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UniProtKB - Q2Q1W5 (Q2Q1W5_DANRE)

Entry version 121 (19 Jan 2022)
Sequence version 1 (24 Jan 2006)
Previous versions | rss
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Protein
Submitted name:

Laminin alpha 5

Gene

lama5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesionARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Laminin alpha 5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lama5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-030131-9823, lama5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Basement membraneARBA annotation, Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500421393430 – 3664Sequence analysisAdd BLAST3635

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi441 ↔ 450PROSITE-ProRule annotation
Disulfide bondi482 ↔ 494PROSITE-ProRule annotation
Disulfide bondi505 ↔ 514PROSITE-ProRule annotation
Disulfide bondi529 ↔ 541PROSITE-ProRule annotation
Disulfide bondi531 ↔ 548PROSITE-ProRule annotation
Disulfide bondi550 ↔ 559PROSITE-ProRule annotation
Disulfide bondi575 ↔ 587PROSITE-ProRule annotation
Disulfide bondi595 ↔ 604PROSITE-ProRule annotation
Disulfide bondi620 ↔ 632PROSITE-ProRule annotation
Disulfide bondi640 ↔ 649PROSITE-ProRule annotation
Disulfide bondi665 ↔ 677PROSITE-ProRule annotation
Disulfide bondi667 ↔ 684PROSITE-ProRule annotation
Disulfide bondi686 ↔ 695PROSITE-ProRule annotation
Disulfide bondi785 ↔ 794PROSITE-ProRule annotation
Disulfide bondi1421 ↔ 1433PROSITE-ProRule annotation
Disulfide bondi1423 ↔ 1440PROSITE-ProRule annotation
Disulfide bondi1442 ↔ 1451PROSITE-ProRule annotation
Disulfide bondi1534 ↔ 1543PROSITE-ProRule annotation
Disulfide bondi1559 ↔ 1571PROSITE-ProRule annotation
Disulfide bondi1561 ↔ 1578PROSITE-ProRule annotation
Disulfide bondi1580 ↔ 1589PROSITE-ProRule annotation
Disulfide bondi1862 ↔ 1871PROSITE-ProRule annotation
Disulfide bondi1975 ↔ 1984PROSITE-ProRule annotation
Disulfide bondi1987 ↔ 2001PROSITE-ProRule annotation
Disulfide bondi2023 ↔ 2032PROSITE-ProRule annotation
Disulfide bondi2051 ↔ 2063PROSITE-ProRule annotation
Disulfide bondi2053 ↔ 2070PROSITE-ProRule annotation
Disulfide bondi2072 ↔ 2081PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 291Laminin N-terminalInterPro annotationAdd BLAST254
Domaini421 – 465Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini482 – 528Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini529 – 574Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini575 – 619Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini620 – 664Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini665 – 710Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini762 – 814Laminin EGF-likeInterPro annotationAdd BLAST53
Domaini1421 – 1466Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini1511 – 1558Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1559 – 1609Laminin EGF-likeInterPro annotationAdd BLAST51
Domaini1630 – 1809Laminin IV type AInterPro annotationAdd BLAST180
Domaini1843 – 1893Laminin EGF-likeInterPro annotationAdd BLAST51
Domaini1950 – 2003Laminin EGF-likeInterPro annotationAdd BLAST54
Domaini2004 – 2050Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini2051 – 2098Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2725 – 2917LAM_G_DOMAINInterPro annotationAdd BLAST193
Domaini2932 – 3100LAM_G_DOMAINInterPro annotationAdd BLAST169
Domaini3107 – 3274LAM_G_DOMAINInterPro annotationAdd BLAST168
Domaini3317 – 3481LAM_G_DOMAINInterPro annotationAdd BLAST165
Domaini3488 – 3662LAM_G_DOMAINInterPro annotationAdd BLAST175

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3278 – 3311DisorderedSequence analysisAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2212 – 2246Sequence analysisAdd BLAST35
Coiled coili2314 – 2334Sequence analysisAdd BLAST21
Coiled coili2346 – 2373Sequence analysisAdd BLAST28
Coiled coili2388 – 2415Sequence analysisAdd BLAST28
Coiled coili2464 – 2484Sequence analysisAdd BLAST21
Coiled coili2541 – 2561Sequence analysisAdd BLAST21
Coiled coili2576 – 2603Sequence analysisAdd BLAST28
Coiled coili2691 – 2711Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3289 – 3311Polar residuesSequence analysisAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalSequence analysis

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...OMAi		RDTYQFG

Database of Orthologous Groups

More...OrthoDBi		2342at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q2Q1W5

Family and domain databases

Conserved Domains Database

More...CDDi		cd00055, EGF_Lam, 19 hits
cd00110, LamG, 5 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR002049, LE_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 19 hits
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
PF00055, Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00181, EGF, 13 hits
SM00180, EGF_Lam, 21 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits
SM00136, LamNT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00022, EGF_1, 2 hits
PS01248, EGF_LAM_1, 7 hits
PS50027, EGF_LAM_2, 14 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit
PS51117, LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2Q1W5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARGPSGRAS RTPVLVFLPL LLLTGTLTAQ ELPVNGVNGF SLHPPYFNLA 
        60         70         80         90        100
EGTKITATAT CGVDENEQPI QDLYCKLVGG PVSGDPSQTI QGQYCDICSS 
       110        120        130        140        150
QDTNRAHPIS NAIDGTERWW QSPPLSRSAK HNQVNVTLDL GQLFHVAYVL 
       160        170        180        190        200
IKFANSPRPD LWVLERSIDF GKTYQPWQFF ASSKRDCIER FGQRTIERIY 
       210        220        230        240        250
HDDDVICTTE YSRIVPLENG EIVVSLVNGR PGAMNFSYSP VLREFTKATN 
       260        270        280        290        300
IRLRFLRTNT LLGHLMGKTL RDPTVTRKYY YSIKDISIGG RCVCNGHAEA 
       310        320        330        340        350
CNAQDPNDPY KLQCDCQHNT CGTSCDGCCP GFNQFPWKPA TTYSANECEP 
       360        370        380        390        400
CNCHRHSSEC YYDPEIDQRR SSLDMQGEYN GGGVCVECQH HTTGVNCERC 
       410        420        430        440        450
IPGYYRSPDH PLESPFACSK CQCESEFTEG TCEDRTGRCY CKPNYTGENC 
       460        470        480        490        500
DQCAEGYEHF PECYQVLING EVRPAGENII DCECNAAGTE GNSCRPDPRT 
       510        520        530        540        550
NTCVCKPEFT GEHCDTCSHG YFSINCQRCQ CSGQGCLDGS CDAVTGQCVC 
       560        570        580        590        600
RSGFQGYSCE QCAPGYFNYP LCQYCGCSVV GSIPEMCDPA GRCLCRPEFT 
       610        620        630        640        650
GPRCDQCQSG FHSYPNCQVC TCDPRTSLDS SCSELDQCNC RPNYSGPRCQ 
       660        670        680        690        700
QCAPGYYSYP SCTPCDCSVE GSRSSSCDPV SGQCVCLPNI EGQRCDSCSP 
       710        720        730        740        750
GSYGFPLCQL GTCNPAGSVH NDILPTVGSC VCRPYVEGVA CERCKPLYWN 
       760        770        780        790        800
LSPDTIYGCS TCDCNTAGTL SEVAECTQRT GQCFCKPNVC SGTCNVCKDG 
       810        820        830        840        850
FFNLQKDSYF GCQGCQCDIG GSVGQACDER YGRCRCRPNV EGPKCKQPRP 
       860        870        880        890        900
DHYFPDLHHM KFEVEDGTTM DGRPVRFGYN PLEFESFSWR GYAQMSPIQP 
       910        920        930        940        950
RVLVEVVVGS PDLFHVVLHY VNRGGVDVTG QVSVIEDGRH VLCGNCSEQS 
       960        970        980        990       1000
KQIVFAPSSE PTFVNVPQNS FVEPFVLNPG TWTVIIEAEG ILLDYLVLLP 
      1010       1020       1030       1040       1050
SAYYEAPILQ LQVTEPCSYS HTQDASQNCL QYMYLSLDEF PSISSNDASC 
      1060       1070       1080       1090       1100
RSDNHLPRPC HTEKITPRHP SMAICSGNDI SVGLRGRVPV PGEYVLVVEY 
      1110       1120       1130       1140       1150
ASEDQAPQNL TVSVSSAGES THQEQITLLH CKYSFLCRSV SVDDMKRVAL 
      1160       1170       1180       1190       1200
FTISANAEIQ LIAERSSFFL HKVFLIPRAQ FTMEYLKPRV HCISTHGHFA 
      1210       1220       1230       1240       1250
PDSGSCIPSR FQNPPQSLVL KEGQASSVAE PILASAPDPS LYADRPMTST 
      1260       1270       1280       1290       1300
PPTATDNTEH VLLDTSQNAV VYSTRVHALG RYVFILHYHQ PLHPTYNVQV 
      1310       1320       1330       1340       1350
FINGGRIWQG NVNASFCPHG YGCRSVVMSE NQIILDVTDH EVILTLRVPD 
      1360       1370       1380       1390       1400
RKTLWLDYVL VVPEGSYSSS FLSEELLDKS YDFISNCGQN SFYINPSSAS 
      1410       1420       1430       1440       1450
AFCLSSAVSL SSFFNNGAVP CGCHEVGAES DTCESFGGQC RCRPNVIGRD 
      1460       1470       1480       1490       1500
CSQCATGYYG FPNCRPCNCG SRLCEPVTGE CICPPRTLQP DCVTCEPQTF 
      1510       1520       1530       1540       1550
GCHPLVGCEM CNCSRPGVTS MDISCDTNNG QCRCRNNIVG RQCDRCFPGF 
      1560       1570       1580       1590       1600
YGYPNCRPCN CNEAGTEMNV CDSFTGRCLC KENVEGPRCD QCKLGTFHLD 
      1610       1620       1630       1640       1650
PTNAKGCTKC FCFGATDRCH SSDKRRSEIM DMAGWVLLRS DRQEVPVSTY 
      1660       1670       1680       1690       1700
LDQDLVEADL SDVPDVSQDL HWHAPQAYHG DKVSSYGGYL RYRLHTQTMR 
      1710       1720       1730       1740       1750
GDAFLMVETI RPDVILKGNQ MTLVYMEREY PSPEDPHEGI VHLVEESFRH 
      1760       1770       1780       1790       1800
AQTGNSVSRE ELMMVLVALE SLQIRALHSQ SAQSVSLRAA VLEVAENMPS 
      1810       1820       1830       1840       1850
GRHANNVEIC LCPGNYLGDS CQQCAPGYYR DNKGLFLGKC VPCNCNGHSD 
      1860       1870       1880       1890       1900
QCLDGSGICV NCRHNTAGNH CEKCLGGFHH NNTVDGHSVS CSSCPCPLQV 
      1910       1920       1930       1940       1950
ASNNFAIRCV EKPNNMRCLC MPGYAGSKCE RCAPGYYGNP VVIGSTCQPC 
      1960       1970       1980       1990       2000
NCNGNSDPNM LFSDCHPLTG ECQSCMHNTA GPHCEICAPG FYGDAITAKN 
      2010       2020       2030       2040       2050
CTRCNCSPCG TAHCDSHTGQ CHCKPGVVGA QCDRCEHGTF GFDSCTGCRK 
      2060       2070       2080       2090       2100
CDCDASAALV QACDPVNGAC ACQPGVNGPN CHQCAPGHWN YSSNGCRKCE 
      2110       2120       2130       2140       2150
CKGGRCDPRT GECRCTTGLT GKQCDTCLSQ HSVPVQNGAD MHCQPCDSCV 
      2160       2170       2180       2190       2200
MVLLEDLDRI SHFYESVANQ LTSLNASTFA WTQLNRLNAS IADIANAITN 
      2210       2220       2230       2240       2250
YNSTLDKSRN RASVLEGELE IIDSDIKDLE KKASVTQKKK DALEDNINST 
      2260       2270       2280       2290       2300
HTRAQELFGF IKGIMRDVKD IIQQVNRTAQ NETQVMDEKD LARKIAEVES 
      2310       2320       2330       2340       2350
MLRNMRFRGF DYQKNKAKNE LDQANNLVDR VINEIANRTW NNEAVAENIR 
      2360       2370       2380       2390       2400
NKLKQFNEQL MDLRDAMNEA VNNTAQTVEA NNINQKHLED LQKKVNSLHE 
      2410       2420       2430       2440       2450
KYKEVVSQLQ MAEDDVTQVN DLLSMLQDSK EDYEHLAAQL DGARQPLAEK 
      2460       2470       2480       2490       2500
VQKYAPAANK IPLVEAAEKH AEMLEQLANN LSSLISGSNQ DNFIQRALNA 
      2510       2520       2530       2540       2550
SRAYTNIINS VLEAETTALK ANETASMALE NIRDKDLPAQ AAALKNQSTE 
      2560       2570       2580       2590       2600
LLKSAEELNN SSQSLKPRVD TIKMSLLDAE KKKEKMLQDL KDIQNKLNVS 
      2610       2620       2630       2640       2650
RDDIVNSISA AKSAVEQANN TVANVSGVLA PIQKQLEEWQ KQYGDSNATS 
      2660       2670       2680       2690       2700
EDINKALNDA NTSVAALSDT LPKLIKKLDR LHNTTFQPSN ISDSIQRIRQ 
      2710       2720       2730       2740       2750
LIEQARNAAN KVSVSMQFNG KSGVQVRTPS NVADLAAYSS LQMYIKLPSP 
      2760       2770       2780       2790       2800
TIKKKRQTEA TNPQFVLYLG NRDSSKEYMA VTLNGKKLRW HFNVGGSSVD 
      2810       2820       2830       2840       2850
VLMDEDVKND FFNKLILERT LQYGQMSMTT DQDENNIIKR IMEAKGQKGL 
      2860       2870       2880       2890       2900
LNLPAEETVF YVGGFPSTFS PPGTLNLSSP LDFFKGYVEL LSINEELISL 
      2910       2920       2930       2940       2950
YNFEQTFDMN TTTDAPCSRK RPANTPEWVV DGVYFDGTGY VEVLFETQKG 
      2960       2970       2980       2990       3000
DRTFDQTIRL ISQNGILLSF QREDKYVTIA VLDGFLRVFY NVEGSLMPGP 
      3010       3020       3030       3040       3050
GNPTKISNAD KKTLQVILQL NNMKMLVRLD RETLYTLYSE ELNFTGRYFL 
      3060       3070       3080       3090       3100
GGVPEAEMPN DLKSIYLKHG SIRGCFRIIK SMGSFVQIKT MKSSGISFGC 
      3110       3120       3130       3140       3150
PDDLLFTREA HFTGEGYLGL KMDYVDLANS FYGGIGFRTD QQNGLMFYHQ 
      3160       3170       3180       3190       3200
NKDNVCKVML DNGHVLVSTD RKEVKSQKTY NDDNNHYVAV YRDQNVLSIY 
      3210       3220       3230       3240       3250
IDDVLESSGE TGNVTTRRNA LQEGFTYVGG TPESNGPTNL TGCISNFFIK 
      3260       3270       3280       3290       3300
RANEPQIVED LKTALEGRKY TFTCPDASAP LQMLNSPRPK KNAPGNSRSR 
      3310       3320       3330       3340       3350
MARDSCQGDT SVQEVDAHHF SGSTHSHMRF DSLPQAFSKA PHFSISVRVN 
      3360       3370       3380       3390       3400
SSSGLIFHVA GGKGQRMMAL SVSDGHLTLL VNGGKRKTSI RSKKRYSDGL 
      3410       3420       3430       3440       3450
WHTVFVKVEG DRGSLTVDGI DTQNKRVSAG GKSMFAAPLY IGGLPVDHSA 
      3460       3470       3480       3490       3500
AMAGFVGCVR DLKLNEVSLQ SPSVSVGVTP CYQQPLQPGA HFSSRGGFMT 
      3510       3520       3530       3540       3550
IDESLVLGQD LEIQLEVRLD SGSGLLLHTG AKKTHQLSVY LEQGQVTVLM 
      3560       3570       3580       3590       3600
NSGSGEFSFS LTPKESLCDG GWHTIAIVKK SNVIQLHVDS FSEHGVAPKQ 
      3610       3620       3630       3640       3650
SRSNGGKEAV YLGGLPETIT VPGLSSSVQS FQGCVRKAVL NHRPVMLSKP 
      3660 
LSVSGSVGTQ GCPA
Length:3,664
Mass (Da):403,512
Last modified:January 24, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF69BF40C4C105E95
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DQ232730 mRNA Translation: ABB58781.1

NCBI Reference Sequences

More...RefSeqi		NP_001034260.1, NM_001039171.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		321243

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dre:321243

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ232730 mRNA Translation: ABB58781.1
RefSeqiNP_001034260.1, NM_001039171.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi321243
KEGGidre:321243

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		3911
ZFINiZDB-GENE-030131-9823, lama5

Phylogenomic databases

OMAiRDTYQFG
OrthoDBi2342at2759
PhylomeDBiQ2Q1W5

Family and domain databases

CDDicd00055, EGF_Lam, 19 hits
cd00110, LamG, 5 hits
InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR002049, LE_dom
PfamiView protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 19 hits
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
PF00055, Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 13 hits
SM00180, EGF_Lam, 21 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits
SM00136, LamNT, 1 hit
SUPFAMiSSF49899, SSF49899, 5 hits
PROSITEiView protein in PROSITE
PS00022, EGF_1, 2 hits
PS01248, EGF_LAM_1, 7 hits
PS50027, EGF_LAM_2, 14 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit
PS51117, LAMININ_NTER, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ2Q1W5_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2Q1W5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: January 19, 2022
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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