Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 13 of 13  Show
  1. 1
    "Characterization of RACK7, a novel heterochromatin and mitotic chromosome associated protein."
    Grkovic S., Velasco G., Ansieau S.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 18418 other entries.

  3. 3
    "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
    Bailey S.D., Xie C., Do R., Montpetit A., Diaz R., Mohan V., Keavney B., Yusuf S., Gerstein H.C., Engert J.C., Anand S.
    Diabetes Care 33:2250-2253(2010) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 18329 other entries.

  4. 4
    "Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression."
    Kuroyanagi J., Shimada Y., Zhang B., Ariyoshi M., Umemoto N., Nishimura Y., Tanaka T.
    FEBS Lett. 588:3409-3416(2014) [PubMed] [Europe PMC] [Abstract]
    Annotation: ZMYND8 induces vegfa mRNA expression selectively in prostate cancer xenografts.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 22 other entries.

  5. 5
    "Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination."
    Gong F., Chiu L.Y., Cox B., Aymard F., Clouaire T., Leung J.W., Cammarata M., Perez M., Agarwal P., Brodbelt J.S., Legube G., Miller K.M.
    Genes Dev. 29:197-211(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: identified ZMYND8 (zinc finger and MYND [myeloid Nervy and DEAF-1]Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 6 other entries.

  6. 6
    "Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8."
    Adhikary S., Sanyal S., Basu M., Sengupta I., Sen S., Srivastava D.K., Roy S., Das C.
    J. Biol. Chem. 291:2664-2681(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: study identifies that ZMYND8 has CHD4-independent functions in regulating gene expression through its modified histone-binding ability.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 6 other entries.

  7. 7
    "Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex."
    Shen H., Xu W., Guo R., Rong B., Gu L., Wang Z., He C., Zheng L., Hu X., Hu Z., Shao Z.M., Yang P., Wu F., Shi Y.G., Shi Y., Lan F.
    Cell 165:331-342(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: Findings reveal a RACK7/KDM5C-regulated dynamic interchange between histone H3K4me1 and H3K4me3 at active enhancers representing an additional layer of regulation of enhancer activity. Authors propose that RACK7/KDM5C functions as an enhancer "brake" to ensure appropriate enhancer activity which when compromised could contribute to tumorigenesis.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 9 other entries.

  8. 8
    "ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes."
    Li N., Li Y., Lv J., Zheng X., Wen H., Shen H., Zhu G., Chen T.Y., Dhar S.S., Kan P.Y., Wang Z., Shiekhattar R., Shi X., Lan F., Chen K., Li W., Li H., Lee M.G.
    Mol. Cell 63:470-484(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: ZMYND8's PHD-Bromo cassette couples H3K4me1-H3K14ac with downregulation of metastasis-linked genes in prostate tumor cells.Imported.
    Source: GeneRIF:23613.

    This publication is cited by 1 and mapped to 5 other entries.

  9. 9
    "ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage."
    Spruijt C.G., Luijsterburg M.S., Menafra R., Lindeboom R.G., Jansen P.W., Edupuganti R.R., Baltissen M.P., Wiegant W.W., Voelker-Albert M.C., Matarese F., Mensinga A., Poser I., Vos H.R., Stunnenberg H.G., van Attikum H., Vermeulen M.
    Cell Rep 17:783-798(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: The MYND domain of ZMYND8 directly interacts with PPPLPhi motifs in the NuRD subunit GATAD2A.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 11 other entries.

  10. 10
    "Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin."
    Savitsky P., Krojer T., Fujisawa T., Lambert J.P., Picaud S., Wang C.Y., Shanle E.K., Krajewski K., Friedrichsen H., Kanapin A., Goding C., Schapira M., Samsonova A., Strahl B.D., Gingras A.C., Filippakopoulos P.
    Cell Rep 17:2724-2737(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: Single domain disruptions destroy the functional network of interactions initiated by ZMYND8 impairing recruitment to sites of DNA damage. Our data establish a proof of principle that rigidity can be compensated by concomitant DNA and histone post-translational-modifications (PTMs) interactions maintaining multivalent engagement of transient chromatin states.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 6 other entries.

  11. 11
    "Chromatin reader ZMYND8 is a key target of all trans retinoic acid-mediated inhibition of cancer cell proliferation."
    Basu M., Khan M.W., Chakrabarti P., Das C.
    Biochim. Biophys. Acta 1860:450-459(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: a dual histone reader ZMYND8 (zinc finger MYND (Myeloid Nervy and DEAF-1)-type containing 8) was identified to be a novel target of all trans retinoic acid.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 25 other entries.

  12. 12
    "Dual histone reader ZMYND8 inhibits cancer cell invasion by positively regulating epithelial genes."
    Basu M., Sengupta I., Khan M.W., Srivastava D.K., Chakrabarti P., Roy S., Das C.
    Biochem. J. 474:1919-1934(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: Data suggest that epithelial-mesenchymal transition (EMT) is regulated by ZMYND8 (receptor for activated protein kinase C) which selectively activates gene promoters of CLDN1 (claudin 1) and CDH1 (E-cadherin) in breast cancer cells; thus the presence of ZMYND8 could be implicated in maintaining epithelial phenotype of cells; ZMYND8 regulates invasion/migration of breast cancer cells.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 19 other entries.

  13. 13
    "Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair."
    Gong F., Clouaire T., Aguirrebengoa M., Legube G., Miller K.M.
    J. Cell Biol. 216:1959-1974(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: KDM5A demethylates H3K4 to allow ZMYND8-NuRD to operate within damaged chromatin to repair DNA double strand breaks.Imported.
    Source: GeneRIF:23613.

    This publication is mapped to 6 other entries.

1 to 13 of 13  Show

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health