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Entry version 99 (16 Oct 2019)
Sequence version 2 (11 Jul 2006)
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Protein

Ent-sandaracopimara-8(14),15-diene synthase

Gene

KSL10

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in oryzalexin phytoalexins biosynthesis. Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-sandaracopimaradiene.3 Publications

Miscellaneous

ent-sandaracopimaradiene is a precursor of the phytoalexins oryzalexins A-F. Phytoalexins are diterpenoid secondary metabolites involved in the defense mechanism of the plant and produced in response to attack (by a pathogen, elicitor or UV irradiation).

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarityNote: Binds 3 Mg2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi550Magnesium 1By similarity1
Metal bindingi550Magnesium 2By similarity1
Metal bindingi554Magnesium 1By similarity1
Metal bindingi554Magnesium 2By similarity1
Metal bindingi696Magnesium 3By similarity1
Metal bindingi700Magnesium 3By similarity1
Metal bindingi704Magnesium 3By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyase
Biological processPlant defense
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
4.2.3.29 4460
4.2.3.99 4460

Reactome - a knowledgebase of biological pathways and processes for plant species

More...
PlantReactomei
R-OSA-1119371 Oryzalexin A-F biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ent-sandaracopimara-8(14),15-diene synthase (EC:4.2.3.29)
Alternative name(s):
Ent-kaurene synthase-like 10
Short name:
OsKSL10
Ent-sandaracopimaradiene synthase
Gamma-curcumene synthase (EC:4.2.3.94)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KSL10
Synonyms:KS10
Ordered Locus Names:Os12g0491800, LOC_Os12g30824
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003723231 – 815Ent-sandaracopimara-8(14),15-diene synthaseAdd BLAST815

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2QQJ5

PRoteomics IDEntifications database

More...
PRIDEi
Q2QQJ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By UV irradiation.2 Publications

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2QQJ5 OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS12T0491800-01

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2QQJ5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi550 – 554DDXXD motif5

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg2+.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the terpene synthase family.Curated

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000241020

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2QQJ5

KEGG Orthology (KO)

More...
KOi
K14037

Identification of Orthologs from Complete Genome Data

More...
OMAi
IGTWSAK

Database of Orthologous Groups

More...
OrthoDBi
372122at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.600.10, 1 hit
1.50.10.130, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008949 Isoprenoid_synthase_dom_sf
IPR001906 Terpene_synth_N
IPR036965 Terpene_synth_N_sf
IPR005630 Terpene_synthase_metal-bd
IPR008930 Terpenoid_cyclase/PrenylTrfase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01397 Terpene_synth, 1 hit
PF03936 Terpene_synth_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48239 SSF48239, 2 hits
SSF48576 SSF48576, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2QQJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPSSICSMG QIPRTSPHYY GMLPKQMSKG HPPMVTRAVG GVEKGEVGGN
60 70 80 90 100
VRSLQVMHSK ELQAKIRKQL QRVELSPSLY DTAWVAMVPE RSSSQAPCYP
110 120 130 140 150
QCIEWILQNQ HDDGSWGINS SSLSVNKDIL LSTLACVVAL KKWNAGSYHI
160 170 180 190 200
KRGLNFVGRN FSVAMDVQNI APVGFNVTFS GLITLASGMG LQLPVWQTDI
210 220 230 240 250
DEIFHLRKIE LERDSGGTIS ARKAFMAYVA EGFGSLQDWD QVMAYQRKNG
260 270 280 290 300
SLFNSPSTTA AAAIHTFNDR TLNYLDSLTN KFGGPVPAMY PQNIYSQLCT
310 320 330 340 350
VDALERTGIS QKFAREIRDI LDTTYRSWLH NEEEVMLDIP TCAMAFRLLR
360 370 380 390 400
THGYDITSDE MAHFSEQSSF DDSIHGYLND TKTLLELFKT SQIRFSCEDL
410 420 430 440 450
VLENIGTWSA KLLKQQLLSN KLSTSAQSEV EYVLKFPLHS TLDRLEHRRN
460 470 480 490 500
IEQFKVEGSK VLKSGYCGSH SNEEILALAV DYFHSSQSVY QQELKYFESW
510 520 530 540 550
VKQCRLDELK FARVMPLIVH FSSAATIFAP ELADARMVLS QTCMLITVYD
560 570 580 590 600
DFFDCPEISR EEKENYIALI EKWDNHAEIG FCSKNVEIVF YAVYNTYKQI
610 620 630 640 650
GEKAALKQNR SIMDQLVEDL VSSAKAMMVE ADWTATKYIP ATMEEYMSNA
660 670 680 690 700
EVSGAFASFV CPPLYFLGLK LSEEDVKSHE YTQLLKLTNV IGRLQNDSQT
710 720 730 740 750
YRKEILAGKV NSVLLRALTD SGNTSPESIE AAKEIVNRDA ESSMVEMRSL
760 770 780 790 800
VFSEGGPIPR PCKDRFWEMC KIVFYFYSED DAYRTPKETM SSARAVILDP
810
LRLIPPPSCP ETLSS
Length:815
Mass (Da):91,930
Last modified:July 11, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF483899E55ACA15D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti68K → R in ABH10735 (PubMed:16956633).Curated1
Sequence conflicti283G → C in BAD54752 (PubMed:15388982).Curated1
Sequence conflicti546I → M in BAD54752 (PubMed:15388982).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ823355 mRNA Translation: ABH10735.1
DP000011 Genomic DNA Translation: ABA98308.2
AP008218 Genomic DNA Translation: BAF29818.1
AP014968 Genomic DNA Translation: BAT17204.1
AB126937 mRNA Translation: BAD54752.1

NCBI Reference Sequences

More...
RefSeqi
XP_015618915.1, XM_015763429.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os12t0491800-01; Os12t0491800-01; Os12g0491800

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4352248

Gramene; a comparative resource for plants

More...
Gramenei
Os12t0491800-01; Os12t0491800-01; Os12g0491800

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4352248

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ823355 mRNA Translation: ABH10735.1
DP000011 Genomic DNA Translation: ABA98308.2
AP008218 Genomic DNA Translation: BAF29818.1
AP014968 Genomic DNA Translation: BAT17204.1
AB126937 mRNA Translation: BAD54752.1
RefSeqiXP_015618915.1, XM_015763429.1

3D structure databases

SMRiQ2QQJ5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS12T0491800-01

Proteomic databases

PaxDbiQ2QQJ5
PRIDEiQ2QQJ5

Genome annotation databases

EnsemblPlantsiOs12t0491800-01; Os12t0491800-01; Os12g0491800
GeneIDi4352248
GrameneiOs12t0491800-01; Os12t0491800-01; Os12g0491800
KEGGiosa:4352248

Phylogenomic databases

HOGENOMiHOG000241020
InParanoidiQ2QQJ5
KOiK14037
OMAiIGTWSAK
OrthoDBi372122at2759

Enzyme and pathway databases

BRENDAi4.2.3.29 4460
4.2.3.99 4460
PlantReactomeiR-OSA-1119371 Oryzalexin A-F biosynthesis

Gene expression databases

GenevisibleiQ2QQJ5 OS

Family and domain databases

Gene3Di1.10.600.10, 1 hit
1.50.10.130, 1 hit
InterProiView protein in InterPro
IPR008949 Isoprenoid_synthase_dom_sf
IPR001906 Terpene_synth_N
IPR036965 Terpene_synth_N_sf
IPR005630 Terpene_synthase_metal-bd
IPR008930 Terpenoid_cyclase/PrenylTrfase
PfamiView protein in Pfam
PF01397 Terpene_synth, 1 hit
PF03936 Terpene_synth_C, 1 hit
SUPFAMiSSF48239 SSF48239, 2 hits
SSF48576 SSF48576, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKSL10_ORYSJ
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2QQJ5
Secondary accession number(s): A0A0P0YAB2, Q00G36, Q60HB4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: July 11, 2006
Last modified: October 16, 2019
This is version 99 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
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