UniProtKB - Q2PBC2 (Q2PBC2_XENLA)
Protein
Submitted name:
G-protein coupled receptor
Gene
p2ry11.L
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
GO - Molecular functioni
- G protein-coupled ATP receptor activity Source: BHF-UCL
- G protein-coupled receptor activity Source: BHF-UCL
- neurotransmitter receptor activity Source: BHF-UCL
GO - Biological processi
- adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
- calcium-mediated signaling Source: BHF-UCL
- cellular response to ATP Source: BHF-UCL
- neuronal signal transduction Source: BHF-UCL
- purinergic nucleotide receptor signaling pathway Source: BHF-UCL
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotation, Receptor, Transducer |
Names & Taxonomyi
Protein namesi | Submitted name: G-protein coupled receptorImported |
Gene namesi | |
Organismi | Xenopus laevis (African clawed frog)Imported |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-6251851, p2ry11.L |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: BHF-UCL
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 20 – 40 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 52 – 76 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 100 – 123 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 135 – 154 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 178 – 202 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 222 – 243 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 32 – 285 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 254 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
OrthoDBi | 973156at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027677, P2Y11_rcpt |
PANTHERi | PTHR24231:SF46, PTHR24231:SF46, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q2PBC2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSVCNNSF GAVQTTFLAP MYGVAFVVSV LGNSLAIWLL GPGSSKNRHA
60 70 80 90 100
GIIFSLNLAV SDLFYSLSLP LLVAYYTMNK NWVFGLAMCK VERFVFNCNL
110 120 130 140 150
YGSIFFITCI SANRYLGIVF PFYTRGRVES KHAKWVSLGV WVLVAAISAP
160 170 180 190 200
VFLFSKLQVE NNKTECLGTA VNSELPSYFP YSLFLAGFGC ALPFLITFLS
210 220 230 240 250
YIGIAKAVWK SHGLEPREKR KVVTLVCVVV LLYAISFVPY HILRNLNLKN
260 270 280 290 300
RIATSDCKWS LKIHSAFQVA KALVSLNPCI HPLLYTAVID NVRAKLGCYQ
310
ESQDVKSQGE SRL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC169544 mRNA Translation: AAI69544.1 AM040941 mRNA Translation: CAJ13841.1 |
RefSeqi | NP_001089146.1, NM_001095677.1 |
Genome annotation databases
GeneIDi | 734177 |
KEGGi | xla:734177 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC169544 mRNA Translation: AAI69544.1 AM040941 mRNA Translation: CAJ13841.1 |
RefSeqi | NP_001089146.1, NM_001095677.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
GPCRDBi | Search... |
Genome annotation databases
GeneIDi | 734177 |
KEGGi | xla:734177 |
Organism-specific databases
CTDi | 734177 |
Xenbasei | XB-GENE-6251851, p2ry11.L |
Phylogenomic databases
OrthoDBi | 973156at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027677, P2Y11_rcpt |
PANTHERi | PTHR24231:SF46, PTHR24231:SF46, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q2PBC2_XENLA | |
Accessioni | Q2PBC2Primary (citable) accession number: Q2PBC2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 7, 2006 |
Last sequence update: | February 7, 2006 | |
Last modified: | December 2, 2020 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |