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Entry version 113 (07 Apr 2021)
Sequence version 1 (07 Mar 2006)
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Protein

Cortactin-binding protein 2

Gene

Cttnbp2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • SH3 domain binding Source: RGD

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cortactin-binding protein 2
Short name:
CortBP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cttnbp2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4
  • UP000234681 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

Rat genome database

More...
RGDi
628691, Cttnbp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasm, Synapse

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004221731 – 1649Cortactin-binding protein 2Add BLAST1649

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei495Asymmetric dimethylarginineBy similarity1
Modified residuei1510PhosphoserineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q2IBD4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2IBD4

PRoteomics IDEntifications database

More...
PRIDEi
Q2IBD4

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q2IBD4

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q2IBD4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q2IBD4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000061845, Expressed in frontal cortex and 19 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2IBD4, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CTTN/cortactin SH3 domain.

Interacts with STRN, STRN4/zinedin and MOB4/phocein; this interaction may regulate dendritic spine distribution of STRN and STRN4 in hippocampal neurons. Activation of glutamate receptors weakens the interaction with STRN and STRN4.

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
251850, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000011135

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2IBD4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati699 – 729ANK 1Add BLAST31
Repeati733 – 762ANK 2Add BLAST30
Repeati766 – 795ANK 3Add BLAST30
Repeati799 – 828ANK 4Add BLAST30
Repeati832 – 861ANK 5Add BLAST30
Repeati901 – 931ANK 6Add BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili118 – 275Sequence analysisAdd BLAST158

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QWG2, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158293

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004926_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2IBD4

Identification of Orthologs from Complete Genome Data

More...
OMAi
AYQIAAC

Database of Orthologous Groups

More...
OrthoDBi
264951at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q2IBD4

TreeFam database of animal gene trees

More...
TreeFami
TF325130

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR019131, Cortactin-binding_p2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit
PF09727, CortBP2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q2IBD4-1) [UniParc]FASTAAdd to basket
Also known as: CTTNBP2-L

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATDSASCEP DLSRAPGDAE GATAEAAKKE FDVDTLSKSE LRMLLSVMEG
60 70 80 90 100
ELEARDLVIE ALRARRKEVF IQERYGRFNL NDPFLALQRD YEAGAGDKEK
110 120 130 140 150
PVCTNPLSIL EAVMAHCRKM QERMSAQLAA AESRQKKLEM EKLQLQALEQ
160 170 180 190 200
EHKKLAAHLE EERGKNKHVV LMLVKECKQL SGKVVEEAQK LEEVMVKLEE
210 220 230 240 250
EKKKTSELED QLSAEKQRSA GMEAQLEKQL FEFDTEREQL RAKLTREEAH
260 270 280 290 300
TTDLKEEIDK MKKMMEQMKK GNDGKPGLSL PRKTKDKRLA SISVATEGPV
310 320 330 340 350
TRSVACQTDV VTESTDPVKK LPLSVPIKPS TGSPLVSTNT KGNVGPSALL
360 370 380 390 400
IRPGIDRQAS HSDLGPSPPT ALPSSASRIE ENGPSAGNAP DLSNSTPSTP
410 420 430 440 450
SGTAPAAAQT LGAAPQNHSQ APPVHSLHSP CANTHPGLNP RIQAARFRFQ
460 470 480 490 500
GNANDPDQNG NNTQSPPSRD VSPTSRDNLV AKQLARNTVT QALSRFTSPQ
510 520 530 540 550
AGASSRLGAS PGGDAGTCPP VGRTGLKTPG AARVDRGNPP PIPPKKPGLS
560 570 580 590 600
QTPSPPHPQL RASNAGAKVD NKIVASPPST LPQGTKVVNE ENVPKSSSPQ
610 620 630 640 650
LPPKPSIDLT VASAGCPVSA LATSQVGAWP AETPGLNQPA CTDSSLVIPT
660 670 680 690 700
TVAFRSSINP VSASSRSPGA SDSLLVTASG WSPSLTPLLM SGGPAPLAGR
710 720 730 740 750
PTLLQQAAAQ GNVTLLSMLL NEEGLDINYC CEDSHSALYS AAKNGHTDCV
760 770 780 790 800
RLLLNAEARV DAADKNGFTP LCVAAAQGHF ECIELLTAYN ANINHSAAGG
810 820 830 840 850
QTPLYLACKT GNKECIKLLL EAGTDRSIKT RDGWTPIHAA VDTGNVDSLK
860 870 880 890 900
LLMYHRVPAP GNSLSAEEPK SGLFSLNGGE SPPGSSKPVV PADLINHADK
910 920 930 940 950
EGWTAAHIAA SKGFKNCLEI LCRHGGLEPE RRDKCNRTVH DVATDDCKHL
960 970 980 990 1000
LENLNALKIP LRISVGEIQP SNDGSDDFEC EHTICTLNIR KQTSWEDFSK
1010 1020 1030 1040 1050
AVSQALTNHF QAISSDGCWG LEDGTLNNTT DSCIGLGTSS IQSIMLGSIP
1060 1070 1080 1090 1100
WSTGQSFSQS PWDFMKKKKV EQVTVLLSGP QEGCLSSVTY TSMIPLQMLQ
1110 1120 1130 1140 1150
NYLRLVEQYH NVIFHGPEGS LQDYIANQLA LCMKHRQMAA GFPCEIVRAE
1160 1170 1180 1190 1200
VDSGFSKEQL VDVFISNACL IPVKQFPVKK KIIVILENLE KSSLSELLGD
1210 1220 1230 1240 1250
FLAPLENRST ESPCTFQKGN GTSECYYFHE NCFLLGTLAK ACLQGSDLLV
1260 1270 1280 1290 1300
QQHFRWVQLR WDCEPSQGLL QRFLRRKAVS KFRGQLPAPC DPVCKIVDWV
1310 1320 1330 1340 1350
ISVWRQLNSC LARLGTPEAL LGPKYFLSCP VVPGHAQATV KWMSKLWNAI
1360 1370 1380 1390 1400
IAPRVQEAIL SRAAMNKQPG ARQTASKKHP SQGQQAVVRA ALSILLNKAI
1410 1420 1430 1440 1450
LHGCPLPRTE LDQQIADFKG GSFPLSIVSS YSKKKGESAA WRKVNTSPRK
1460 1470 1480 1490 1500
KPGHFSSPMW NKPDLKHEGM RNKSVPHLNI NRSSSLSKQQ SLENDLSMTL
1510 1520 1530 1540 1550
TLDHRLSLGS DDEADLVKEL QSMCSSKSES DISKIADSRE DLRTFDSSRT
1560 1570 1580 1590 1600
NPVTSAPVNL RMPVPQKEAS PLSSHQTTEC SNSKSKTELG VSRVKSFLPV
1610 1620 1630 1640
PRSKVAQCSQ NTKRSSSSSS NTRQLEINNN SKEENWNVDK HEHVEKRNK
Length:1,649
Mass (Da):178,768
Last modified:March 7, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i12C85BF86EB2634B
GO
Isoform 2 (identifier: Q2IBD4-2) [UniParc]FASTAAdd to basket
Also known as: CTTNBP2-S

The sequence of this isoform differs from the canonical sequence as follows:
     626-630: VGAWP → AGHPP
     631-1649: Missing.

Show »
Length:630
Mass (Da):67,351
Checksum:iCE583C3D3DCBEE8E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti163R → K in AAC35911 (PubMed:9813110).Curated1
Sequence conflicti260K → Q in AAC35911 (PubMed:9813110).Curated1
Sequence conflicti280L → F in AAC35911 (PubMed:9813110).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_046479626 – 630VGAWP → AGHPP in isoform 2. 1 Publication5
Alternative sequenceiVSP_046480631 – 1649Missing in isoform 2. 1 PublicationAdd BLAST1019

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF053768 mRNA Translation: AAC35911.1
DP000027 Genomic DNA Translation: AAR16316.1
AC087251 Genomic DNA No translation available.
AC111378 Genomic DNA No translation available.
AC119088 Genomic DNA No translation available.
CH473959 Genomic DNA Translation: EDM15128.1

NCBI Reference Sequences

More...
RefSeqi
NP_001107873.1, NM_001114401.1 [Q2IBD4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000087167; ENSRNOP00000072761; ENSRNOG00000061845 [Q2IBD4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
282587

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:282587

UCSC genome browser

More...
UCSCi
RGD:628691, rat [Q2IBD4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053768 mRNA Translation: AAC35911.1
DP000027 Genomic DNA Translation: AAR16316.1
AC087251 Genomic DNA No translation available.
AC111378 Genomic DNA No translation available.
AC119088 Genomic DNA No translation available.
CH473959 Genomic DNA Translation: EDM15128.1
RefSeqiNP_001107873.1, NM_001114401.1 [Q2IBD4-1]

3D structure databases

SMRiQ2IBD4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi251850, 1 interactor
STRINGi10116.ENSRNOP00000011135

PTM databases

CarbonylDBiQ2IBD4
iPTMnetiQ2IBD4
PhosphoSitePlusiQ2IBD4

Proteomic databases

jPOSTiQ2IBD4
PaxDbiQ2IBD4
PRIDEiQ2IBD4

Genome annotation databases

EnsembliENSRNOT00000087167; ENSRNOP00000072761; ENSRNOG00000061845 [Q2IBD4-1]
GeneIDi282587
KEGGirno:282587
UCSCiRGD:628691, rat [Q2IBD4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83992
RGDi628691, Cttnbp2

Phylogenomic databases

eggNOGiENOG502QWG2, Eukaryota
GeneTreeiENSGT00940000158293
HOGENOMiCLU_004926_0_0_1
InParanoidiQ2IBD4
OMAiAYQIAAC
OrthoDBi264951at2759
PhylomeDBiQ2IBD4
TreeFamiTF325130

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q2IBD4

Gene expression databases

BgeeiENSRNOG00000061845, Expressed in frontal cortex and 19 other tissues
GenevisibleiQ2IBD4, RN

Family and domain databases

Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR019131, Cortactin-binding_p2_N
PfamiView protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit
PF09727, CortBP2, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 6 hits
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTTB2_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2IBD4
Secondary accession number(s): O88864
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: March 7, 2006
Last modified: April 7, 2021
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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