UniProtKB - Q2L6M5 (Q2L6M5_DUGJA)
Protein
Innexin
Gene
inx10
Organism
Dugesia japonica (Planarian)
Status
Functioni
Structural component of the gap junctions.UniRule annotation
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Biological processi
- ion transport Source: UniProtKB-KW
Keywordsi
Molecular function | Ion channelUniRule annotation |
Biological process | Ion transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: InnexinUniRule annotation |
Gene namesi | Name:inx10Imported Synonyms:inxUniRule annotation |
Organismi | Dugesia japonica (Planarian)Imported |
Taxonomic identifieri | 6161 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Rhabditophora › Seriata › Tricladida › Continenticola › Geoplanoidea › Dugesiidae › Dugesia |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Other locations
- gap junction UniRule annotationARBA annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- gap junction Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 105 – 122 | HelicalPROSITE-ProRule annotationAdd BLAST | 18 | |
Transmembranei | 200 – 224 | HelicalPROSITE-ProRule annotationAdd BLAST | 25 | |
Transmembranei | 295 – 319 | HelicalPROSITE-ProRule annotationAdd BLAST | 25 |
Keywords - Cellular componenti
Cell junction, Gap junctionPROSITE-ProRule annotationARBA annotation, MembraneFamily & Domainsi
Sequence similaritiesi
Belongs to the pannexin family.PROSITE-ProRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPROSITE-ProRule annotationARBA annotationFamily and domain databases
InterProi | View protein in InterPro IPR000990, Innexin |
PANTHERi | PTHR11893, PTHR11893, 1 hit |
Pfami | View protein in Pfam PF00876, Innexin, 1 hit |
PRINTSi | PR01262, INNEXIN |
PROSITEi | View protein in PROSITE PS51013, PANNEXIN, 1 hit |
i Sequence
Sequence statusi: Complete.
Q2L6M5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESLLTQFSA FKVEKYVGIE DGADKASFLF SVAILAVCSI IISTKQYVTT
60 70 80 90 100
DISCYIPIVV SGSDFEKFIR NYCWVHGTIP FRSNESLPQT KEEWMTAEYT
110 120 130 140 150
RKINYYQWVP FVLGLQGVLF YLPRLIWRTI IYNLSGNHLE GLVVSAQKAT
160 170 180 190 200
NQVGDNRKET IEQIAKSLED LFLQRRVLGH KKFPVLRQKM SLVCCGRRTG
210 220 230 240 250
IFLVSLYFVI KILYLINAIG QILLMQNFLR LGTTKLNVAF GWTILHDIIS
260 270 280 290 300
GKQWTENLLF PRTTFCFIGD ISLVAVKNHF VAQCTLPINM LNEKIYIFLW
310 320 330 340 350
FWTVGVLILT LISIPLWLWR MTFFSKRQKF VKKFLKIKCS YSKGKHKELM
360 370 380 390 400
SHFVERFLRH DGIFILHIIS LNAGDLIAAD VVTELWQIYT KYYVERDFSK
410
NVISIIDEKT NQSFV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB189259 mRNA Translation: BAE78818.1 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB189259 mRNA Translation: BAE78818.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
InterProi | View protein in InterPro IPR000990, Innexin |
PANTHERi | PTHR11893, PTHR11893, 1 hit |
Pfami | View protein in Pfam PF00876, Innexin, 1 hit |
PRINTSi | PR01262, INNEXIN |
PROSITEi | View protein in PROSITE PS51013, PANNEXIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q2L6M5_DUGJA | |
Accessioni | Q2L6M5Primary (citable) accession number: Q2L6M5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 7, 2006 |
Last sequence update: | March 7, 2006 | |
Last modified: | February 10, 2021 | |
This is version 25 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |