Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Suppressor of tumorigenicity 7 protein

Gene

St7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Suppressor of tumorigenicity 7 protein
Gene namesi
Name:St7
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1303148 ST7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 35HelicalSequence analysisAdd BLAST21
Transmembranei62 – 82HelicalSequence analysisAdd BLAST21
Transmembranei512 – 532HelicalSequence analysisAdd BLAST21
Transmembranei539 – 559HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003392151 – 577Suppressor of tumorigenicity 7 proteinAdd BLAST577

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi47N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei386PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiQ2IBD0
PRIDEiQ2IBD0

PTM databases

PhosphoSitePlusiQ2IBD0

Expressioni

Gene expression databases

BgeeiENSRNOG00000056243 Expressed in 9 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiQ2IBD0 baseline and differential

Structurei

3D structure databases

SMRiQ2IBD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ST7 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3807 Eukaryota
ENOG410XQ2Z LUCA
GeneTreeiENSGT00390000000873
HOGENOMiHOG000036528
HOVERGENiHBG054916
InParanoidiQ2IBD0
PhylomeDBiQ2IBD0
TreeFamiTF314162

Family and domain databases

CDDicd11557 ST7, 1 hit
Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR007311 ST7
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR12745 PTHR12745, 1 hit
PfamiView protein in Pfam
PF04184 ST7, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q2IBD0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEAGSGFLE QLKSCIVWSW TYLWTVWFFL VLFLVYILRV PLRINDNLST
60 70 80 90 100
VSMFLNTLTP KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH
110 120 130 140 150
LRPLLGGVDN NSSNNSNSSN GDSDSNRQSV SECKVWRNPL NLFRGAEYNR
160 170 180 190 200
YTWVTGREPL TYYDMNLSAQ DHQTFFTCDS DHLRPADAIM QKAWRERNPQ
210 220 230 240 250
ARISAAHEAL EINEIRSRVE VPLIASSTIW EIKLLPKCAT AYILLAEEEA
260 270 280 290 300
TTIAEAEKLF KQALKAGDGC YRRSQQLQHH GSQYEAQHRR DTNVLVYIKR
310 320 330 340 350
RLAMCARRLG RTREAVKMMR DLMKEFPLLS MFNIHENLLE ALLELQAYAD
360 370 380 390 400
VQAVLAKYDD ISLPKSATIC YTAALLKARA VSDKFSPEAA SRRGLSTAEM
410 420 430 440 450
NAVEAIHRAV EFNPHVPKYL LEMKSLILPP EHILKRGDSE AIAYAFFHLA
460 470 480 490 500
HWKRVEGALN LLHCTWEGTF RMIPYPLEKG HLFYPYPICT ETADRELLPS
510 520 530 540 550
FHEVSVYPKK ELPFFILFTA GLCSFTAMLA LLTHQFPELM GVFAKAFLST
560 570
LFAPLNFVME KVESILPSSL WHQLTRI
Length:577
Mass (Da):66,111
Last modified:March 7, 2006 - v1
Checksum:iE3256054BD796258
GO
Isoform 2 (identifier: Q2IBD0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     215-237: Missing.
     470-500: Missing.

Show »
Length:523
Mass (Da):59,800
Checksum:i68AB5E218E00E759
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q2IBC9Q2IBC9_RAT
Suppression of tumorigenicity 7
ST7 Capza2, Cav, Cav2, Cftr, LOC500040
554Annotation score:
A0A0G2JTJ1A0A0G2JTJ1_RAT
Suppression of tumorigenicity 7
ST7
528Annotation score:
A0A0G2KBB5A0A0G2KBB5_RAT
Suppression of tumorigenicity 7
ST7
511Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6S → A in AAH99820 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_034125215 – 237Missing in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_034126470 – 500Missing in isoform 2. 1 PublicationAdd BLAST31

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000027 Genomic DNA Translation: AAR16311.1
BC099820 mRNA Translation: AAH99820.1
RefSeqiXP_006236194.1, XM_006236132.3 [Q2IBD0-1]
UniGeneiRn.24435

Genome annotation databases

EnsembliENSRNOT00000084736; ENSRNOP00000071529; ENSRNOG00000056243 [Q2IBD0-2]
GeneIDi296911
UCSCiRGD:1303148 rat [Q2IBD0-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000027 Genomic DNA Translation: AAR16311.1
BC099820 mRNA Translation: AAH99820.1
RefSeqiXP_006236194.1, XM_006236132.3 [Q2IBD0-1]
UniGeneiRn.24435

3D structure databases

SMRiQ2IBD0
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSitePlusiQ2IBD0

Proteomic databases

PaxDbiQ2IBD0
PRIDEiQ2IBD0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000084736; ENSRNOP00000071529; ENSRNOG00000056243 [Q2IBD0-2]
GeneIDi296911
UCSCiRGD:1303148 rat [Q2IBD0-1]

Organism-specific databases

CTDi7982
RGDi1303148 ST7

Phylogenomic databases

eggNOGiKOG3807 Eukaryota
ENOG410XQ2Z LUCA
GeneTreeiENSGT00390000000873
HOGENOMiHOG000036528
HOVERGENiHBG054916
InParanoidiQ2IBD0
PhylomeDBiQ2IBD0
TreeFamiTF314162

Miscellaneous databases

PROiPR:Q2IBD0

Gene expression databases

BgeeiENSRNOG00000056243 Expressed in 9 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiQ2IBD0 baseline and differential

Family and domain databases

CDDicd11557 ST7, 1 hit
Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR007311 ST7
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR12745 PTHR12745, 1 hit
PfamiView protein in Pfam
PF04184 ST7, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiST7_RAT
AccessioniPrimary (citable) accession number: Q2IBD0
Secondary accession number(s): Q499P1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 7, 2006
Last modified: September 12, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again