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Entry version 90 (12 Aug 2020)
Sequence version 1 (07 Feb 2006)
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Protein

SCO-spondin

Gene

SSPO

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the modulation of neuronal aggregation (By similarity). May be involved in developmental events during the formation of the central nervous system (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SCO-spondin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SSPO
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18Sequence analysisAdd BLAST18
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024504519 – 5255SCO-spondinAdd BLAST5237

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi97N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi136N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi156N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi255N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi801N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi931N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi972N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1340N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi1363 ↔ 1376PROSITE-ProRule annotation
Disulfide bondi1370 ↔ 1389PROSITE-ProRule annotation
Disulfide bondi1383 ↔ 1397PROSITE-ProRule annotation
Disulfide bondi1401 ↔ 1413PROSITE-ProRule annotation
Disulfide bondi1408 ↔ 1426PROSITE-ProRule annotation
Disulfide bondi1420 ↔ 1435PROSITE-ProRule annotation
Disulfide bondi1440 ↔ 1452PROSITE-ProRule annotation
Disulfide bondi1447 ↔ 1465PROSITE-ProRule annotation
Disulfide bondi1459 ↔ 1476PROSITE-ProRule annotation
Disulfide bondi1480 ↔ 1492PROSITE-ProRule annotation
Disulfide bondi1487 ↔ 1505PROSITE-ProRule annotation
Disulfide bondi1499 ↔ 1514PROSITE-ProRule annotation
Disulfide bondi1516 ↔ 1528PROSITE-ProRule annotation
Disulfide bondi1523 ↔ 1541PROSITE-ProRule annotation
Disulfide bondi1535 ↔ 1550PROSITE-ProRule annotation
Disulfide bondi1556 ↔ 1568PROSITE-ProRule annotation
Disulfide bondi1563 ↔ 1581PROSITE-ProRule annotation
Disulfide bondi1575 ↔ 1592PROSITE-ProRule annotation
Glycosylationi1610N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1617 ↔ 1629PROSITE-ProRule annotation
Disulfide bondi1624 ↔ 1642PROSITE-ProRule annotation
Disulfide bondi1636 ↔ 1651PROSITE-ProRule annotation
Glycosylationi1652N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1655 ↔ 1668PROSITE-ProRule annotation
Disulfide bondi1662 ↔ 1681PROSITE-ProRule annotation
Disulfide bondi1675 ↔ 1692PROSITE-ProRule annotation
Disulfide bondi1700 ↔ 1711PROSITE-ProRule annotation
Disulfide bondi1706 ↔ 1724PROSITE-ProRule annotation
Glycosylationi1713N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1718 ↔ 1733PROSITE-ProRule annotation
Glycosylationi1743N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1749 ↔ 1759PROSITE-ProRule annotation
Disulfide bondi1754 ↔ 1772PROSITE-ProRule annotation
Disulfide bondi1766 ↔ 1789PROSITE-ProRule annotation
Disulfide bondi1801 ↔ 1837PROSITE-ProRule annotation
Disulfide bondi1805 ↔ 1842PROSITE-ProRule annotation
Disulfide bondi1816 ↔ 1827PROSITE-ProRule annotation
Glycosylationi1856N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1857 ↔ 1897PROSITE-ProRule annotation
Disulfide bondi1861 ↔ 1902PROSITE-ProRule annotation
Disulfide bondi1871 ↔ 1881PROSITE-ProRule annotation
Disulfide bondi2003 ↔ 2042PROSITE-ProRule annotation
Disulfide bondi2014 ↔ 2018PROSITE-ProRule annotation
Disulfide bondi2052 ↔ 2057PROSITE-ProRule annotation
Glycosylationi2125N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2162 ↔ 2310PROSITE-ProRule annotation
Glycosylationi2230N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2328 ↔ 2339PROSITE-ProRule annotation
Disulfide bondi2335 ↔ 2352PROSITE-ProRule annotation
Disulfide bondi2346 ↔ 2361PROSITE-ProRule annotation
Disulfide bondi2482 ↔ 2494PROSITE-ProRule annotation
Disulfide bondi2489 ↔ 2507PROSITE-ProRule annotation
Disulfide bondi2501 ↔ 2516PROSITE-ProRule annotation
Disulfide bondi2539 ↔ 2551PROSITE-ProRule annotation
Disulfide bondi2546 ↔ 2564PROSITE-ProRule annotation
Disulfide bondi2558 ↔ 2573PROSITE-ProRule annotation
Disulfide bondi2576 ↔ 2612PROSITE-ProRule annotation
Disulfide bondi2587 ↔ 2591PROSITE-ProRule annotation
Disulfide bondi2622 ↔ 2627PROSITE-ProRule annotation
Disulfide bondi2642 ↔ 2679PROSITE-ProRule annotation
Disulfide bondi2646 ↔ 2684PROSITE-ProRule annotation
Disulfide bondi2657 ↔ 2669PROSITE-ProRule annotation
Glycosylationi2746N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2791 ↔ 2829PROSITE-ProRule annotation
Disulfide bondi2802 ↔ 2806PROSITE-ProRule annotation
Disulfide bondi2839 ↔ 2843PROSITE-ProRule annotation
Disulfide bondi2861 ↔ 2897PROSITE-ProRule annotation
Disulfide bondi2865 ↔ 2902PROSITE-ProRule annotation
Disulfide bondi2881 ↔ 2887PROSITE-ProRule annotation
Disulfide bondi2917 ↔ 2952PROSITE-ProRule annotation
Disulfide bondi2921 ↔ 2957PROSITE-ProRule annotation
Disulfide bondi2932 ↔ 2942PROSITE-ProRule annotation
Glycosylationi3011N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3042N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3061 ↔ 3099PROSITE-ProRule annotation
Glycosylationi3065N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3072 ↔ 3076PROSITE-ProRule annotation
Disulfide bondi3109 ↔ 3114PROSITE-ProRule annotation
Glycosylationi3136N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3238N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3248N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3270 ↔ 3303PROSITE-ProRule annotation
Disulfide bondi3274 ↔ 3308PROSITE-ProRule annotation
Disulfide bondi3285 ↔ 3293PROSITE-ProRule annotation
Glycosylationi3350N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3366N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3392N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3422 ↔ 3468PROSITE-ProRule annotation
Disulfide bondi3426 ↔ 3474PROSITE-ProRule annotation
Disulfide bondi3437 ↔ 3449PROSITE-ProRule annotation
Disulfide bondi3489 ↔ 3524PROSITE-ProRule annotation
Disulfide bondi3492 ↔ 3531PROSITE-ProRule annotation
Disulfide bondi3502 ↔ 3514PROSITE-ProRule annotation
Glycosylationi3598N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3625N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3656 ↔ 3693PROSITE-ProRule annotation
Disulfide bondi3660 ↔ 3699PROSITE-ProRule annotation
Disulfide bondi3671 ↔ 3683PROSITE-ProRule annotation
Disulfide bondi3714 ↔ 3745PROSITE-ProRule annotation
Disulfide bondi3718 ↔ 3750PROSITE-ProRule annotation
Disulfide bondi3729 ↔ 3735PROSITE-ProRule annotation
Glycosylationi3823N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3869N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi3890 ↔ 3928PROSITE-ProRule annotation
Disulfide bondi3894 ↔ 3933PROSITE-ProRule annotation
Disulfide bondi3906 ↔ 3918PROSITE-ProRule annotation
Disulfide bondi3963 ↔ 3998PROSITE-ProRule annotation
Disulfide bondi3967 ↔ 4003PROSITE-ProRule annotation
Disulfide bondi3982 ↔ 3988PROSITE-ProRule annotation
Glycosylationi4018N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4019 ↔ 4055PROSITE-ProRule annotation
Disulfide bondi4030 ↔ 4034PROSITE-ProRule annotation
Disulfide bondi4068 ↔ 4073PROSITE-ProRule annotation
Disulfide bondi4088 ↔ 4125PROSITE-ProRule annotation
Disulfide bondi4092 ↔ 4130PROSITE-ProRule annotation
Disulfide bondi4103 ↔ 4115PROSITE-ProRule annotation
Glycosylationi4174N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4211N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4231 ↔ 4266PROSITE-ProRule annotation
Disulfide bondi4242 ↔ 4246PROSITE-ProRule annotation
Disulfide bondi4276 ↔ 4281PROSITE-ProRule annotation
Glycosylationi4362N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4387 ↔ 4417PROSITE-ProRule annotation
Disulfide bondi4398 ↔ 4400PROSITE-ProRule annotation
Disulfide bondi4427 ↔ 4432PROSITE-ProRule annotation
Glycosylationi4428N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4498N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4548 ↔ 4601PROSITE-ProRule annotation
Disulfide bondi4551 ↔ 4607PROSITE-ProRule annotation
Disulfide bondi4575 ↔ 4591PROSITE-ProRule annotation
Disulfide bondi4611 ↔ 4646PROSITE-ProRule annotation
Disulfide bondi4622 ↔ 4626PROSITE-ProRule annotation
Disulfide bondi4656 ↔ 4661PROSITE-ProRule annotation
Glycosylationi4730N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4747N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4752N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4774 ↔ 4809PROSITE-ProRule annotation
Disulfide bondi4778 ↔ 4814PROSITE-ProRule annotation
Disulfide bondi4789 ↔ 4798PROSITE-ProRule annotation
Disulfide bondi4818 ↔ 4852PROSITE-ProRule annotation
Disulfide bondi4829 ↔ 4833PROSITE-ProRule annotation
Disulfide bondi4863 ↔ 4868PROSITE-ProRule annotation
Glycosylationi4867N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4939N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4970N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi4980 ↔ 5017PROSITE-ProRule annotation
Disulfide bondi4991 ↔ 4995PROSITE-ProRule annotation
Disulfide bondi5027 ↔ 5032PROSITE-ProRule annotation
Glycosylationi5081N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi5122N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi5161 ↔ 5209PROSITE-ProRule annotation
Glycosylationi5169N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi5175 ↔ 5226PROSITE-ProRule annotation
Disulfide bondi5185 ↔ 5242PROSITE-ProRule annotation
Disulfide bondi5189 ↔ 5244PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2PC93

PRoteomics IDEntifications database

More...
PRIDEi
Q2PC93

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9031.ENSGALP00000007857

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2PC93

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 111EMIAdd BLAST93
Domaini193 – 395VWFD 1PROSITE-ProRule annotationAdd BLAST203
Domaini453 – 508TIL 1Sequence analysisAdd BLAST56
Domaini508 – 601VWFC 1PROSITE-ProRule annotationAdd BLAST94
Domaini547 – 755VWFD 2PROSITE-ProRule annotationAdd BLAST209
Domaini809 – 868TIL 2Sequence analysisAdd BLAST60
Domaini868 – 926VWFC 2PROSITE-ProRule annotationAdd BLAST59
Domaini999 – 1207VWFD 3PROSITE-ProRule annotationAdd BLAST209
Domaini1263 – 1319TIL 3Sequence analysisAdd BLAST57
Domaini1362 – 1398LDL-receptor class A 1PROSITE-ProRule annotationAdd BLAST37
Domaini1400 – 1436LDL-receptor class A 2PROSITE-ProRule annotationAdd BLAST37
Domaini1439 – 1477LDL-receptor class A 3PROSITE-ProRule annotationAdd BLAST39
Domaini1479 – 1515LDL-receptor class A 4PROSITE-ProRule annotationAdd BLAST37
Domaini1515 – 1551LDL-receptor class A 5PROSITE-ProRule annotationAdd BLAST37
Domaini1555 – 1593LDL-receptor class A 6PROSITE-ProRule annotationAdd BLAST39
Domaini1616 – 1652LDL-receptor class A 7PROSITE-ProRule annotationAdd BLAST37
Domaini1654 – 1693LDL-receptor class A 8PROSITE-ProRule annotationAdd BLAST40
Domaini1699 – 1734LDL-receptor class A 9PROSITE-ProRule annotationAdd BLAST36
Domaini1748 – 1790LDL-receptor class A 10PROSITE-ProRule annotationAdd BLAST43
Domaini1789 – 1843TSP type-1 1PROSITE-ProRule annotationAdd BLAST55
Domaini1845 – 1903TSP type-1 2PROSITE-ProRule annotationAdd BLAST59
Domaini1907 – 1961TIL 4Sequence analysisAdd BLAST55
Domaini1919 – 1956EGF-like 1Add BLAST38
Domaini1957 – 1983EGF-like 2Add BLAST27
Domaini1961 – 2019VWFC 3PROSITE-ProRule annotationAdd BLAST59
Domaini2002 – 2058TSP type-1 3PROSITE-ProRule annotationAdd BLAST57
Domaini2058 – 2120VWFC 4PROSITE-ProRule annotationAdd BLAST63
Domaini2162 – 2310F5/8 type CPROSITE-ProRule annotationAdd BLAST149
Domaini2327 – 2362LDL-receptor class A 11PROSITE-ProRule annotationAdd BLAST36
Domaini2481 – 2517LDL-receptor class A 12PROSITE-ProRule annotationAdd BLAST37
Domaini2538 – 2574LDL-receptor class A 13PROSITE-ProRule annotationAdd BLAST37
Domaini2575 – 2628TSP type-1 4PROSITE-ProRule annotationAdd BLAST54
Domaini2630 – 2685TSP type-1 5PROSITE-ProRule annotationAdd BLAST56
Domaini2708 – 2750TIL 5Sequence analysisAdd BLAST43
Domaini2790 – 2844TSP type-1 6PROSITE-ProRule annotationAdd BLAST55
Domaini2849 – 2903TSP type-1 7PROSITE-ProRule annotationAdd BLAST55
Domaini2905 – 2958TSP type-1 8PROSITE-ProRule annotationAdd BLAST54
Domaini2971 – 3020TIL 6Sequence analysisAdd BLAST50
Domaini3020 – 3077VWFC 5PROSITE-ProRule annotationAdd BLAST58
Domaini3060 – 3115TSP type-1 9PROSITE-ProRule annotationAdd BLAST56
Domaini3117 – 3158TSP type-1 10PROSITE-ProRule annotationAdd BLAST42
Domaini3165 – 3217TIL 7Sequence analysisAdd BLAST53
Domaini3217 – 3275VWFC 6PROSITE-ProRule annotationAdd BLAST59
Domaini3258 – 3309TSP type-1 11PROSITE-ProRule annotationAdd BLAST52
Domaini3410 – 3475TSP type-1 12PROSITE-ProRule annotationAdd BLAST66
Domaini3477 – 3532TSP type-1 13PROSITE-ProRule annotationAdd BLAST56
Domaini3534 – 3589TIL 8Sequence analysisAdd BLAST56
Domaini3644 – 3700TSP type-1 14PROSITE-ProRule annotationAdd BLAST57
Domaini3702 – 3751TSP type-1 15PROSITE-ProRule annotationAdd BLAST50
Domaini3878 – 3934TSP type-1 16PROSITE-ProRule annotationAdd BLAST57
Domaini3951 – 4004TSP type-1 17PROSITE-ProRule annotationAdd BLAST54
Domaini4018 – 4074TSP type-1 18PROSITE-ProRule annotationAdd BLAST57
Domaini4076 – 4131TSP type-1 19PROSITE-ProRule annotationAdd BLAST56
Domaini4134 – 4189TIL 9Sequence analysisAdd BLAST56
Domaini4230 – 4282TSP type-1 20PROSITE-ProRule annotationAdd BLAST53
Domaini4322 – 4384TSP type-1 21PROSITE-ProRule annotationAdd BLAST63
Domaini4386 – 4433TSP type-1 22PROSITE-ProRule annotationAdd BLAST48
Domaini4437 – 4492TIL 10Sequence analysisAdd BLAST56
Domaini4537 – 4608TSP type-1 23PROSITE-ProRule annotationAdd BLAST72
Domaini4610 – 4662TSP type-1 24PROSITE-ProRule annotationAdd BLAST53
Domaini4675 – 4722TIL 11Sequence analysisAdd BLAST48
Domaini4762 – 4815TSP type-1 25PROSITE-ProRule annotationAdd BLAST54
Domaini4817 – 4869TSP type-1 26PROSITE-ProRule annotationAdd BLAST53
Domaini4872 – 4926TIL 12Sequence analysisAdd BLAST55
Domaini4979 – 5033TSP type-1 27PROSITE-ProRule annotationAdd BLAST55
Domaini5092 – 5150VWFC 7PROSITE-ProRule annotationAdd BLAST59
Domaini5161 – 5248CTCKPROSITE-ProRule annotationAdd BLAST88

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi737 – 742Poly-Ala6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the thrombospondin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1215, Eukaryota
KOG1216, Eukaryota
KOG3611, Eukaryota
KOG4475, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q2PC93

Database of Orthologous Groups

More...
OrthoDBi
12226at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q2PC93

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00057, FA58C, 1 hit
cd00112, LDLa, 12 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.20.100.10, 23 hits
2.60.120.260, 1 hit
4.10.400.10, 13 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006207, Cys_knot_C
IPR000742, EGF-like_dom
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR036055, LDL_receptor-like_sf
IPR023415, LDLR_class-A_CS
IPR002172, LDrepeatLR_classA_rpt
IPR030119, SCO-spondin
IPR036084, Ser_inhib-like_sf
IPR002919, TIL_dom
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf
IPR014853, Unchr_dom_Cys-rich
IPR001007, VWF_dom
IPR001846, VWF_type-D

The PANTHER Classification System

More...
PANTHERi
PTHR11339:SF358, PTHR11339:SF358, 8 hits

Pfam protein domain database

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Pfami
View protein in Pfam
PF00754, F5_F8_type_C, 1 hit
PF00057, Ldl_recept_a, 12 hits
PF01826, TIL, 12 hits
PF00090, TSP_1, 25 hits
PF00093, VWC, 1 hit
PF00094, VWD, 3 hits

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00261, LDLRECEPTOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832, C8, 3 hits
SM00181, EGF, 9 hits
SM00231, FA58C, 1 hit
SM00192, LDLa, 13 hits
SM00209, TSP1, 27 hits
SM00214, VWC, 9 hits
SM00215, VWC_out, 11 hits
SM00216, VWD, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785, SSF49785, 1 hit
SSF57424, SSF57424, 12 hits
SSF57567, SSF57567, 15 hits
SSF82895, SSF82895, 25 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01225, CTCK_2, 1 hit
PS01285, FA58C_1, 1 hit
PS01286, FA58C_2, 1 hit
PS50022, FA58C_3, 1 hit
PS01209, LDLRA_1, 11 hits
PS50068, LDLRA_2, 13 hits
PS50092, TSP1, 27 hits
PS01208, VWFC_1, 1 hit
PS50184, VWFC_2, 2 hits
PS51233, VWFD, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q2PC93-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGIVATVLLW VVTEAARGRW CERTEQVTEE EVVMPRREDV VPCPSMYQYS
60 70 80 90 100
LAGWRIDLNR MRQVYGGERG VPPTSTHPGA AMCYIYRPPE TQLVVRNRTV
110 120 130 140 150
RACCAGWSGP HCTEVEGSLG QCHASWQCQD ALGAHNLSTV SMAECCRQPW
160 170 180 190 200
GHSWRNGSSA LCFACSRQPL TGDVPLPTAP RGPAARHRGP TASCTVWAGS
210 220 230 240 250
RYRSFDGRHF GFQGECAYSL AASTDSTWAV SITPGSPPVL HMTFGLDTVV
260 270 280 290 300
AQGHNISVNG VAVPEGRQHL HGGISVTWLG DFVAVESGLG VHLKLDGRGT
310 320 330 340 350
VYVTVSAELR GSTKGLCGPY NDDPIDDFLR VEGDVAPLAA SFGNSWRIPD
360 370 380 390 400
ANPELSCSDA VEPSPGCAMG STAQRAAEAM CGMLLTDPFR QCHEAVDPHG
410 420 430 440 450
FYEACLELHC REGGTGPSPP PAVCDTLATY VRDCAQRRAY IEWRRPGLCE
460 470 480 490 500
QQCGHGQRYS DCVSSCPASC MAAGTAEEGH CRDDCASGCE CTPGLLLDRG
510 520 530 540 550
ACIPQSACPC LHRGHIYAPG QSIRQRCNQC TCRGGRWLCT QDRCAAECAV
560 570 580 590 600
LGDLHYITFD RRRFSFPGAC EYTLVQDFVE GTLRITAEQE ACGGHQPLSC
610 620 630 640 650
LRALSITVPG ASARLHSTGE VVVDGRVVPL PFASAALTVR RASSSFLLLQ
660 670 680 690 700
TFGAHLLWGL ETPAAYITLQ PAFANKVRGL CGTYNWDQRD DFATPAGDVE
710 720 730 740 750
VGVTAFANKY RVSTDCPVLS PVPFEPCSTY APRRELAAAA CAILHGASFQ
760 770 780 790 800
PCHHLVDREP FHQLCLYDVC ACPAGKHCLC PALAAYAREC AQEGAALSWR
810 820 830 840 850
NESFCGTQCR GGQVYQECSS PCGRTCADLR LDGASSCPSL DNICVSGCNC
860 870 880 890 900
PEGPVLDDGG QCVPPGVCPC QHSSQLYPAG SKIRQGCNAC MCTAGTWSCT
910 920 930 940 950
DAPCPDAAFC PGDLVYVFGS CLRTCDSAEP NGTCTGIADG CVCPPGTVFL
960 970 980 990 1000
DERCVPPEEC PCQHNGRLYH PNDTIVRDCN TCVCRQQRWQ CSSEDCMGTC
1010 1020 1030 1040 1050
VATGDPHYIT FDGRAFSFLG DCEYVLVREA NGLFTVTAEN VPCGTSGVTC
1060 1070 1080 1090 1100
TKSVVVEMGN TVVHMLRGRD VTVNGVSVRP PKVYSGNGLT LQRAGIFLLL
1110 1120 1130 1140 1150
LSRLGLAVLW DGGTRVYIRL QPQHRGRVVG LCGNFDRDAE NDLASQQGVL
1160 1170 1180 1190 1200
EPTAELFGNS WRVSLLCPEV DGTTAQHPCT DNPHRATWAR KRCSILTQRL
1210 1220 1230 1240 1250
FAPCHDEVPC QHFYDWCIFD ACGCDSGGDC ECLCTAIATY AEECSQRGIH
1260 1270 1280 1290 1300
IRWRSQDLCP MQCDGGQEYS ACGPPCPQTC RNLGLELPEH CDTMSCLEGC
1310 1320 1330 1340 1350
FCPEGKVLHE GSCIDPAECP CFWQGIAFPD SAVVQQGCRN CSCTAGLWQC
1360 1370 1380 1390 1400
VPTAEPCPAQ PHCPDSEFPC RSGGRCVPGA WLCDNEDDCG DGSDEVCALH
1410 1420 1430 1440 1450
CAPHQHRCAD GQCVPWGARC DGLSDCGDGS DERGCPPPPC APPEFRCASG
1460 1470 1480 1490 1500
RCIPRAHVCN GELDCGFADD SDEAGCSPSC SVGEFQCAAG RCVPYPHRCN
1510 1520 1530 1540 1550
GHDDCGDFSD ERGCVCPAGH FQCPDAQCLP PAALCDGMQD CGDGTDEAFC
1560 1570 1580 1590 1600
PDRITCAPGQ LPCPDGSCVS QVKLCDGIWD CRDGWDESSV RCMVSWAPPA
1610 1620 1630 1640 1650
PTQLPTVPAN GTAAPVCGPY EFPCRSGQCV PRGWVCDSEA DCPDNSDELG
1660 1670 1680 1690 1700
CNRSCVLGHF PCALGAHCIH YDHLCDGIPH CPDHSDESDD NCGSTQIPPC
1710 1720 1730 1740 1750
PGHFVCNNRV CVNATRVCDG ALDCPQGEDE LACEGYVPTG ERNQTVGPCA
1760 1770 1780 1790 1800
EYSCRDGDCI TFKQVCNGLP DCRDGDMASG WLPSDEWDCG QWGPWAPWGI
1810 1820 1830 1840 1850
CSHSCGLGQQ LRARECSQRT PGVLHQCHGE ATQARPCFST ACPVDGAWSE
1860 1870 1880 1890 1900
WTMWSNCTQG CEGVVVRQRH CQPPRDGGRP CAALPATAHA TLEIGTCQQD
1910 1920 1930 1940 1950
GCPPASCPGG LQPRPCAPCP ASCADLASRA PCRREQCTPG CWCAEGLVLD
1960 1970 1980 1990 2000
GERGCVRPRE CRCEVDGLRY WPGQRMKLNC RLCTCLDGQP RRCRHNPACS
2010 2020 2030 2040 2050
VSCSWSAWSP WGECLGPCGV QSIQWSFRSP SHPGKHGTNR QCRGIYRKAR
2060 2070 2080 2090 2100
RCQTEPCQEC EHQGRSRAQG DRWRWGPCHV CQCLPGPEVR CSPYCARSAV
2110 2120 2130 2140 2150
GCPQGQVLVE GKGDSCCFCA QIGDNVTAIP TALTMEPPST MPGEPSDSPL
2160 2170 2180 2190 2200
PTFPLPSPGD PCYSPLGIAS LPDSSFTASA EQQQHPARAA RLHHVSPGLE
2210 2220 2230 2240 2250
LQGWAPPADT VPGLPSHLPF LQLDLLQTTN LTGVVVQGAG AGDAFITAFQ
2260 2270 2280 2290 2300
LQFSTDGNRW HNYQQLFQGN WDATTPVVQP LDHMVQARYI RILPQGFHNA
2310 2320 2330 2340 2350
IFLRAELLGC PTVPLDLAVT TAVTPAPCGT GEFWCGVSCV TASRRCDGAT
2360 2370 2380 2390 2400
DCPGGADEAG CEPPSSTTLP THPASLTTPG SAGILGLTAE PPVAPPAAVP
2410 2420 2430 2440 2450
EGTSAWLTVG STSPAVPSTT GLPGVPTATI TPRGPPSAGP PSPGMAAVTV
2460 2470 2480 2490 2500
SHPVMGPPAL PMPPTGVPTP TSAEPPLPRL LCPPDQFLCD ALGCVDAAMV
2510 2520 2530 2540 2550
CDGQQDCLDG SDEAHCGALP TSGSSPSPLA WPSSPPPTCS PKQFSCGTGE
2560 2570 2580 2590 2600
CLALEKRCDL SRDCADGSDE SSCADCILSP WGGWSQCSHS CGLGVTSRQR
2610 2620 2630 2640 2650
VLLRGALPGG TCHTPRLDTR ACFLRACPVP GAWAAWGVWS SCDAECGGGM
2660 2670 2680 2690 2700
RSRTRSCTDP PPKNGGQPCA GEALQSQPCN LQPCGDTREC GPGMVLVQEG
2710 2720 2730 2740 2750
DCVQGLVPPC PQVCGDLSAT SSCQSPCQEG CRCPPGLFLQ EGTCVNASQC
2760 2770 2780 2790 2800
HCHQGQQRWL PSQVFLRDGC SQCVCRDGVV TCEDTACPIA CAWSAWSLWT
2810 2820 2830 2840 2850
LCDRSCGVGM QERFRSPSNP AAANGGAPCD GDTREVRECH TPCATAEPSS
2860 2870 2880 2890 2900
GWSSWTPWSP CSRSCFHHVD QRGRRHRFRH CEGMGTCPGL GVQEEPCDTA
2910 2920 2930 2940 2950
PCPVAGVWMP WSAWSECSAP CDAGVQTRSR TCTPPAFGGA ECTGPHLQTR
2960 2970 2980 2990 3000
NCNTRPCGAQ CPDTMQYLTA EECRHSEGRC PWICQDLGAG VACTAQCQPG
3010 3020 3030 3040 3050
CHCPAGLLLQ NGTCVPPSHC LCHHRGHLYQ PGDINALDTC NNCTCVTGQM
3060 3070 3080 3090 3100
VCSTETCPVP CTWSNWTAWS TCSHSCDVGM RRRYRVPIVP PLAGGGPPCQ
3110 3120 3130 3140 3150
GPSMEVEFCS LQPCRAVAPW GPWSECSVSC GGGYRNRTRD GPPLHSLEFS
3160 3170 3180 3190 3200
TCNPAPCPGK EPGVCPPGKQ WQACAQGAAS CAELSAAPPA DGSCHPGCYC
3210 3220 3230 3240 3250
PPGALLLNNE CVAEAACPCA VDGVLYQPGD VVPQGCHNCS CIAGRVTNCS
3260 3270 3280 3290 3300
QEDCGDVDGP WTPWTPWSEC SASCGPGRQR RYRFCSAHPG VPCAEPQPQE
3310 3320 3330 3340 3350
RPCARQPCHS PDCAAVPGSV FSHCRPPCPR SCDDISHCVW HRQPGCYCTN
3360 3370 3380 3390 3400
GTLLDATGTA CVALENCTCL DAHSGQRHQP GQSVPRGDGC NNCTCTQGRL
3410 3420 3430 3440 3450
LCTGLPCPVP GAWCEWSPWT PCSRSCGDEA ATRHRVCSCP APQQGGAGCP
3460 3470 3480 3490 3500
GGLEGHGDTG MQLQHQECPS VPPCPEDGAW AAWGPWSGCG GCGGQAVRTR
3510 3520 3530 3540 3550
SCSSPPARFG GLPCAGEARQ SRACPWATSS CPECAGGLVA FTCGKPCPHS
3560 3570 3580 3590 3600
CEDLREDTAC MATPRCLPAC ACPHGQLLQD GDCVPPELCR CAWAPSKNGS
3610 3620 3630 3640 3650
IWEQDGAVPM QELQPGETVQ RHCQNCTCKS GTLQCHAEPG CRADGGWSPW
3660 3670 3680 3690 3700
GPWSPCSPGC QAGTQLASRQ CNNPTPQLGG RGCSGHSQRQ RPCPATEGCP
3710 3720 3730 3740 3750
EEEPWGEWSP WGPCSASCGG GEQLRHRDCP PPGGCPGLAL QSKTCNTHVC
3760 3770 3780 3790 3800
REAGCPPGRL YRECQQGEGC PYSCAHLAGR IACFPGGCQE GCHCPTGTLL
3810 3820 3830 3840 3850
HHGHCLQECP CVLTAEVLRK LRNSSADLQA APHLLGTRGP PLALDQELPP
3860 3870 3880 3890 3900
GSTIHSACTS CTCLHGRLNC SEPVCPRDGG FSPWGPWSSC SRSCGGLGVM
3910 3920 3930 3940 3950
TRRRGCTNPE PARGGRDCAG PRSDSKYCQS PECPAVPTTE PGPGVAGAEE
3960 3970 3980 3990 4000
EEGFGPWSPW SPCSKTCTHP ERPATKTRER PCVGTAVCSG DGFQEQPCNL
4010 4020 4030 4040 4050
PLCSDVPPCQ GEDCAGLNCS WAPWGPWTEC SRSCGVGRQQ RLRAYSPPGA
4060 4070 4080 4090 4100
SGRWCPGILS AFVQRRFCSL QACKVDGAWS AWSPWSRCDR TCGGGRAVRT
4110 4120 4130 4140 4150
RSCTRPPPKN GGQRCPGERH QLHLCNAQPC DDSCPPGMAL VTCANHCPRH
4160 4170 4180 4190 4200
CGDLQEGIVC REEEHCEPGC RCPNGTLEQD GGCVPLAHCE CTDAQGHGWV
4210 4220 4230 4240 4250
PGSTHHDGCN NCTCLEGRLR CTDRLCPPLR CPWSRWSRWS PCSVTCGDGQ
4260 4270 4280 4290 4300
QTRFRTPTAG SWDEECQGEQ MENRGCAAGP CPPLCPQGSW ERRLGDMWLQ
4310 4320 4330 4340 4350
GECQRCTCTP EGTVCEDTTC AGAEHCTWGT WSPCSRSCGT GLASREGSCP
4360 4370 4380 4390 4400
CPFPGPPGAV CNASTGDGAR PHREVQACYL RPCPAECSWS AWSSWGGCSC
4410 4420 4430 4440 4450
SSPLQHRYRH RHGTGLCVGL DVELHPCNTS GCSESSCEPP FEFQPCSPPC
4460 4470 4480 4490 4500
ARLCSTLQHP ELCPAQSHCL PGCFCPQGLL EQRSACVPPE QCDCLHTNES
4510 4520 4530 4540 4550
GDLVTLSPGD IILLGCKECV CQDGALQCSS EGCQGLLPLS PWSEWTPCST
4560 4570 4580 4590 4600
CLPLFPSHLG DATPHVSVQH RYRACLDPQS GQPWSGDTAV CSAELQQQRL
4610 4620 4630 4640 4650
CPDPDICQEL CLWSPWGPWG PCQQPCSGSF RLRHRHLQRL AGSGQCQGAQ
4660 4670 4680 4690 4700
TQSESCNTAV CPGEDCEKQG RVFATTCANS CPRACADLWQ HVECVQGGCK
4710 4720 4730 4740 4750
PGCRCPQGQL LQDGLCVPTA QCRCGLSGDN GTQELWPGQE ATIECHNCTC
4760 4770 4780 4790 4800
ENGTMVCPAL PCPSYGPWST WSPCSSSCGS GRTSRHRTCE PNPGGVPCMA
4810 4820 4830 4840 4850
SGMQETAECS PQPCPAGCQL SPWSPWSPCS SSCGGGRSER SRELLGGEEE
4860 4870 4880 4890 4900
PCPIPALRQH RVCNVHNCTQ ECPRSQVHRE CANACPHACA DLRPQTQCLP
4910 4920 4930 4940 4950
QPCQPGCACP PGQVLQDGAC VPPEECRCTL DSTMPGVLNL SREEQEQEHA
4960 4970 4980 4990 5000
PGSRLQHRCN TCICIRGTFN CSQEECNVDC LWSPWSPWSP CSVTCGMGER
5010 5020 5030 5040 5050
LSHRHPLRQR LYEGAECLGP PVRRAACHLP DCACPEGERW QGHEVPPGCE
5060 5070 5080 5090 5100
QSCRDILDET PANCTPSPSP GCTCEPGHYR NSSGHCVPST LCECLHQGQL
5110 5120 5130 5140 5150
HQPGSEWQEQ CARCRCVDGK ANCTDGCTPL SCPEGEVKVR EPGRCCPVCR
5160 5170 5180 5190 5200
MEWPEEPSSM CRRFTELRNI TKGPCSLPNV EVSFCSGRCP SRTAVTPEEP
5210 5220 5230 5240 5250
YLQTLCECCS YRLDPGSPVR ILSLPCAGGA AEPVVLPIIH SCECSSCQGG

DFSKR
Length:5,255
Mass (Da):560,556
Last modified:February 7, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDBE892EA9AA0378B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ866919 mRNA Translation: CAI29216.1

NCBI Reference Sequences

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RefSeqi
NP_001006351.2, NM_001006351.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
420367

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gga:420367

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ866919 mRNA Translation: CAI29216.1
RefSeqiNP_001006351.2, NM_001006351.2

3D structure databases

SMRiQ2PC93
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000007857

Proteomic databases

PaxDbiQ2PC93
PRIDEiQ2PC93

Genome annotation databases

GeneIDi420367
KEGGigga:420367

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
243369

Phylogenomic databases

eggNOGiKOG1215, Eukaryota
KOG1216, Eukaryota
KOG3611, Eukaryota
KOG4475, Eukaryota
InParanoidiQ2PC93
OrthoDBi12226at2759
PhylomeDBiQ2PC93

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q2PC93

Family and domain databases

CDDicd00057, FA58C, 1 hit
cd00112, LDLa, 12 hits
Gene3Di2.20.100.10, 23 hits
2.60.120.260, 1 hit
4.10.400.10, 13 hits
InterProiView protein in InterPro
IPR006207, Cys_knot_C
IPR000742, EGF-like_dom
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR036055, LDL_receptor-like_sf
IPR023415, LDLR_class-A_CS
IPR002172, LDrepeatLR_classA_rpt
IPR030119, SCO-spondin
IPR036084, Ser_inhib-like_sf
IPR002919, TIL_dom
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf
IPR014853, Unchr_dom_Cys-rich
IPR001007, VWF_dom
IPR001846, VWF_type-D
PANTHERiPTHR11339:SF358, PTHR11339:SF358, 8 hits
PfamiView protein in Pfam
PF00754, F5_F8_type_C, 1 hit
PF00057, Ldl_recept_a, 12 hits
PF01826, TIL, 12 hits
PF00090, TSP_1, 25 hits
PF00093, VWC, 1 hit
PF00094, VWD, 3 hits
PRINTSiPR00261, LDLRECEPTOR
SMARTiView protein in SMART
SM00832, C8, 3 hits
SM00181, EGF, 9 hits
SM00231, FA58C, 1 hit
SM00192, LDLa, 13 hits
SM00209, TSP1, 27 hits
SM00214, VWC, 9 hits
SM00215, VWC_out, 11 hits
SM00216, VWD, 3 hits
SUPFAMiSSF49785, SSF49785, 1 hit
SSF57424, SSF57424, 12 hits
SSF57567, SSF57567, 15 hits
SSF82895, SSF82895, 25 hits
PROSITEiView protein in PROSITE
PS01225, CTCK_2, 1 hit
PS01285, FA58C_1, 1 hit
PS01286, FA58C_2, 1 hit
PS50022, FA58C_3, 1 hit
PS01209, LDLRA_1, 11 hits
PS50068, LDLRA_2, 13 hits
PS50092, TSP1, 27 hits
PS01208, VWFC_1, 1 hit
PS50184, VWFC_2, 2 hits
PS51233, VWFD, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSPO_CHICK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2PC93
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: February 7, 2006
Last modified: August 12, 2020
This is version 90 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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