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Protein

Cyclin-dependent kinases regulatory subunit 2

Gene

CKS2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunit 2
Short name:
CKS-2
Gene namesi
Name:CKS2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 8

Organism-specific databases

VGNCiVGNC:27388 CKS2

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002604471 – 79Cyclin-dependent kinases regulatory subunit 2Add BLAST79

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei4N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ2KJI1

Expressioni

Gene expression databases

BgeeiENSBTAG00000001938

Interactioni

Subunit structurei

Forms a homohexamer that can probably bind six kinase subunits.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002522

Structurei

3D structure databases

ProteinModelPortaliQ2KJI1
SMRiQ2KJI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.Curated

Phylogenomic databases

eggNOGiKOG3484 Eukaryota
ENOG4111UAN LUCA
GeneTreeiENSGT00390000011006
HOVERGENiHBG003626
InParanoidiQ2KJI1
KOiK02219
OMAiNPEPHVL
OrthoDBiEOG091G18GQ
TreeFamiTF101142

Family and domain databases

Gene3Di3.30.170.10, 1 hit
InterProiView protein in InterPro
IPR000789 Cyclin-dep_kinase_reg-sub
IPR036858 Cyclin-dep_kinase_reg-sub_sf
PfamiView protein in Pfam
PF01111 CKS, 1 hit
PRINTSiPR00296 CYCLINKINASE
SMARTiView protein in SMART
SM01084 CKS, 1 hit
SUPFAMiSSF55637 SSF55637, 1 hit
PROSITEiView protein in PROSITE
PS00944 CKS_1, 1 hit
PS00945 CKS_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q2KJI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHKQIYYSD KYFDEHYEYR HVMLPRELSK QVPKTHLMSE EEWRRLGVQQ
60 70
SLGWVHYMIH EPEPHILLFR RPLPKDQQK
Length:79
Mass (Da):9,860
Last modified:March 7, 2006 - v1
Checksum:i811B5927691EEC5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105331 mRNA Translation: AAI05332.1
RefSeqiNP_001106790.1, NM_001113319.2
UniGeneiBt.13573

Genome annotation databases

EnsembliENSBTAT00000002522; ENSBTAP00000002522; ENSBTAG00000001938
GeneIDi767985
KEGGibta:767985

Similar proteinsi

Entry informationi

Entry nameiCKS2_BOVIN
AccessioniPrimary (citable) accession number: Q2KJI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 7, 2006
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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