UniProtKB - Q2MD59 (Q2MD59_HUMAN)
Protein
Submitted name:
B-cell linker protein
Gene
BLNK
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: B-cell linker proteinImported |
Gene namesi | |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:14211, BLNK |
VEuPathDBi | HostDB:ENSG00000095585.16 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: HPA
Other locations
- cytoplasmic ribonucleoprotein granule Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000095585, Expressed in mouth mucosa and 205 other tissues |
ExpressionAtlasi | Q2MD59, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 36 – 185 | DisorderedSequence analysisAdd BLAST | 150 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 58 – 76 | AcidicSequence analysisAdd BLAST | 19 | |
Compositional biasi | 151 – 166 | PolarSequence analysisAdd BLAST | 16 |
Phylogenomic databases
GeneTreei | ENSGT00940000155715 |
Family and domain databases
InterProi | View protein in InterPro IPR036860, SH2_dom_sf |
SUPFAMi | SSF55550, SSF55550, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q2MD59-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR
60 70 80 90 100
DYASESPADE EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP
110 120 130 140 150
VEQETRPVHP ALPFARGTAS GRNSGAWETK SPPPAAPSPL PRAGKKPTTP
160 170 180 190 200
LKTTPVASQQ NASSVCEEKP IPAERHRGSS HRQEAVQSPV FPPAQKQIHQ
210 220 230 240 250
KPIPLPRFTE GGNPTVDGPL PSFSSNSTIS EQEAGVLCKP WYAGACDRKS
260 270 280 290
AEEALHRSNK YFGSVAEIIR NHQHSPLVLI DSQNNTKDST RLKYAVKVS
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8WV28 | BLNK_HUMAN | B-cell linker protein | BLNK BASH, SLP65 | 456 | Annotation score: | ||
Q2MD47 | Q2MD47_HUMAN | B-cell linker protein | BLNK BASH, SLP65 | 121 | Annotation score: | ||
K7EKR2 | K7EKR2_HUMAN | B-cell linker protein | BLNK | 65 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC021037 Genomic DNA No translation available. KF455281 Genomic DNA No translation available. KF573679 Genomic DNA No translation available. AM180327 mRNA Translation: CAJ55321.1 |
RefSeqi | NP_001245371.1, NM_001258442.1 |
Genome annotation databases
Ensembli | ENST00000427367; ENSP00000391924; ENSG00000095585 |
GeneIDi | 29760 |
UCSCi | uc001klv.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC021037 Genomic DNA No translation available. KF455281 Genomic DNA No translation available. KF573679 Genomic DNA No translation available. AM180327 mRNA Translation: CAJ55321.1 |
RefSeqi | NP_001245371.1, NM_001258442.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | Q2MD59 |
ProteomicsDBi | 24505 |
Protocols and materials databases
Antibodypediai | 3990, 720 antibodies |
DNASUi | 29760 |
Genome annotation databases
Ensembli | ENST00000427367; ENSP00000391924; ENSG00000095585 |
GeneIDi | 29760 |
UCSCi | uc001klv.5, human |
Organism-specific databases
CTDi | 29760 |
HGNCi | HGNC:14211, BLNK |
OpenTargetsi | ENSG00000095585 |
VEuPathDBi | HostDB:ENSG00000095585.16 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155715 |
Miscellaneous databases
BioGRID-ORCSi | 29760, 8 hits in 986 CRISPR screens |
ChiTaRSi | BLNK, human |
GenomeRNAii | 29760 |
Gene expression databases
Bgeei | ENSG00000095585, Expressed in mouth mucosa and 205 other tissues |
ExpressionAtlasi | Q2MD59, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR036860, SH2_dom_sf |
SUPFAMi | SSF55550, SSF55550, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q2MD59_HUMAN | |
Accessioni | Q2MD59Primary (citable) accession number: Q2MD59 Secondary accession number(s): F5GXS1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 21, 2006 |
Last sequence update: | February 21, 2006 | |
Last modified: | April 7, 2021 | |
This is version 92 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |