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Protein

RING finger protein 151

Gene

RNF151

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in acrosome formation of spermatids.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri20 – 58RING-typePROSITE-ProRule annotationAdd BLAST39
Zinc fingeri101 – 156TRAF-typePROSITE-ProRule annotationAdd BLAST56

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDifferentiation, Spermatogenesis
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RING finger protein 151
Gene namesi
Name:RNF151
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000179580.9
HGNCiHGNC:23235 RNF151
neXtProtiNX_Q2KHN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179580
PharmGKBiPA134992556

Polymorphism and mutation databases

BioMutaiRNF151
DMDMi119371030

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002552541 – 245RING finger protein 151Add BLAST245

Proteomic databases

PaxDbiQ2KHN1
PeptideAtlasiQ2KHN1
PRIDEiQ2KHN1
ProteomicsDBi61304

PTM databases

iPTMnetiQ2KHN1
PhosphoSitePlusiQ2KHN1

Expressioni

Gene expression databases

BgeeiENSG00000179580 Expressed in 75 organ(s), highest expression level in right testis
CleanExiHS_RNF151
ExpressionAtlasiQ2KHN1 baseline and differential
GenevisibleiQ2KHN1 HS

Interactioni

Subunit structurei

Interacts with DTNBP1.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
NKAPD1Q6ZUT14EBI-12002474,EBI-3920396

Protein-protein interaction databases

BioGridi126977, 57 interactors
IntActiQ2KHN1, 15 interactors
STRINGi9606.ENSP00000456566

Structurei

3D structure databases

ProteinModelPortaliQ2KHN1
SMRiQ2KHN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri20 – 58RING-typePROSITE-ProRule annotationAdd BLAST39
Zinc fingeri101 – 156TRAF-typePROSITE-ProRule annotationAdd BLAST56

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410KDGV Eukaryota
ENOG4111KUV LUCA
GeneTreeiENSGT00530000063647
HOGENOMiHOG000154154
HOVERGENiHBG087956
InParanoidiQ2KHN1
OMAiCKKCILQ
OrthoDBiEOG091G0NOP
PhylomeDBiQ2KHN1
TreeFamiTF351947

Family and domain databases

Gene3Di3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR008974 TRAF-like
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
IPR013010 Znf_SIAH
IPR001293 Znf_TRAF
SMARTiView protein in SMART
SM00184 RING, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
PS51081 ZF_SIAH, 1 hit
PS50145 ZF_TRAF, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q2KHN1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGGYDLNLF ASPPDSNFVC SVCHGVLKRP ARLPCSHIFC KKCILRWLAR
60 70 80 90 100
QKTCPCCRKE VKRKKVVHMN KLRKTIGRLE VKCKNADAGC IVTCPLAHRK
110 120 130 140 150
GHQDSCPFEL TACPNEGCTS QVPRGTLAEH RQHCQQGSQQ RCPLGCGATL
160 170 180 190 200
DPAERARHNC YRELHNAWSV RQERRRPLLL SLLRRVRWLD QATSVVRREL
210 220 230 240
AELSNFLEED TALLEGAPQE EAEAAPEGNV GAEVVGEPRA NIPCK
Length:245
Mass (Da):27,412
Last modified:March 7, 2006 - v1
Checksum:iD96AF6A1B7DDD755
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DFQ4A0A0C4DFQ4_HUMAN
RING finger protein 151
RNF151
244Annotation score:
H3BNJ8H3BNJ8_HUMAN
RING finger protein 151
RNF151
90Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029501 mRNA Translation: AAH29501.2
BC113014 mRNA Translation: AAI13015.1
CCDSiCCDS58405.1
RefSeqiNP_001335640.1, NM_001348711.1
NP_777563.2, NM_174903.5
UniGeneiHs.99354

Genome annotation databases

EnsembliENST00000569714; ENSP00000456566; ENSG00000179580
GeneIDi146310
KEGGihsa:146310
UCSCiuc002cnt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC029501 mRNA Translation: AAH29501.2
BC113014 mRNA Translation: AAI13015.1
CCDSiCCDS58405.1
RefSeqiNP_001335640.1, NM_001348711.1
NP_777563.2, NM_174903.5
UniGeneiHs.99354

3D structure databases

ProteinModelPortaliQ2KHN1
SMRiQ2KHN1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126977, 57 interactors
IntActiQ2KHN1, 15 interactors
STRINGi9606.ENSP00000456566

PTM databases

iPTMnetiQ2KHN1
PhosphoSitePlusiQ2KHN1

Polymorphism and mutation databases

BioMutaiRNF151
DMDMi119371030

Proteomic databases

PaxDbiQ2KHN1
PeptideAtlasiQ2KHN1
PRIDEiQ2KHN1
ProteomicsDBi61304

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000569714; ENSP00000456566; ENSG00000179580
GeneIDi146310
KEGGihsa:146310
UCSCiuc002cnt.1 human

Organism-specific databases

CTDi146310
EuPathDBiHostDB:ENSG00000179580.9
GeneCardsiRNF151
HGNCiHGNC:23235 RNF151
neXtProtiNX_Q2KHN1
OpenTargetsiENSG00000179580
PharmGKBiPA134992556
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410KDGV Eukaryota
ENOG4111KUV LUCA
GeneTreeiENSGT00530000063647
HOGENOMiHOG000154154
HOVERGENiHBG087956
InParanoidiQ2KHN1
OMAiCKKCILQ
OrthoDBiEOG091G0NOP
PhylomeDBiQ2KHN1
TreeFamiTF351947

Miscellaneous databases

GenomeRNAii146310
PROiPR:Q2KHN1

Gene expression databases

BgeeiENSG00000179580 Expressed in 75 organ(s), highest expression level in right testis
CleanExiHS_RNF151
ExpressionAtlasiQ2KHN1 baseline and differential
GenevisibleiQ2KHN1 HS

Family and domain databases

Gene3Di3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR008974 TRAF-like
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
IPR013010 Znf_SIAH
IPR001293 Znf_TRAF
SMARTiView protein in SMART
SM00184 RING, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
PS51081 ZF_SIAH, 1 hit
PS50145 ZF_TRAF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRN151_HUMAN
AccessioniPrimary (citable) accession number: Q2KHN1
Secondary accession number(s): Q8NHS5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 7, 2006
Last modified: November 7, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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