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Protein
Submitted name:

INVS protein

Gene

INVS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
INVS proteinImported
Gene namesi
Name:INVSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ2M1I4
PRIDEiQ2M1I4

Structurei

3D structure databases

ProteinModelPortaliQ2M1I4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 548ANK_REP_REGIONInterPro annotationAdd BLAST536
Repeati47 – 79ANKPROSITE-ProRule annotationAdd BLAST33
Repeati80 – 112ANKPROSITE-ProRule annotationAdd BLAST33
Repeati148 – 180ANKPROSITE-ProRule annotationAdd BLAST33
Repeati220 – 240ANKPROSITE-ProRule annotationAdd BLAST21
Repeati254 – 286ANKPROSITE-ProRule annotationAdd BLAST33
Repeati288 – 320ANKPROSITE-ProRule annotationAdd BLAST33
Repeati356 – 388ANKPROSITE-ProRule annotationAdd BLAST33
Repeati389 – 421ANKPROSITE-ProRule annotationAdd BLAST33
Repeati422 – 454ANKPROSITE-ProRule annotationAdd BLAST33
Repeati455 – 487ANKPROSITE-ProRule annotationAdd BLAST33
Repeati488 – 520ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili578 – 612Sequence analysisAdd BLAST35

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
HOGENOMiHOG000234066
HOVERGENiHBG083788

Family and domain databases

CDDicd00204 ANK, 4 hits
Gene3Di1.25.40.20, 4 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000048 IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 6 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 15 hits
SUPFAMiSSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 11 hits
PS50096 IQ, 1 hit

Sequencei

Sequence statusi: Complete.

Q2M1I4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKSENLLFA GSSLASQVHA AAVNGDKGAL QRLIVGNSAL KDKEDQFGRT
60 70 80 90 100
PLMYCVLADR LDCADALLKA GADVNKTDHS QRTALHLAAQ KGNYRFMKLL
110 120 130 140 150
LTRRANWMQK DLEEMTPLHL TTRHRSPKCL ALLLKFMAPG EVDTQDKNKQ
160 170 180 190 200
TALHWSAYYN NPEHVKLLIK HDSNIGIPDV EGKIPLHWAA NHKDPSAVHT
210 220 230 240 250
VRCILDAAPT ESLLNWQDYE GRTPLHFAVA DGNVTVVDVL TSYESCNITS
260 270 280 290 300
YDNLFRTPLH WAALLGHAQI VHLLLERNKS GTIPSDSQGA TPLHYAAQSN
310 320 330 340 350
FAETVKVFLK HPSVKDDSDL EGRTSFMWAA GKGSDDVLRT MLSLKSDIDI
360 370 380 390 400
NMADKYGGTA LHAAALSGHV STVKLLLENN AQVDATDVMK HTPLFRACEM
410 420 430 440 450
GHKDVIQTLI KGGARVDLVD QDGHSLLHWA ALGGNADVCQ ILIENKINPN
460 470 480 490 500
VQDYAGRTPL QCAAYGGYIN CMAVLMENNA DPNIQDKEGR TALHWSCNNG
510 520 530 540 550
YLDAIKLLLD FAAFPNQMEN NEERYTPLDY ALLGERHEVI QFMLEHGALS
560 570 580 590 600
IAAIQDIAAF KIQAVYKGYK VRKAFRDRKN LLMKHEQLRK DAAAKKREEE
610 620 630 640 650
NKRKEAEQQK GRRSPDSCRP QALPCLPSTQ DVPSRQSRAP SKQPPAGNVA
660 670 680 690 700
QGPEPRDSRG SPGGSLGGAL QKEQHVSSDL QGTNSRRPND PMKAVMEAGI
710 720
QEFPLLRSPE VRQLAMSGVQ RGKAS
Length:725
Mass (Da):80,010
Last modified:February 21, 2006 - v1
Checksum:i957245E46A9616D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112351 mRNA Translation: AAI12352.1
RefSeqiNP_001305310.1, NM_001318381.1
UniGeneiHs.558477
Hs.655024
Hs.742075

Genome annotation databases

GeneIDi27130

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112351 mRNA Translation: AAI12352.1
RefSeqiNP_001305310.1, NM_001318381.1
UniGeneiHs.558477
Hs.655024
Hs.742075

3D structure databases

ProteinModelPortaliQ2M1I4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ2M1I4
PRIDEiQ2M1I4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi27130

Organism-specific databases

CTDi27130

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
HOGENOMiHOG000234066
HOVERGENiHBG083788

Miscellaneous databases

ChiTaRSiINVS human
GenomeRNAii27130

Family and domain databases

CDDicd00204 ANK, 4 hits
Gene3Di1.25.40.20, 4 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000048 IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 6 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 15 hits
SUPFAMiSSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 11 hits
PS50096 IQ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ2M1I4_HUMAN
AccessioniPrimary (citable) accession number: Q2M1I4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: February 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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