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Entry version 77 (25 May 2022)
Sequence version 1 (24 Jan 2006)
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Protein
Submitted name:

ImcF-related family

Gene

BTH_I2954

Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ImcF-related familyImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:BTH_I2954Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBurkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri271848 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001930 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 30HelicalSequence analysisAdd BLAST19
Transmembranei36 – 57HelicalSequence analysisAdd BLAST22
Transmembranei440 – 461HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini190 – 442IcmF-related_NInterPro annotationAdd BLAST253
Domaini494 – 862IcmF-relatedInterPro annotationAdd BLAST369
Domaini1131 – 1234IcmF_CInterPro annotationAdd BLAST104

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni566 – 616DisorderedSequence analysisAdd BLAST51
Regioni1235 – 1301DisorderedSequence analysisAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili473 – 500Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi599 – 616Polar residuesSequence analysisAdd BLAST18
Compositional biasi1235 – 1256Polar residuesSequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003353_4_0_4

Identification of Orthologs from Complete Genome Data

More...
OMAi
NFVREFM

Database of Orthologous Groups

More...
OrthoDBi
393769at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03348, VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2SUD8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQRFLNVLTH PRTLTIVGFA ALAAVLFIAA DALQIGFVWA AGALAVALAL
60 70 80 90 100
WLATKLWRRS RVRRANRQLG DMLEQQAETG KVSAAVAEPA KRADLDVLRT
110 120 130 140 150
RLADSVKTIK TSKIGQVSGG SALYELPWYI VIGNPAAGKS SAVINSGLQF
160 170 180 190 200
PFADKNSAVI HGIGGTRNCD WFFTTEGILL DTAGRYSVHE EDRSEWLGFL
210 220 230 240 250
DLLKRYRPKA PINGIIVTAS IAELTGNRPE FAINLAKNLR QRVQELTEKL
260 270 280 290 300
EVFAPVYVMF TKADLITGFT EFFSSSDRQE YDRVWGATLP YEPDEKRDVV
310 320 330 340 350
ALFDQRFEEL YDGLKEISVA QLSISRGNKL SPGQLSFPLE FSTIKPALRS
360 370 380 390 400
FLATLFEDNP FQYKPIFRGF YFTSALQEGE TNSAAAQRIA NRFGLDSQSL
410 420 430 440 450
PKPHSAFSKN GFFLRDLFSK VIFADRQTVR QFASPTKTRV RYATFFGFVA
460 470 480 490 500
ALALALGGWT WSTIGNQQLV SNVQADLDNV TRLQQNRNDL QSRLQAMDIL
510 520 530 540 550
EDRIEQLEQF RRDKPLSVSL GLYQGNRLEQ HLLTEYYNGV RQILLAPVSD
560 570 580 590 600
NLASFLKDVN AHPDQLAPMT RAPESGATPA GPMPVSANPA AAPGTAPSPA
610 620 630 640 650
VAPNQQQGGL YNDASPTNVE DAYNALKTYL MLSDKRHVEQ AHLTDQVARF
660 670 680 690 700
WRGWLETNRG NMPRDEMIKS AERMITFYLS RVSDNDWPMI EANLALVDQT
710 720 730 740 750
RENLRRVVRG MPARQRVYEE IKARASTRFA PMTIARIVGE GNTGLVAGSY
760 770 780 790 800
AIPGTFTREA WFQYVQPAIR DAATKELQAK DWVLNTASAD DLTLEGSPEQ
810 820 830 840 850
IQKTLVAMYK TEYAQHWQKF MQGIAVQGFG NFTQAVDAMN KLGDPQDSPI
860 870 880 890 900
RKVLETAYDQ TSWDNPSLAN ATIRKAQTGV VNWVKQWFTR QPGGQIAANV
910 920 930 940 950
DINGNPADVP MGPIGQEFVG LGRIVATHDG TSMLKGYMDT LSKVRTRFNV
960 970 980 990 1000
IKNQGDPGPG ARQLMQQTLD GNGSELADSL KFVDEQMLTG LTDSQRKSLR
1010 1020 1030 1040 1050
PLLVRPLMQA FAVVIQPASV EVNKVWNAQV YQPFQNSLAN KYPFAAGAKV
1060 1070 1080 1090 1100
EAGAGEIAQV FGPDGSIAKF VGATLGPLAV RRGDTLSART WGDMGLALTP
1110 1120 1130 1140 1150
DFTSGFARWV APLAGGAATS AAGSSEPQTV FQVLPQPSSG TTEYTIAIDG
1160 1170 1180 1190 1200
QQLRYRNTPP QWTNFVWPNP QGSPGATLSA TTFDGRTVQL VNEPGRYGLE
1210 1220 1230 1240 1250
KLINSAQRKR RADGTFDLTW TQGSVSVSVT MRIISTSQPT GGGGDQPQQQ
1260 1270 1280 1290 1300
SLRGLRLPSS VADASAGGAA NATAQPGSGG TAAAPQAAVA TASASNAQGA

Q
Length:1,301
Mass (Da):142,135
Last modified:January 24, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDCC1CE3F5BC78B82
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000086 Genomic DNA Translation: ABC39090.1

NCBI Reference Sequences

More...
RefSeqi
WP_011402549.1, NZ_CP008786.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABC39090; ABC39090; BTH_I2954

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bte:BTH_I2954

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000086 Genomic DNA Translation: ABC39090.1
RefSeqiWP_011402549.1, NZ_CP008786.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiABC39090; ABC39090; BTH_I2954
KEGGibte:BTH_I2954

Phylogenomic databases

HOGENOMiCLU_003353_4_0_4
OMAiNFVREFM
OrthoDBi393769at2

Family and domain databases

InterProiView protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like
PfamiView protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR03348, VI_IcmF, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ2SUD8_BURTA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2SUD8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: May 25, 2022
This is version 77 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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