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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Hahella chejuensis (strain KCTC 2396)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciHCHE349521:G1G5E-3593-MONOMER
UniPathwayi
UPA00223;UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:HCH_04006
OrganismiHahella chejuensis (strain KCTC 2396)
Taxonomic identifieri349521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHahellaceaeHahella
Proteomesi
  • UP000000238 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003254981 – 497Probable malate:quinone oxidoreductaseAdd BLAST497

Interactioni

Protein-protein interaction databases

STRINGi349521.HCH_04006

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPQHDMAL
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q2SF51-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVKKADVLL VGGGVMSTTL GTMLMQLDPS LNIVMVERLD HVAHESTYGW
60 70 80 90 100
NNAGTGHAGY CELNYTPETG DGDIEITRAL AINASFEVSL QFWSYLVERG
110 120 130 140 150
GLPSPDEFIN TCPHESFVWG ESDIAFLRKR HQLLSAHHLF KDMEFSDDPR
160 170 180 190 200
TLQDWMPLVM EHRDPMQKVA ATRVRYGSDV DFGSLTRNMV EHLQKNANFE
210 220 230 240 250
LLLSHPVKSL KQTSDGRWNV QLSDSRNGGS KTIDAGFVFL GAGGGALPLL
260 270 280 290 300
QKSGIAEGDG YGGFPVSGQW LVCKKPDIVK RHYAKVYGKA AIGAPPMSVP
310 320 330 340 350
HLDTRIINGE PALLFGPYAG FTTKFLKTGS SFDLFGSIRA NNFGPIMSVG
360 370 380 390 400
INNMDLTRYL IKEAMQSHSD RVKSLLNYFP EAKEDDWTLA EAGQRVQIIK
410 420 430 440 450
RDAQGRGKLE FGTELVASKD GTLAALLGAS PGASVAVKAM VDVIERCFKD
460 470 480 490
RLSSADWTAK LKEMIPSYGE SLVDNAELLH SVRSRTLSVL GLDKKRL
Length:497
Mass (Da):54,587
Last modified:January 24, 2006 - v1
Checksum:iFAD4E8D22F3C6A21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000155 Genomic DNA Translation: ABC30723.1
RefSeqiWP_011397790.1, NC_007645.1

Genome annotation databases

EnsemblBacteriaiABC30723; ABC30723; HCH_04006
KEGGihch:HCH_04006

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000155 Genomic DNA Translation: ABC30723.1
RefSeqiWP_011397790.1, NC_007645.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349521.HCH_04006

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC30723; ABC30723; HCH_04006
KEGGihch:HCH_04006

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPQHDMAL
OrthoDBiPOG091H0B7C

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

BioCyciHCHE349521:G1G5E-3593-MONOMER

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_HAHCH
AccessioniPrimary (citable) accession number: Q2SF51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: January 24, 2006
Last modified: November 7, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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Main funding by: National Institutes of Health

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