Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 125 (02 Jun 2021)
Sequence version 1 (24 Jan 2006)
Previous versions | rss
Add a publicationFeedback
Protein

Disease resistance protein RGA5

Gene

RGA5

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. At the opposite of cultivars Aichi asahi and Sasanishiki, the cultivars Nipponbare, Mokoto and Hitomebore don't recognize the effector avirulence protein AVR-Pia from M.oryzae.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPlant defense
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Disease resistance protein RGA5Curated
Alternative name(s):
Os11gRGA5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RGA5Imported
Ordered Locus Names:Os11g0225300Imported, LOC_Os11g11810Imported
ORF Names:OsJ_33425Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11
  • UP000059680 Componenti: Chromosome 11
  • UP000000763 Componenti: Chromosome 11

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004446621 – 1301Disease resistance protein RGA5Add BLAST1301

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2R8L1

PRoteomics IDEntifications database

More...
PRIDEi
Q2R8L1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in leaves.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q2R8L1, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS11T0225300-01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini181 – 464NB-ARCSequence analysisAdd BLAST284
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati604 – 627LRR 1Sequence analysisAdd BLAST24
Repeati629 – 649LRR 2Sequence analysisAdd BLAST21
Repeati650 – 671LRR 3Sequence analysisAdd BLAST22
Repeati673 – 697LRR 4Sequence analysisAdd BLAST25
Repeati728 – 751LRR 5Sequence analysisAdd BLAST24
Repeati790 – 813LRR 6Sequence analysisAdd BLAST24
Repeati861 – 885LRR 7Sequence analysisAdd BLAST25
Repeati1020 – 1043LRR 8Sequence analysisAdd BLAST24
Repeati1060 – 1083LRR 9Sequence analysisAdd BLAST24
Repeati1117 – 1140LRR 10Sequence analysisAdd BLAST24
Repeati1141 – 1163LRR 11Sequence analysisAdd BLAST23
Repeati1164 – 1186LRR 12Sequence analysisAdd BLAST23

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 177Structured coiled coil (CC) domainBy similarityAdd BLAST177
Regioni1214 – 1249DisorderedSequence analysisAdd BLAST36

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.Curated

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4658, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000837_25_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2R8L1

Identification of Orthologs from Complete Genome Data

More...
OMAi
ETATWDI

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032675, LRR_dom_sf
IPR002182, NB-ARC
IPR027417, P-loop_NTPase
IPR041118, Rx_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00931, NB-ARC, 1 hit
PF18052, Rx_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q2R8L1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAPVSFSLG AMGPLLRKLD SLPVAPEIRL PEPLKDGIEL LKEDLEEIGA
60 70 80 90 100
ALVEQSMVDS PSHRARYWMD EVRDLSYHIE DCIDTMFSMR CGGDDGKPRS
110 120 130 140 150
VRRHKVGRVK VDGFSKTQKP CTRLARIAEL RALVREASER HERYQLGDGR
160 170 180 190 200
ASSSSSSSHR VFTAHGQVPA PCRNLVGMDE PKTKLTNMLT DEAELHMKVV
210 220 230 240 250
CILGSAGIGK TTLAEQVYRK LRWQFDCHAF VRASRKPDMR RLLGAILSQV
260 270 280 290 300
QLRIRISDTS TVQSLIDNLW EYLQKKRYFI VIDELYETAT WDIITSAFPE
310 320 330 340 350
DNNCSRIMTT AGIEGVALEC CSYHSVNIFK MIPLGLDDSA KLFFNRVFGS
360 370 380 390 400
EQQCPYELNE VSYRITAKCG GLPLAVIIIA GLLASLPCKT ELWYNIDGCL
410 420 430 440 450
CSSVTTDIDL DEILKEIISL GYDNLPHYLK TCLLYLSLYS EGFIIWTADL
460 470 480 490 500
LKQWISEGFI AVIDGEDIEE VAESYFYNLV NRGMIQSVKT KYNNQVLCTV
510 520 530 540 550
HHTVFDLIIH KSKEEKFISA IDYSQTMPGN SLEARRLSFH FSNTRYATEV
560 570 580 590 600
AGITLSQVRS FAFLGLLKCM PSIMEFKLLR VLILEFWGDN HGCMSFNVAR
610 620 630 640 650
ICRLFQLRYL KISSQIIIEL PAQIRGLKYL ETLEIDARVT AIPSDIIHLR
660 670 680 690 700
SLLHLYFQDG IVLPDGIGCI RSLRTLKYFD LGSNSEENIR SLGQLTNLRD
710 720 730 740 750
LHLTCSAPKS NQQAKRNLVI LASYTGKLGN LKSVKFSPGD SGMDISFLFY
760 770 780 790 800
GIGISVDRSR TASSLPFSVR TLELPSICIF ARLPDWIGQL RKLHTLNLAV
810 820 830 840 850
RELIENDIDS LAGLPDLIVL SMHIMKAPME RIVFNRKAFP VLKYFKFICG
860 870 880 890 900
TLRMAFQAGA MANLHRLKLG FNAHKGEKYD NILVGIEHLL NLKKIAVRIG
910 920 930 940 950
GAAEAKESDR MAAEAALKEA IRKHLMFLDD LDIARVECVK EEYKCIKKKH
960 970 980 990 1000
KIKIEDSISE KNGDSKKQHS VEKKAVWGKT MKNIADSGVF PEDYTMSREQ
1010 1020 1030 1040 1050
RVAEGFVVGI EKCRAEDAAE RIIRNVPVDY DGLGQVSTSK IQDHLPELAP
1060 1070 1080 1090 1100
RAVQNEKFGS SNDLSIMIQI NKYARLPSYE WRDTDISKLN FRLLRAPMLL
1110 1120 1130 1140 1150
EAVTARCHLL DLILIGSNNI TVLDLGRPTI TKLPASIECL PNLRYLRLQG
1160 1170 1180 1190 1200
TQLKSLSEVI VKMPTIRGLD IKNTKTEELP QGILRMKKLS HLSMGEKQKN
1210 1220 1230 1240 1250
IQVFMEKMQT LAETVQDSDD LSDETEGIAD DEGEFSTRAN ASTPKVDEDE
1260 1270 1280 1290 1300
VDRRANNFIA RFRKQITIRN SGFAKKESSI DERLWIRDLD ECQLSKRGGR

F
Length:1,301
Mass (Da):147,040
Last modified:January 24, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBC26FD09412ADB96
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0P0Y0S6A0A0P0Y0S6_ORYSJ
Os11g0225300 protein
Os11g0225300, OSNPB_110225300
268Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti711N → Y in AK072355 (PubMed:12869764).Curated1
Sequence conflicti843K → E in AK072355 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB604629 mRNA Translation: BAK39932.1
DP000010 Genomic DNA Translation: ABA92208.1
AP008217 Genomic DNA Translation: BAF27900.1
AP014967 Genomic DNA Translation: BAT13285.1
CM000148 Genomic DNA Translation: EEE51878.1
AK072355 mRNA No translation available.

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os11t0225300-01; Os11t0225300-01; Os11g0225300

Gramene; a comparative resource for plants

More...
Gramenei
Os11t0225300-01; Os11t0225300-01; Os11g0225300

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB604629 mRNA Translation: BAK39932.1
DP000010 Genomic DNA Translation: ABA92208.1
AP008217 Genomic DNA Translation: BAF27900.1
AP014967 Genomic DNA Translation: BAT13285.1
CM000148 Genomic DNA Translation: EEE51878.1
AK072355 mRNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4530.OS11T0225300-01

Proteomic databases

PaxDbiQ2R8L1
PRIDEiQ2R8L1

Genome annotation databases

EnsemblPlantsiOs11t0225300-01; Os11t0225300-01; Os11g0225300
GrameneiOs11t0225300-01; Os11t0225300-01; Os11g0225300

Phylogenomic databases

eggNOGiKOG4658, Eukaryota
HOGENOMiCLU_000837_25_1_1
InParanoidiQ2R8L1
OMAiETATWDI

Gene expression databases

ExpressionAtlasiQ2R8L1, baseline and differential

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR032675, LRR_dom_sf
IPR002182, NB-ARC
IPR027417, P-loop_NTPase
IPR041118, Rx_N
PfamiView protein in Pfam
PF00931, NB-ARC, 1 hit
PF18052, Rx_N, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRGA5S_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2R8L1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 18, 2018
Last sequence update: January 24, 2006
Last modified: June 2, 2021
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again