UniProtKB - Q2PG37 (CD123_MACFA)
Protein
Cell division cycle protein 123 homolog
Gene
CDC123
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Functioni
Required for S phase entry of the cell cycle.By similarity
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
Keywordsi
Biological process | Cell cycle, Cell division |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division cycle protein 123 homolog |
Gene namesi | Name:CDC123 ORF Names:QccE-12339 |
Organismi | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) |
Taxonomic identifieri | 9541 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Proteomesi |
|
Subcellular locationi
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000228663 | 1 – 336 | Cell division cycle protein 123 homologAdd BLAST | 336 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 60 | PhosphoserineBy similarity | 1 |
Post-translational modificationi
Phosphorylated.By similarity
Keywords - PTMi
PhosphoproteinFamily & Domainsi
Sequence similaritiesi
Belongs to the CDC123 family.Curated
Phylogenomic databases
eggNOGi | KOG2983, Eukaryota |
GeneTreei | ENSGT00390000003057 |
OMAi | EDIQWSD |
OrthoDBi | 1539674at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR009772, CDC123 |
PANTHERi | PTHR15323, PTHR15323, 1 hit |
Pfami | View protein in Pfam PF07065, D123, 1 hit |
PIRSFi | PIRSF007807, Cdc123, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q2PG37-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKEHVLHCQ FSAWYPLFRG VTIKSVILPL PQNVKDYLLD DGTLVVSGRD
60 70 80 90 100
DPPTHSQPDS DDEAEEIQWS DDENTATLTA PEFPEFATQV QEAINSLGGS
110 120 130 140 150
VFPKLNWSAP RDAYWIAMNS SLKCKTLSDI FLLFKSSDFI TRDFTQPFIH
160 170 180 190 200
CTDDSPDPCI EYELVLRKWC ELIPGAEFRC FVKENKLIGI SQRDYTQYYD
210 220 230 240 250
HISKQKEEIC RCIQDFFKKH IQYKFLDEDF VFDIYRDSRG KVWLIDFNPF
260 270 280 290 300
GEVTDSLLFT WEELISENNL NGDFSEVDAQ EQDSPAFRCT NSEVTVQPSP
310 320 330
YLSYRLPKDF VDLSTGEDAH KLIDFLKLKR NQQEDD
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2K5U544 | A0A2K5U544_MACFA | Cell division cycle protein 123 hom... | 332 | Annotation score: | |||
A0A2K5U533 | A0A2K5U533_MACFA | Cell division cycle protein 123 hom... | 295 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB220400 mRNA Translation: BAE72933.1 |
RefSeqi | NP_001271660.1, NM_001284731.1 |
Genome annotation databases
Ensembli | ENSMFAT00000026158; ENSMFAP00000007468; ENSMFAG00000036128 |
GeneIDi | 102117547 |
KEGGi | mcf:102117547 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB220400 mRNA Translation: BAE72933.1 |
RefSeqi | NP_001271660.1, NM_001284731.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9541.XP_005564679.1 |
Genome annotation databases
Ensembli | ENSMFAT00000026158; ENSMFAP00000007468; ENSMFAG00000036128 |
GeneIDi | 102117547 |
KEGGi | mcf:102117547 |
Organism-specific databases
CTDi | 8872 |
Phylogenomic databases
eggNOGi | KOG2983, Eukaryota |
GeneTreei | ENSGT00390000003057 |
OMAi | EDIQWSD |
OrthoDBi | 1539674at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR009772, CDC123 |
PANTHERi | PTHR15323, PTHR15323, 1 hit |
Pfami | View protein in Pfam PF07065, D123, 1 hit |
PIRSFi | PIRSF007807, Cdc123, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CD123_MACFA | |
Accessioni | Q2PG37Primary (citable) accession number: Q2PG37 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 21, 2006 |
Last sequence update: | February 7, 2006 | |
Last modified: | August 12, 2020 | |
This is version 44 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families