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Entry version 131 (17 Jun 2020)
Sequence version 1 (07 Mar 2006)
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Protein
Submitted name:

HLA class I histocompatibility antigen B alpha chain

Gene

HLA-B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HLA class I histocompatibility antigen B alpha chainImported
Submitted name:
HLA class I histocompatibility antigen, B alpha chainImported
Submitted name:
Leukocyte antigen (HLA) class I moleculeImported
Submitted name:
Lymphocyte antigenImported
Submitted name:
MHC class I antigenImported
Submitted name:
MHC class I proteinImported
Submitted name:
Major histocompatibility complex, class I, BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HLA-BImported
Synonyms:HLA-B*4403Imported, HLA-B*44031Imported, HLA-B*44032Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4932 HLA-B

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei308 – 330HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501509729125 – 362Sequence analysisAdd BLAST338

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini209 – 295Ig-likeInterPro annotationAdd BLAST87

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni337 – 362DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi339 – 362PolarSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
3.30.500.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01638 MHCCLASSI

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00407 IGc1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 25 potential isoforms that are computationally mapped.Show allAlign All

Q2L6G2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVTAPRTLL LLLWGAVALT ETWAGSHSMR YFYTAMSRPG RGEPRFITVG
60 70 80 90 100
YVDDTLFVRF DSDATSPRKE PRAPWIEQEG PEYWDRETQI SKTNTQTYRE
110 120 130 140 150
NLRTALRYYN QSEAGSHIIQ RMYGCDVGPD GRLLRGYDQD AYDGKDYIAL
160 170 180 190 200
NEDLSSWTAA DTAAQITQRK WEAARVAEQL RAYLEGLCVE SLRRYLENGK
210 220 230 240 250
ETLQRADPPK THVTHHPISD HEVTLRCWAL GFYPAEITLT WQRDGEDQTQ
260 270 280 290 300
DTELVETRPA GDRTFQKWAA VVVPSGEEQR YTCHVQHEGL PKPLTLRWEP
310 320 330 340 350
SSQSTVPIVG IVAGLAVLAV VVIGAVVAAV MCRRKSSGGK GGSYSQAACS
360
DSAQGSDVSL TA
Length:362
Mass (Da):40,479
Last modified:March 7, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i41D1F475EFCE2E9B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 25 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P01889HLAB_HUMAN
HLA class I histocompatibility anti...
HLA-B HLAB
362Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5SS57Q5SS57_HUMAN
HLA class I antigen
HLA-B MICA
362Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S6AU73S6AU73_HUMAN
HLA class I histocompatibility anti...
HLA-B HLA B
362Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PPR8A0A1W2PPR8_HUMAN
HLA class I histocompatibility anti...
HLA-B
363Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D5H3J5D5H3J5_HUMAN
HLA class I histocompatibility anti...
HLA-B
362Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D9J307D9J307_HUMAN
HLA class I antigen
HLA-B
362Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9G0A0A140T9G0_HUMAN
HLA class I histocompatibility anti...
HLA-B
241Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9S9A0A140T9S9_HUMAN
HLA class I histocompatibility anti...
HLA-B
241Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T951A0A140T951_HUMAN
HLA class I histocompatibility anti...
HLA-B
241Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T9A9A0A140T9A9_HUMAN
HLA class I histocompatibility anti...
HLA-B
241Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX927178 Genomic DNA No translation available.
L42282 Genomic DNA Translation: AAB51454.1
L42283 Genomic DNA Translation: AAB51455.1
GQ161932 Genomic DNA Translation: ACS37219.1
GQ161933 Genomic DNA Translation: ACS37220.1
KT819314 Genomic DNA Translation: AMO26200.1
KU639956 Genomic DNA Translation: AMP83990.1
KT893445 Genomic DNA Translation: AMR70984.1
KU319295 Genomic DNA Translation: ANG08710.1
KY486786 Genomic DNA Translation: ASE99664.1
KY419489 Genomic DNA Translation: ASU50380.1
KY419490 Genomic DNA Translation: ASU50381.1
KY419491 Genomic DNA Translation: ASU50382.1
KY419492 Genomic DNA Translation: ASU50383.1
MG553984 Genomic DNA Translation: AUQ35641.1
MG680155 Genomic DNA Translation: AUT12116.1
MH173365 Genomic DNA Translation: AWM62417.1
MH347625 Genomic DNA Translation: AWM62531.1
MH294523 Genomic DNA Translation: AWW18850.1
MG905202 Genomic DNA Translation: AYE21466.1
MK005632 Genomic DNA Translation: AZL48703.1
MK005633 Genomic DNA Translation: AZL48704.1
MK058665 Genomic DNA Translation: AZL48730.1
MK257829 Genomic DNA Translation: AZU90055.1
MK300374 Genomic DNA Translation: AZU90096.1
MK308933 Genomic DNA Translation: AZU90187.1
MK336309 Genomic DNA Translation: AZU90246.1
AB202107 Genomic DNA Translation: BAE78632.1
LC257731 Genomic DNA Translation: BBD34049.1
LC326175 Genomic DNA Translation: BBD74411.1
X64366 mRNA Translation: CAA45718.1
LN810148 Genomic DNA Translation: CEO87025.1
LN868255 Genomic DNA Translation: CRX74686.1
LN877299 Genomic DNA Translation: CUA55042.1
LN877326 Genomic DNA Translation: CUA55069.1
LN877359 Genomic DNA Translation: CUA55102.1
LN877362 Genomic DNA Translation: CUA55105.1
MH269351 Genomic DNA Translation: QAX33611.1
MK394229 Genomic DNA Translation: QBM15482.1
MK689950 Genomic DNA Translation: QCQ66867.1
MK814908 Genomic DNA Translation: QDC33463.1
MK938030 Genomic DNA Translation: QDK62513.1
MK938034 Genomic DNA Translation: QDK62517.1
MK938039 Genomic DNA Translation: QDK62522.1
MK938040 Genomic DNA Translation: QDK62523.1
MK938043 Genomic DNA Translation: QDK62526.1
MK938062 Genomic DNA Translation: QDK62545.1
MN003041 Genomic DNA Translation: QDK62570.1
MN003046 Genomic DNA Translation: QDK62575.1
MN003056 Genomic DNA Translation: QDK62585.1
MN003060 Genomic DNA Translation: QDK62589.1
MN003061 Genomic DNA Translation: QDK62590.1
MN003062 Genomic DNA Translation: QDK62591.1
MN003063 Genomic DNA Translation: QDK62592.1
MN003064 Genomic DNA Translation: QDK62593.1
MN003077 Genomic DNA Translation: QDK62606.1
MN003082 Genomic DNA Translation: QDK62611.1
MN003086 Genomic DNA Translation: QDK62615.1
MN003088 Genomic DNA Translation: QDK62617.1
MN003103 Genomic DNA Translation: QDK62632.1
MN003109 Genomic DNA Translation: QDK62638.1
MN003127 Genomic DNA Translation: QDK62656.1
MN003136 Genomic DNA Translation: QDK62665.1
MN003137 Genomic DNA Translation: QDK62666.1
MN003156 Genomic DNA Translation: QDK62685.1
MN003157 Genomic DNA Translation: QDK62686.1
MN003171 Genomic DNA Translation: QDK62700.1
MN003183 Genomic DNA Translation: QDK62712.1
MN003184 Genomic DNA Translation: QDK62713.1
MN003187 Genomic DNA Translation: QDK62716.1
MN003189 Genomic DNA Translation: QDK62718.1
MN003207 Genomic DNA Translation: QDK62736.1
MN003212 Genomic DNA Translation: QDK62741.1
MN003222 Genomic DNA Translation: QDK62751.1
MN003223 Genomic DNA Translation: QDK62752.1
MN003232 Genomic DNA Translation: QDK62761.1
MN003235 Genomic DNA Translation: QDK62764.1
MN003253 Genomic DNA Translation: QDK62781.1
MN003262 Genomic DNA Translation: QDK62790.1
MN003278 Genomic DNA Translation: QDK62806.1
MN003304 Genomic DNA Translation: QDK62832.1
MN003312 Genomic DNA Translation: QDK62840.1
MN003328 Genomic DNA Translation: QDK62856.1
MN003330 Genomic DNA Translation: QDK62858.1
MN003333 Genomic DNA Translation: QDK62861.1
MN003349 Genomic DNA Translation: QDK62877.1
MN016191 Genomic DNA Translation: QDK62887.1
MN016219 Genomic DNA Translation: QDK62915.1
MN016229 Genomic DNA Translation: QDK62925.1
MN016231 Genomic DNA Translation: QDK62927.1
MN016235 Genomic DNA Translation: QDK62931.1
MN016248 Genomic DNA Translation: QDK62944.1
MN016255 Genomic DNA Translation: QDK62951.1
MN016261 Genomic DNA Translation: QDK62957.1
MN016275 Genomic DNA Translation: QDK62971.1
MN016314 Genomic DNA Translation: QDK63009.1
MN016322 Genomic DNA Translation: QDK63017.1
MN016333 Genomic DNA Translation: QDK63028.1
MN016338 Genomic DNA Translation: QDK63033.1
MN016342 Genomic DNA Translation: QDK63037.1
MN016353 Genomic DNA Translation: QDK63048.1
MN016355 Genomic DNA Translation: QDK63050.1
MN016356 Genomic DNA Translation: QDK63051.1
MN016366 Genomic DNA Translation: QDK63061.1
MN016390 Genomic DNA Translation: QDK63085.1
MN016397 Genomic DNA Translation: QDK63092.1
MN016404 Genomic DNA Translation: QDK63099.1
MN016405 Genomic DNA Translation: QDK63100.1
MN016409 Genomic DNA Translation: QDK63104.1
MN016410 Genomic DNA Translation: QDK63105.1
MN016417 Genomic DNA Translation: QDK63112.1
MN016421 Genomic DNA Translation: QDK63116.1
MN016425 Genomic DNA Translation: QDK63120.1
MN016428 Genomic DNA Translation: QDK63123.1
MN016431 Genomic DNA Translation: QDK63126.1
MN016437 Genomic DNA Translation: QDK63132.1
MN016448 Genomic DNA Translation: QDK63143.1
MN016459 Genomic DNA Translation: QDK63154.1
MN016462 Genomic DNA Translation: QDK63157.1
MN016465 Genomic DNA Translation: QDK63160.1
MN016467 Genomic DNA Translation: QDK63162.1
MN016472 Genomic DNA Translation: QDK63167.1
MN016490 Genomic DNA Translation: QDK63185.1
MN016492 Genomic DNA Translation: QDK63187.1
MN016494 Genomic DNA Translation: QDK63189.1
MN115487 Genomic DNA Translation: QDK63273.1
MN136804 Genomic DNA Translation: QDK63307.1
MN136805 Genomic DNA Translation: QDK63308.1
MN166924 Genomic DNA Translation: QEQ28503.1
MK757470 Genomic DNA Translation: QFR55279.1
MK947431 Genomic DNA Translation: QGV11029.1
MN735228 Genomic DNA Translation: QHQ71354.1
MN735270 Genomic DNA Translation: QHQ71396.1
MN227125 Genomic DNA Translation: QIB00640.1
LT599219 Genomic DNA Translation: SBW38440.1
LT599262 Genomic DNA Translation: SBW38483.1
LT962594 Genomic DNA Translation: SOQ60065.1
LT962598 Genomic DNA Translation: SOQ60069.1
LT962611 Genomic DNA Translation: SOQ60082.1
LT963270 Genomic DNA Translation: SOR74814.1
LT963281 Genomic DNA Translation: SOR74825.1
LS398654 Genomic DNA Translation: SPR56213.1
LS398669 Genomic DNA Translation: SPR56228.1
LS423057 Genomic DNA Translation: SPS03164.1
LS480864 Genomic DNA Translation: SPT23703.1
LR027031 Genomic DNA Translation: VCU43071.1
LR027055 Genomic DNA Translation: VCU43095.1
LR027061 Genomic DNA Translation: VCU43101.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000435618; ENSP00000405178; ENSG00000224608

UCSC genome browser

More...
UCSCi
uc011gwy.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX927178 Genomic DNA No translation available.
L42282 Genomic DNA Translation: AAB51454.1
L42283 Genomic DNA Translation: AAB51455.1
GQ161932 Genomic DNA Translation: ACS37219.1
GQ161933 Genomic DNA Translation: ACS37220.1
KT819314 Genomic DNA Translation: AMO26200.1
KU639956 Genomic DNA Translation: AMP83990.1
KT893445 Genomic DNA Translation: AMR70984.1
KU319295 Genomic DNA Translation: ANG08710.1
KY486786 Genomic DNA Translation: ASE99664.1
KY419489 Genomic DNA Translation: ASU50380.1
KY419490 Genomic DNA Translation: ASU50381.1
KY419491 Genomic DNA Translation: ASU50382.1
KY419492 Genomic DNA Translation: ASU50383.1
MG553984 Genomic DNA Translation: AUQ35641.1
MG680155 Genomic DNA Translation: AUT12116.1
MH173365 Genomic DNA Translation: AWM62417.1
MH347625 Genomic DNA Translation: AWM62531.1
MH294523 Genomic DNA Translation: AWW18850.1
MG905202 Genomic DNA Translation: AYE21466.1
MK005632 Genomic DNA Translation: AZL48703.1
MK005633 Genomic DNA Translation: AZL48704.1
MK058665 Genomic DNA Translation: AZL48730.1
MK257829 Genomic DNA Translation: AZU90055.1
MK300374 Genomic DNA Translation: AZU90096.1
MK308933 Genomic DNA Translation: AZU90187.1
MK336309 Genomic DNA Translation: AZU90246.1
AB202107 Genomic DNA Translation: BAE78632.1
LC257731 Genomic DNA Translation: BBD34049.1
LC326175 Genomic DNA Translation: BBD74411.1
X64366 mRNA Translation: CAA45718.1
LN810148 Genomic DNA Translation: CEO87025.1
LN868255 Genomic DNA Translation: CRX74686.1
LN877299 Genomic DNA Translation: CUA55042.1
LN877326 Genomic DNA Translation: CUA55069.1
LN877359 Genomic DNA Translation: CUA55102.1
LN877362 Genomic DNA Translation: CUA55105.1
MH269351 Genomic DNA Translation: QAX33611.1
MK394229 Genomic DNA Translation: QBM15482.1
MK689950 Genomic DNA Translation: QCQ66867.1
MK814908 Genomic DNA Translation: QDC33463.1
MK938030 Genomic DNA Translation: QDK62513.1
MK938034 Genomic DNA Translation: QDK62517.1
MK938039 Genomic DNA Translation: QDK62522.1
MK938040 Genomic DNA Translation: QDK62523.1
MK938043 Genomic DNA Translation: QDK62526.1
MK938062 Genomic DNA Translation: QDK62545.1
MN003041 Genomic DNA Translation: QDK62570.1
MN003046 Genomic DNA Translation: QDK62575.1
MN003056 Genomic DNA Translation: QDK62585.1
MN003060 Genomic DNA Translation: QDK62589.1
MN003061 Genomic DNA Translation: QDK62590.1
MN003062 Genomic DNA Translation: QDK62591.1
MN003063 Genomic DNA Translation: QDK62592.1
MN003064 Genomic DNA Translation: QDK62593.1
MN003077 Genomic DNA Translation: QDK62606.1
MN003082 Genomic DNA Translation: QDK62611.1
MN003086 Genomic DNA Translation: QDK62615.1
MN003088 Genomic DNA Translation: QDK62617.1
MN003103 Genomic DNA Translation: QDK62632.1
MN003109 Genomic DNA Translation: QDK62638.1
MN003127 Genomic DNA Translation: QDK62656.1
MN003136 Genomic DNA Translation: QDK62665.1
MN003137 Genomic DNA Translation: QDK62666.1
MN003156 Genomic DNA Translation: QDK62685.1
MN003157 Genomic DNA Translation: QDK62686.1
MN003171 Genomic DNA Translation: QDK62700.1
MN003183 Genomic DNA Translation: QDK62712.1
MN003184 Genomic DNA Translation: QDK62713.1
MN003187 Genomic DNA Translation: QDK62716.1
MN003189 Genomic DNA Translation: QDK62718.1
MN003207 Genomic DNA Translation: QDK62736.1
MN003212 Genomic DNA Translation: QDK62741.1
MN003222 Genomic DNA Translation: QDK62751.1
MN003223 Genomic DNA Translation: QDK62752.1
MN003232 Genomic DNA Translation: QDK62761.1
MN003235 Genomic DNA Translation: QDK62764.1
MN003253 Genomic DNA Translation: QDK62781.1
MN003262 Genomic DNA Translation: QDK62790.1
MN003278 Genomic DNA Translation: QDK62806.1
MN003304 Genomic DNA Translation: QDK62832.1
MN003312 Genomic DNA Translation: QDK62840.1
MN003328 Genomic DNA Translation: QDK62856.1
MN003330 Genomic DNA Translation: QDK62858.1
MN003333 Genomic DNA Translation: QDK62861.1
MN003349 Genomic DNA Translation: QDK62877.1
MN016191 Genomic DNA Translation: QDK62887.1
MN016219 Genomic DNA Translation: QDK62915.1
MN016229 Genomic DNA Translation: QDK62925.1
MN016231 Genomic DNA Translation: QDK62927.1
MN016235 Genomic DNA Translation: QDK62931.1
MN016248 Genomic DNA Translation: QDK62944.1
MN016255 Genomic DNA Translation: QDK62951.1
MN016261 Genomic DNA Translation: QDK62957.1
MN016275 Genomic DNA Translation: QDK62971.1
MN016314 Genomic DNA Translation: QDK63009.1
MN016322 Genomic DNA Translation: QDK63017.1
MN016333 Genomic DNA Translation: QDK63028.1
MN016338 Genomic DNA Translation: QDK63033.1
MN016342 Genomic DNA Translation: QDK63037.1
MN016353 Genomic DNA Translation: QDK63048.1
MN016355 Genomic DNA Translation: QDK63050.1
MN016356 Genomic DNA Translation: QDK63051.1
MN016366 Genomic DNA Translation: QDK63061.1
MN016390 Genomic DNA Translation: QDK63085.1
MN016397 Genomic DNA Translation: QDK63092.1
MN016404 Genomic DNA Translation: QDK63099.1
MN016405 Genomic DNA Translation: QDK63100.1
MN016409 Genomic DNA Translation: QDK63104.1
MN016410 Genomic DNA Translation: QDK63105.1
MN016417 Genomic DNA Translation: QDK63112.1
MN016421 Genomic DNA Translation: QDK63116.1
MN016425 Genomic DNA Translation: QDK63120.1
MN016428 Genomic DNA Translation: QDK63123.1
MN016431 Genomic DNA Translation: QDK63126.1
MN016437 Genomic DNA Translation: QDK63132.1
MN016448 Genomic DNA Translation: QDK63143.1
MN016459 Genomic DNA Translation: QDK63154.1
MN016462 Genomic DNA Translation: QDK63157.1
MN016465 Genomic DNA Translation: QDK63160.1
MN016467 Genomic DNA Translation: QDK63162.1
MN016472 Genomic DNA Translation: QDK63167.1
MN016490 Genomic DNA Translation: QDK63185.1
MN016492 Genomic DNA Translation: QDK63187.1
MN016494 Genomic DNA Translation: QDK63189.1
MN115487 Genomic DNA Translation: QDK63273.1
MN136804 Genomic DNA Translation: QDK63307.1
MN136805 Genomic DNA Translation: QDK63308.1
MN166924 Genomic DNA Translation: QEQ28503.1
MK757470 Genomic DNA Translation: QFR55279.1
MK947431 Genomic DNA Translation: QGV11029.1
MN735228 Genomic DNA Translation: QHQ71354.1
MN735270 Genomic DNA Translation: QHQ71396.1
MN227125 Genomic DNA Translation: QIB00640.1
LT599219 Genomic DNA Translation: SBW38440.1
LT599262 Genomic DNA Translation: SBW38483.1
LT962594 Genomic DNA Translation: SOQ60065.1
LT962598 Genomic DNA Translation: SOQ60069.1
LT962611 Genomic DNA Translation: SOQ60082.1
LT963270 Genomic DNA Translation: SOR74814.1
LT963281 Genomic DNA Translation: SOR74825.1
LS398654 Genomic DNA Translation: SPR56213.1
LS398669 Genomic DNA Translation: SPR56228.1
LS423057 Genomic DNA Translation: SPS03164.1
LS480864 Genomic DNA Translation: SPT23703.1
LR027031 Genomic DNA Translation: VCU43071.1
LR027055 Genomic DNA Translation: VCU43095.1
LR027061 Genomic DNA Translation: VCU43101.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENST00000435618; ENSP00000405178; ENSG00000224608
UCSCiuc011gwy.3 human

Organism-specific databases

HGNCiHGNC:4932 HLA-B

GenAtlas: human gene database

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GenAtlasi
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Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
HLA-B human

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ2L6G2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2L6G2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: June 17, 2020
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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