1
Natural variantiVAR_032519774R → G. Corresponds to variant dbSNP:rs4625783Ensembl.1
Natural variantiVAR_032520776D → N. Corresponds to variant dbSNP:rs7406163Ensembl.1
Natural variantiVAR_032521777A → T. Corresponds to variant dbSNP:rs7406162Ensembl.1
Natural variantiVAR_032522810Q → K. Corresponds to variant dbSNP:rs7213172Ensembl.1
Natural variantiVAR_032523833M → T. Corresponds to variant dbSNP:rs11077969Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_025802748 – 751DAKS → VGAR in isoform 2. 2 Publications4
Alternative sequenceiVSP_025803752 – 915Missing in isoform 2. 2 PublicationsAdd BLAST164

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC129510 Genomic DNA No translation available.
AC132872 Genomic DNA No translation available.
AC135056 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89746.1 Sequence problems.
BC040264 mRNA Translation: AAH40264.1
BC110997 mRNA Translation: AAI10998.1 Sequence problems.
AK074059 mRNA Translation: BAB84885.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11803.1 [Q2TAC2-2]

NCBI Reference Sequences

More...RefSeqi		NP_001303250.1, NM_001316321.1 [Q2TAC2-2]
NP_932348.2, NM_198082.2 [Q2TAC2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000392343; ENSP00000376154; ENSG00000176155 [Q2TAC2-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		284001

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:284001

UCSC genome browser

More...UCSCi		uc002kdz.2 human [Q2TAC2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129510 Genomic DNA No translation available.
AC132872 Genomic DNA No translation available.
AC135056 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89746.1 Sequence problems.
BC040264 mRNA Translation: AAH40264.1
BC110997 mRNA Translation: AAI10998.1 Sequence problems.
AK074059 mRNA Translation: BAB84885.1
CCDSiCCDS11803.1 [Q2TAC2-2]
RefSeqiNP_001303250.1, NM_001316321.1 [Q2TAC2-2]
NP_932348.2, NM_198082.2 [Q2TAC2-1]

3D structure databases

SMRiQ2TAC2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129725, 56 interactors
IntActiQ2TAC2, 146 interactors
STRINGi9606.ENSP00000374292

PTM databases

iPTMnetiQ2TAC2
PhosphoSitePlusiQ2TAC2

Polymorphism and mutation databases

BioMutaiCCDC57
DMDMi317373337

Proteomic databases

jPOSTiQ2TAC2
MaxQBiQ2TAC2
PaxDbiQ2TAC2
PeptideAtlasiQ2TAC2
PRIDEiQ2TAC2
ProteomicsDBi61457
61458 [Q2TAC2-2]
TopDownProteomicsiQ2TAC2-1 [Q2TAC2-1]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		284001
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000392343; ENSP00000376154; ENSG00000176155 [Q2TAC2-2]
GeneIDi284001
KEGGihsa:284001
UCSCiuc002kdz.2 human [Q2TAC2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		284001
DisGeNETi284001

GeneCards: human genes, protein and diseases

More...GeneCardsi		CCDC57

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0019621
HGNCiHGNC:27564 CCDC57
HPAiHPA023315
HPA023326
HPA023342
HPA023344
neXtProtiNX_Q2TAC2
OpenTargetsiENSG00000176155
PharmGKBiPA142672173

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IJ7V Eukaryota
ENOG410XPZ8 LUCA
GeneTreeiENSGT00940000153251
HOGENOMiHOG000111424
InParanoidiQ2TAC2
OMAiYENLKWR
OrthoDBi490834at2759
PhylomeDBiQ2TAC2
TreeFamiTF333001

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CCDC57 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		CCDC57

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		284001

Protein Ontology

More...PROi		PR:Q2TAC2

Gene expression databases

BgeeiENSG00000176155 Expressed in 166 organ(s), highest expression level in liver
ExpressionAtlasiQ2TAC2 baseline and differential
GenevisibleiQ2TAC2 HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCD57_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2TAC2
Secondary accession number(s): A6NP51
, A8MQC7, Q8IWG2, Q8TER3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: April 10, 2019
Last modified: May 8, 2019
This is version 109 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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