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Protein

Protein BUD31 homolog

Gene

BUD31

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

ReactomeiR-BTA-72163 mRNA Splicing - Major Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BUD31 homolog
Alternative name(s):
Protein G10 homolog
Gene namesi
Name:BUD31
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Organism-specific databases

VGNCiVGNC:26609 BUD31

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002498541 – 144Protein BUD31 homologAdd BLAST144

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei125N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ2NKU3
PRIDEiQ2NKU3

Expressioni

Gene expression databases

BgeeiENSBTAG00000020439 Expressed in 9 organ(s), highest expression level in testis

Interactioni

Subunit structurei

Identified in the spliceosome C complex. May interact with AR.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000036979

Structurei

3D structure databases

ProteinModelPortaliQ2NKU3
SMRiQ2NKU3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni59 – 67Interaction with ARBy similarity9

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi2 – 10Nuclear localization signalSequence analysis9

Domaini

Contains a short sequence motif (Phe-Xaa-Xaa-Phe-Tyr) that can bind to AR and may modulate AR activity.By similarity

Sequence similaritiesi

Belongs to the BUD31 (G10) family.Curated

Phylogenomic databases

eggNOGiKOG3404 Eukaryota
COG5132 LUCA
GeneTreeiENSGT00390000014300
HOGENOMiHOG000235066
HOVERGENiHBG080938
InParanoidiQ2NKU3
KOiK12873
OMAiCRGCSSD
OrthoDBiEOG091G0PEI
TreeFamiTF105609

Family and domain databases

InterProiView protein in InterPro
IPR018230 BUD31/G10-rel_CS
IPR001748 G10
PANTHERiPTHR19411 PTHR19411, 1 hit
PfamiView protein in Pfam
PF01125 G10, 1 hit
PRINTSiPR00322 G10
PROSITEiView protein in PROSITE
PS00997 G10_1, 1 hit
PS00998 G10_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2NKU3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKVKRSRKA PPDGWELIEP TLDELDQKMR EAETEPHEGK RKVESLWPIF
60 70 80 90 100
RIHHQKTRYI FDLFYKRKAI SRELYEYCIK EGYADKNLIA KWKKQGYENL
110 120 130 140
CCLRCIQTRD TNFGTNCICR VPKSKLEVGR IIECTHCGCR GCSG
Length:144
Mass (Da):17,000
Last modified:February 7, 2006 - v1
Checksum:i520B8E74C97D0926
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111638 mRNA Translation: AAI11639.1
BC142096 mRNA Translation: AAI42097.1
RefSeqiNP_001039829.1, NM_001046364.2
XP_005225221.1, XM_005225164.1
XP_005225222.1, XM_005225165.3
XP_005225223.1, XM_005225166.3
XP_005225224.1, XM_005225167.3
XP_005225225.1, XM_005225168.3
XP_015315969.1, XM_015460483.1
UniGeneiBt.4537

Genome annotation databases

EnsembliENSBTAT00000037140; ENSBTAP00000036979; ENSBTAG00000020439
GeneIDi533977
KEGGibta:533977

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111638 mRNA Translation: AAI11639.1
BC142096 mRNA Translation: AAI42097.1
RefSeqiNP_001039829.1, NM_001046364.2
XP_005225221.1, XM_005225164.1
XP_005225222.1, XM_005225165.3
XP_005225223.1, XM_005225166.3
XP_005225224.1, XM_005225167.3
XP_005225225.1, XM_005225168.3
XP_015315969.1, XM_015460483.1
UniGeneiBt.4537

3D structure databases

ProteinModelPortaliQ2NKU3
SMRiQ2NKU3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000036979

Proteomic databases

PaxDbiQ2NKU3
PRIDEiQ2NKU3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000037140; ENSBTAP00000036979; ENSBTAG00000020439
GeneIDi533977
KEGGibta:533977

Organism-specific databases

CTDi8896
VGNCiVGNC:26609 BUD31

Phylogenomic databases

eggNOGiKOG3404 Eukaryota
COG5132 LUCA
GeneTreeiENSGT00390000014300
HOGENOMiHOG000235066
HOVERGENiHBG080938
InParanoidiQ2NKU3
KOiK12873
OMAiCRGCSSD
OrthoDBiEOG091G0PEI
TreeFamiTF105609

Enzyme and pathway databases

ReactomeiR-BTA-72163 mRNA Splicing - Major Pathway

Gene expression databases

BgeeiENSBTAG00000020439 Expressed in 9 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR018230 BUD31/G10-rel_CS
IPR001748 G10
PANTHERiPTHR19411 PTHR19411, 1 hit
PfamiView protein in Pfam
PF01125 G10, 1 hit
PRINTSiPR00322 G10
PROSITEiView protein in PROSITE
PS00997 G10_1, 1 hit
PS00998 G10_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBUD31_BOVIN
AccessioniPrimary (citable) accession number: Q2NKU3
Secondary accession number(s): A5PJG0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: February 7, 2006
Last modified: September 12, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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