Putative ATP-dependent RNA helicase DHX30

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: UniProtKB-KW
• ATP-dependent RNA helicase activity Source: GO_Central
• chromatin binding Source: UniProtKB
• RNA binding Source: GO_Central

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• mitochondrial large ribosomal subunit assembly Source: UniProtKB
• RNA processing Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMⁱ

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Motif

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MATARRLMAL AAGVSPRLRP LGPRAIGRQG GPRGLSTGCS RPDRTQEAAE 
        60         70         80         90        100
AEAAPGEPGE GDGSVVNASR DLLKEFPQPK NLLNSVIGRA LGISHAKDKL 
       110        120        130        140        150
VYVHTNGPKK KKVTLHIKWP KSVEVEGYGS KKIDAERQAA AAACQLFKGW 
       160        170        180        190        200
GLLGPRNELF DAAKYRVLAD RFGSPADSWW RPEPTMPPTS WRQLNPESIR 
       210        220        230        240        250
PGGPGGLSRS LGREEEEDEE EELEEGTIDV TEFLSMTQQD SHAPLRDSRG 
       260        270        280        290        300
GSFEMTDDDS AIRALTQFPL PKNLLAKVIQ IATSSSTAKN LMQFHTVGTK 
       310        320        330        340        350
TKLSTLTLLW PCPMTFVAKG RRKAEAENKA AALACNKLKS LGLVDRNNEP 
       360        370        380        390        400
LTHAMYNLAS LRELGETQRR PCTIQVPEPI LRKIETFLNH YPVESSWISS 
       410        420        430        440        450
ELRLQGEDIL PLGKDSGPLS DPITGKPYVP LSEAEELRLS QSLLELWRRR 
       460        470        480        490        500
GPVWQEAPQL PVDPHRDTIL NAIEQHPVVV IAGDTGCGKT TRIPQLLLER 
       510        520        530        540        550
YVTEGRGARC NVIITQPRRI SAVSVAQRVS HELGPTLRRN VGFQVRLESK 
       560        570        580        590        600
PPARGGALLF CTVGILLRKL QSNPSLEGVS HVVVDEEHER DVNTDFLLIL 
       610        620        630        640        650
LKGLQRLNPA LRLVLMSATG DNERFSRYFG GCPVIKVPGF MYPVKEHYLE 
       660        670        680        690        700
DILAKLGKHQ YPHRHRHHES EDECALDLDL VTDLVLHIDA RGEPGGILCF 
       710        720        730        740        750
LPGWQEIKGV QQRLQEALGM HESKYLILPV HSNIPMMDQK AIFQQPPIGV 
       760        770        780        790        800
RKIVLATNIA ETSITINDIV HVVDSGLHKE ERYDLKTKVS CLETVWVSRA 
       810        820        830        840        850
NVIQRRGRAG RCQSGFAYHL FPRSRLEKMA PFQVPEILRT PLENLVLQAK 
       860        870        880        890        900
IHMPEKTAVE FLSKAVDSPN IKAVDEAVIL LQEIGVLDQR EYLTTLGQRL 
       910        920        930        940        950
AHISTDPRLA KAIVLAAIFR CLHPLLVVVS CLTRDPFSSS LQNRAEVDKV 
       960        970        980        990       1000
KALLSHDSGS DHLAFVRAVS GWEEVLRWQD RSSRENYLEE NLLYAPSLRF 
      1010       1020       1030       1040       1050
IHGLIKQFSE NIYEAFLVGK PSDCTLASAQ CNEYSEEEEL VKGVLMAGLY 
      1060       1070       1080       1090       1100
PNLIQVRQGK VTRQGKFKPN SVTYRTKSGN ILLHKSTINR EATRLRSRWL 
      1110       1120       1130       1140       1150
TYFMAVKSNG SVFVRDSSQV HPLAVLLLTD GDVHIRDDGR RATISLSDSD 
      1160       1170       1180       1190       1200
LLRLEGDSRT VRLLRELRRA LGRMVERSLR SELAALPPCV QEEHGQLLAL 
      1210       1220
LAELLRGPCG SFDVRKTADD                                  

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. SIMILARITY comments
   Index of protein domains and families