Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 92 (13 Feb 2019)
Sequence version 3 (22 Feb 2012)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Transmembrane protein 44

Gene

TMEM44

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 44
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM44
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000145014.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25120 TMEM44

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q2T9K0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 29ExtracellularSequence analysisAdd BLAST29
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
Topological domaini51 – 61CytoplasmicSequence analysisAdd BLAST11
Transmembranei62 – 82HelicalSequence analysisAdd BLAST21
Topological domaini83 – 88ExtracellularSequence analysis6
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Topological domaini110 – 135CytoplasmicSequence analysisAdd BLAST26
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Topological domaini157 – 179ExtracellularSequence analysisAdd BLAST23
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Topological domaini201 – 259CytoplasmicSequence analysisAdd BLAST59
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21
Topological domaini281 – 294ExtracellularSequence analysisAdd BLAST14
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21
Topological domaini316 – 475CytoplasmicSequence analysisAdd BLAST160

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000145014

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134916107

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM44

Domain mapping of disease mutations (DMDM)

More...
DMDMi
378405227

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002845441 – 475Transmembrane protein 44Add BLAST475

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei465PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q2T9K0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q2T9K0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2T9K0

PeptideAtlas

More...
PeptideAtlasi
Q2T9K0

PRoteomics IDEntifications database

More...
PRIDEi
Q2T9K0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
61447
61448 [Q2T9K0-2]
61449 [Q2T9K0-4]
61450 [Q2T9K0-6]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q2T9K0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q2T9K0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000145014 Expressed in 155 organ(s), highest expression level in right lung

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q2T9K0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2T9K0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043718

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125003, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q2T9K0, 4 interactors

Molecular INTeraction database

More...
MINTi
Q2T9K0

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q2T9K0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJKG Eukaryota
ENOG4111HX3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018718

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000285985

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG064860

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2T9K0

Identification of Orthologs from Complete Genome Data

More...
OMAi
CWIAAHA

Database of Orthologous Groups

More...
OrthoDBi
657466at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q2T9K0

TreeFam database of animal gene trees

More...
TreeFami
TF337424

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q2T9K0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGEAPSPAPA LWDWDYLDRC FARHRVCISF GLWICASSCW IAAHALLLYL
60 70 80 90 100
RCAQKPRQDQ SALCAACCLL TSLCDTVGAL LARQLTIQVF TGAYLAAIDL
110 120 130 140 150
VNFMFILFPV CGSKFKSNSD REARERKRRR QLRASVFALA LPLSLGPCWA
160 170 180 190 200
LWVAVPKASA TIRGPQRRLL ASLLQENTEI LGYLLGSVAA FGSWASRIPP
210 220 230 240 250
LSRIAPPPTL GITTQHEIWR GQMSKPSQSP SRSPSGHWRA AAQRQVLGTE
260 270 280 290 300
MCRGKTFPSI HLWTRLLSAL AGLLYASAIV AHDQHPEYLL RATPWFLTSL
310 320 330 340 350
GRAALDLAII FLSCVMKSKM RQALGFAKEA RESPDTQALL TCAEKEEENQ
360 370 380 390 400
ENLDWVPLTT LSHCKSLRTM TAISRYMELT IEPVQQAGCS ATRLPGDGQT
410 420 430 440 450
SAGDASLQDP PSYPPVQVIR ARVSSGSSSE VSSINSDLEW DPEDVNLEGS
460 470
KENVELLGSQ VHQDSVRTAH LSDDD
Note: No experimental confirmation available.
Length:475
Mass (Da):52,201
Last modified:February 22, 2012 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18278671EDCFBDB9
GO
Isoform 2 (identifier: Q2T9K0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     205-251: Missing.

Note: No experimental confirmation available.
Show »
Length:428
Mass (Da):47,066
Checksum:i407103BBE7B4732A
GO
Isoform 3 (identifier: Q2T9K0-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     205-251: Missing.
     388-443: GCSATRLPGD...INSDLEWDPE → AVPPGCQVTG...TPTWSGTLKM
     444-475: Missing.

Note: No experimental confirmation available.
Show »
Length:396
Mass (Da):43,800
Checksum:i14387863B691C640
GO
Isoform 4 (identifier: Q2T9K0-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     205-251: Missing.
     439-439: E → EQKYWEALNSEQ

Note: No experimental confirmation available.
Show »
Length:439
Mass (Da):48,444
Checksum:iFA2494D16CCD44AD
GO
Isoform 5 (identifier: Q2T9K0-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     205-251: Missing.
     439-439: E → EKYWEALNSEQ

Note: No experimental confirmation available.
Show »
Length:438
Mass (Da):48,315
Checksum:i4FD04F29BDDF2A87
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C3X7H7C3X7_HUMAN
Transmembrane protein 44
TMEM44
261Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WE47F8WE47_HUMAN
Transmembrane protein 44
TMEM44
150Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCY1F8WCY1_HUMAN
Transmembrane protein 44
TMEM44
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KQW3J3KQW3_HUMAN
Transmembrane protein 44
TMEM44
197Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6PL43Q6PL43_HUMAN
Transmembrane protein 44
TMEM44
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9IZ85C9IZ85_HUMAN
Transmembrane protein 44
TMEM44
113Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH34353 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC86747 differs from that shown. Unlikely isoform. Aberrant splice sites.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03177524H → N1 PublicationCorresponds to variant dbSNP:rs1675955Ensembl.1
Natural variantiVAR_066998232R → H2 PublicationsCorresponds to variant dbSNP:rs12695036Ensembl.1
Natural variantiVAR_066999284Q → R1 PublicationCorresponds to variant dbSNP:rs922282Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_024565205 – 251Missing in isoform 2, isoform 3, isoform 4 and isoform 5. 1 PublicationAdd BLAST47
Alternative sequenceiVSP_024569388 – 443GCSAT…EWDPE → AVPPGCQVTGRRAPEMRPCR TPRRTLPFRSSGPGCLPAAP LRSPPSTPTWSGTLKM in isoform 3. 1 PublicationAdd BLAST56
Alternative sequenceiVSP_039211439E → EQKYWEALNSEQ in isoform 4. Curated1
Alternative sequenceiVSP_046357439E → EKYWEALNSEQ in isoform 5. 1 Publication1
Alternative sequenceiVSP_024571444 – 475Missing in isoform 3. 1 PublicationAdd BLAST32

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK126914 mRNA Translation: BAC86747.1 Sequence problems.
AC046143 Genomic DNA No translation available.
BC034353 mRNA Translation: AAH34353.1 Different initiation.
BC014883 mRNA Translation: AAH14883.1
BC111485 mRNA Translation: AAI11486.1
BC130297 mRNA Translation: AAI30298.1
BC144158 mRNA Translation: AAI44159.1
BC144159 mRNA Translation: AAI44160.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3308.2 [Q2T9K0-7]
CCDS33921.1 [Q2T9K0-2]
CCDS54698.1 [Q2T9K0-4]
CCDS54699.1 [Q2T9K0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001011655.1, NM_001011655.2 [Q2T9K0-2]
NP_001159777.1, NM_001166305.1 [Q2T9K0-1]
NP_001159778.1, NM_001166306.1 [Q2T9K0-4]
NP_612408.3, NM_138399.4 [Q2T9K0-7]
XP_005269428.1, XM_005269371.4 [Q2T9K0-6]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.478729

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000347147; ENSP00000333355; ENSG00000145014 [Q2T9K0-2]
ENST00000381975; ENSP00000371402; ENSG00000145014 [Q2T9K0-4]
ENST00000392432; ENSP00000376227; ENSG00000145014 [Q2T9K0-1]
ENST00000473092; ENSP00000418674; ENSG00000145014 [Q2T9K0-7]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
93109

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:93109

UCSC genome browser

More...
UCSCi
uc003fue.4 human [Q2T9K0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126914 mRNA Translation: BAC86747.1 Sequence problems.
AC046143 Genomic DNA No translation available.
BC034353 mRNA Translation: AAH34353.1 Different initiation.
BC014883 mRNA Translation: AAH14883.1
BC111485 mRNA Translation: AAI11486.1
BC130297 mRNA Translation: AAI30298.1
BC144158 mRNA Translation: AAI44159.1
BC144159 mRNA Translation: AAI44160.1
CCDSiCCDS3308.2 [Q2T9K0-7]
CCDS33921.1 [Q2T9K0-2]
CCDS54698.1 [Q2T9K0-4]
CCDS54699.1 [Q2T9K0-1]
RefSeqiNP_001011655.1, NM_001011655.2 [Q2T9K0-2]
NP_001159777.1, NM_001166305.1 [Q2T9K0-1]
NP_001159778.1, NM_001166306.1 [Q2T9K0-4]
NP_612408.3, NM_138399.4 [Q2T9K0-7]
XP_005269428.1, XM_005269371.4 [Q2T9K0-6]
UniGeneiHs.478729

3D structure databases

ProteinModelPortaliQ2T9K0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125003, 3 interactors
IntActiQ2T9K0, 4 interactors
MINTiQ2T9K0

PTM databases

iPTMnetiQ2T9K0
PhosphoSitePlusiQ2T9K0

Polymorphism and mutation databases

BioMutaiTMEM44
DMDMi378405227

Proteomic databases

jPOSTiQ2T9K0
MaxQBiQ2T9K0
PaxDbiQ2T9K0
PeptideAtlasiQ2T9K0
PRIDEiQ2T9K0
ProteomicsDBi61447
61448 [Q2T9K0-2]
61449 [Q2T9K0-4]
61450 [Q2T9K0-6]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000347147; ENSP00000333355; ENSG00000145014 [Q2T9K0-2]
ENST00000381975; ENSP00000371402; ENSG00000145014 [Q2T9K0-4]
ENST00000392432; ENSP00000376227; ENSG00000145014 [Q2T9K0-1]
ENST00000473092; ENSP00000418674; ENSG00000145014 [Q2T9K0-7]
GeneIDi93109
KEGGihsa:93109
UCSCiuc003fue.4 human [Q2T9K0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
93109
EuPathDBiHostDB:ENSG00000145014.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM44
HGNCiHGNC:25120 TMEM44
HPAiHPA043718
neXtProtiNX_Q2T9K0
OpenTargetsiENSG00000145014
PharmGKBiPA134916107

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJKG Eukaryota
ENOG4111HX3 LUCA
GeneTreeiENSGT00390000018718
HOGENOMiHOG000285985
HOVERGENiHBG064860
InParanoidiQ2T9K0
OMAiCWIAAHA
OrthoDBi657466at2759
PhylomeDBiQ2T9K0
TreeFamiTF337424

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
93109

Protein Ontology

More...
PROi
PR:Q2T9K0

Gene expression databases

BgeeiENSG00000145014 Expressed in 155 organ(s), highest expression level in right lung
ExpressionAtlasiQ2T9K0 baseline and differential
GenevisibleiQ2T9K0 HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMM44_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2T9K0
Secondary accession number(s): A1L3V7
, B7ZLZ5, B7ZLZ6, C9JJ62, E9PGA9, Q0P6F7, Q6ZT47, Q8IXR1, Q8N4G3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: February 22, 2012
Last modified: February 13, 2019
This is version 92 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again