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Entry version 59 (02 Jun 2021)
Sequence version 1 (15 May 2007)
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Protein

Large tegument protein deneddylase

Gene

ORF64

Organism
Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Large tegument protein that plays multiple roles in the viral cycle. During viral entry, remains associated with the capsid while most of the tegument is detached and participates in the capsid transport toward the host nucleus. Plays a role in the routing of the capsid at the nuclear pore complex and subsequent uncoating. Within the host nucleus, acts as a deneddylase and promotes the degradation of nuclear CRLs (cullin-RING ubiquitin ligases) and thereby stabilizes nuclear CRL substrates, while cytoplasmic CRLs remain unaffected. These modifications prevent host cell cycle S-phase progression and create a favorable environment allowing efficient viral genome replication. Participates later in the secondary envelopment of capsids. Indeed, plays a linker role for the association of the outer viral tegument to the capsids together with the inner tegument protein.

UniRule annotation1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).UniRule annotation EC:3.4.19.12

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei16Important for catalytic activityUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei29UniRule annotation1
Active sitei159UniRule annotation1
Active sitei161UniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processHost-virus interaction, Modulation of host ubiquitin pathway by viral deubiquitinase, Modulation of host ubiquitin pathway by virus, Ubl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Large tegument protein deneddylaseUniRule annotation (EC:3.4.19.12UniRule annotation, EC:3.4.22.-UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ORF64
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHuman herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri868565 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesDuplodnaviriaHeunggongviraePeploviricotaHerviviricetesHerpesviralesHerpesviridaeGammaherpesvirinaeRhadinovirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiHomo sapiens (Human) [TaxID: 9606]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000942 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Host cytoplasm, Host nucleus, Virion, Virion tegument

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004069141 – 2635Large tegument protein deneddylaseAdd BLAST2635

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q2HR64

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with host CUL1 and CUL4A; these interactions inhibit the E3 ligase activity of cullins.

Interacts with inner tegument protein.

Interacts with capsid vertex specific component CVC2.

Interacts with the major capsid protein/MCP.

UniRule annotation

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
1776944, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q2HR64, 3 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2HR64

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 223Peptidase C76UniRule annotationAdd BLAST215

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 233Deubiquitination activityUniRule annotationAdd BLAST233
Regioni243 – 497DisorderedSequence analysisAdd BLAST255
Regioni316 – 325Interaction with inner tegument proteinUniRule annotation10
Regioni2238 – 2269DisorderedSequence analysisAdd BLAST32
Regioni2357 – 2438DisorderedSequence analysisAdd BLAST82
Regioni2500 – 2533DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi243 – 259Polar residuesSequence analysisAdd BLAST17
Compositional biasi260 – 274Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi326 – 341Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi371 – 393Pro residuesSequence analysisAdd BLAST23
Compositional biasi428 – 442Polar residuesSequence analysisAdd BLAST15
Compositional biasi483 – 497Polar residuesSequence analysisAdd BLAST15
Compositional biasi2407 – 2421Pro residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the herpesviridae large tegument protein family.UniRule annotation

Keywords - Domaini

Repeat

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_04044, HSV_LTP, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006928, Herpes_teg_USP
IPR034702, HSV_LTP
IPR038765, Papain-like_cys_pep_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04843, Herpes_teg_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54001, SSF54001, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51521, HTUSP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2HR64-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAQPLYMEG MASTHQANCI FGEHAGSQCL SNCVMYLASS YYNSETPLVD
60 70 80 90 100
RASLDDVLEQ GMRLDLLLRK SGMLGFRQYA QLHHIPGFLR TDDWATKIFQ
110 120 130 140 150
SPEFYGLIGQ DAAIREPFIE SLRSVLSRNY AGTVQYLIII CQSKAGAIVV
160 170 180 190 200
KDKTYYMFDP HCIPNIPNSP AHVIKTNDVG VLLPYIATHD TEYTGCFLYF
210 220 230 240 250
IPHDYISPEH YIANHYRTIV FEELHGPRMD ISRGVESCSI TEITSPSVSP
260 270 280 290 300
APSEAPLRRD STQSQDETRP RRPRVVIPPY DPTDRPRPPH QDRPPEQAAG
310 320 330 340 350
YGGNKGRGGN KGRGGKTGRG GNEGRGGHQP PDEHQPPHIT AEHMDQSDGQ
360 370 380 390 400
GADGDMDSTP ANGETSVTET PGPEPNPPAR PDREPPPTPP ATPGATALLS
410 420 430 440 450
DLTATRGQKR KFSSLKESYP IDSPPSDDDD VSQPSQQTAP DTEDIWIDDP
460 470 480 490 500
LTPLYPLTDT PSFDITADVT PDNTHPEKAA DGDFTNKTTS TDADRYASAS
510 520 530 540 550
QESLGTLVSP YDFTNLDTLL AELGRLGTAQ PIPVIVDRLT SRPFREASAL
560 570 580 590 600
QAMDRILTHV VLEYGLVSGY STAAPSKCTH VLQFFILWGE KLGIPTEDAK
610 620 630 640 650
TLLESALEIP AMCEIVQQGR LKEPTFSRHI ISKLNPCLES LHATSRQDFK
660 670 680 690 700
SLIQAFNAEG IRIASRERET SMAELIETIT ARLKPNFNIV CARQDAQTIQ
710 720 730 740 750
DGVGLLRAEV NKRNAQIAQE AAYFENIITA LSTFQPPPQS QQTFEVLPDL
760 770 780 790 800
KLRTLVEHLT LVEAQVTTQT VESLQAYLQS AATAEHHLTN VPNVHSILSN
810 820 830 840 850
ISNTLKVIDY VIPKFIINTD TLAPYKQQFS YLGGELASMF SLDWPHAPAE
860 870 880 890 900
AVEPLPVLTS LRGKIAEALT RQENKNAVDQ ILTDAEGLLK NITDPNGAHF
910 920 930 940 950
HAQAVSIPVL ENYVHNAGVL LKGEKSERFS RLKTAIQNLV SSESFITVTL
960 970 980 990 1000
HSTNLGNLVT NVPKLGEAFT GGPHLLTSPS VRQSLSTLCT TLLRDALDAL
1010 1020 1030 1040 1050
EKKDPALLGE GTTLALETLL GYGSVQDYKE TVQIISSLVG IQKLVRDQGA
1060 1070 1080 1090 1100
DKWATAVTRL TDLKSTLATT AIETATKRKL YRLIQRDLKE AQKHETNRAM
1110 1120 1130 1140 1150
EEWKQKVLAL DNASPERVAT LLQQAPTAKA REFAEKHFKI LLPVPADAPV
1160 1170 1180 1190 1200
QASPTPMEYS ASPLPDPKDI DRATSIHGEQ AWKKIQQAFK DFNFAVLRPA
1210 1220 1230 1240 1250
DWDALAAEYQ RRGSPLPAAV GPALSGFLET ILGTLNDIYM DKLRSFLPDA
1260 1270 1280 1290 1300
QPFQAPPFDW LTPYQDQVSF FLRTIGLPLV RALADKISVQ ALRLSHALQS
1310 1320 1330 1340 1350
GDLQQATVGT PLELPATEYA RIASNMKSVF NDHGLQVRSE VADYVEAQRA
1360 1370 1380 1390 1400
DAHTPHVPRP KIQAPKTLIP HPDAIVADGL PAFLKTSLLQ QEAKLLALQR
1410 1420 1430 1440 1450
ADFESLESDM RAAEAQRKAS REETQRKMAH AITQLLQQAP SAISGRPLSL
1460 1470 1480 1490 1500
QDPVGFLEGI IYDKVLERES YETGLEGLSW LEQTIKSITV YAPVEEKQRM
1510 1520 1530 1540 1550
HVLLDEVKKQ RANTETALEL EAAATHGDDA RLLQRAVDEL SPLRVKGGKA
1560 1570 1580 1590 1600
AVESWRQKIQ TLKSLVQEAE QAGLLLATID TVAGQAQETI SPSTLQGLYQ
1610 1620 1630 1640 1650
QGQEAMAAIK RFRDSPQLAG LQEKLAELQQ YVKYKKQYLE HFEATQSVVF
1660 1670 1680 1690 1700
TAFPLTQEVT IPALHYAGPF DNLERLSRYL HIGQTQPAPG QWLLTLPTFD
1710 1720 1730 1740 1750
PTRPACVPAG GHEPPLHRQV VFSSFLEAQI RLALSVAGPV PGRGLPGTPQ
1760 1770 1780 1790 1800
IRRGVEAAAC FLHQWDEISR LLPEVLDTFF HNAPLPAESS SNAFLAMCVL
1810 1820 1830 1840 1850
THLVYLAGRA VLGPREPEHA APDAYPREVA LAPRDLTYLL LAMWPSWISA
1860 1870 1880 1890 1900
ILKQPSHAEA AHACLVTLPT MLKAVPYLTL EASAGPLPAD MRHFATPEAR
1910 1920 1930 1940 1950
LFFPARWHHV NVQEKLWLRN DFMSLCHRSP GRARIAVLVW AVTCLDPEVI
1960 1970 1980 1990 2000
RQLWSTLRPL TADESDTASG LLRVLVEMEF GPPPKTPRRE AVAPGATLPP
2010 2020 2030 2040 2050
YPYGLATGER LVGQAQERSG GAGKMPVSGF EIVLGALLFR APLRIFSTAS
2060 2070 2080 2090 2100
THRISDFEGG FQILTPLLDC CPDREPFASL AAAPRRTVPL GDPCANIHTP
2110 2120 2130 2140 2150
EEIQIFARQA AWLQYTFANY QIPSTDNPIP IVVLNANNNL ENSYIPRDRK
2160 2170 2180 2190 2200
ADPLRPFYVV PLKPQGRWPE IMTTATTPCR LPTSPEEAGS QFARLLQSQV
2210 2220 2230 2240 2250
SATWSDIFSR VPERLAPNAP QKSSQTMSEI HEVAATPPLT ITPNKPTGTP
2260 2270 2280 2290 2300
HVSPEADPIT ERKRGQQPKI VADNMPSRIL PSLPTPKPRE PRITLPHALP
2310 2320 2330 2340 2350
VISPPAHRPS PIPHLPAPQV TEPKGVLQSK RGTLVLRPAA VIDPRKPVSA
2360 2370 2380 2390 2400
PITRYERTAL QPPRTEGEGR RPPDTQPVTL TFRLPPTAPT PATAALETKT
2410 2420 2430 2440 2450
TPPSTPPHAI DISPPQTPPM STSPHARDTS PPAEKRAAPV IRVMAPTQPS
2460 2470 2480 2490 2500
GEARVKRVEI EQGLSTRNEA PPLERSNHAV PAVTPRRTVA REIRIPPEIK
2510 2520 2530 2540 2550
AGWDTAPDIP LPHSSPESSP PTSPQPIRVD DKSPLPNLVE RYARGFLDTP
2560 2570 2580 2590 2600
SVEVMSLENQ DIAVDPGLLT RRIPSVVPMP HPIMWSPIVP ISLQNTDIDT
2610 2620 2630
AKITLISFIR RIKQKVAALS ASLAETVDRI KKWYL
Length:2,635
Mass (Da):289,691
Last modified:May 15, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i00070132EA8139AF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF148805 Genomic DNA Translation: ABD28919.1

NCBI Reference Sequences

More...
RefSeqi
YP_001129421.1, NC_009333.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4961441

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:4961441

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF148805 Genomic DNA Translation: ABD28919.1
RefSeqiYP_001129421.1, NC_009333.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6PPBelectron microscopy4.30n/o1-2635[»]
6PPHelectron microscopy3.80n/o1-2635[»]
SMRiQ2HR64
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi1776944, 3 interactors
IntActiQ2HR64, 3 interactors

Proteomic databases

PRIDEiQ2HR64

Genome annotation databases

GeneIDi4961441
KEGGivg:4961441

Family and domain databases

HAMAPiMF_04044, HSV_LTP, 1 hit
InterProiView protein in InterPro
IPR006928, Herpes_teg_USP
IPR034702, HSV_LTP
IPR038765, Papain-like_cys_pep_sf
PfamiView protein in Pfam
PF04843, Herpes_teg_N, 1 hit
SUPFAMiSSF54001, SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS51521, HTUSP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLTP_HHV8P
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2HR64
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: May 15, 2007
Last modified: June 2, 2021
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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