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Protein

Metalloendopeptidase

Gene

nas-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • pharyngeal pumping Source: WormBase
  • pharynx development Source: WormBase

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
MetalloendopeptidaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:nas-6Imported
ORF Names:4R79.1Imported, CELE_4R79.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBasei4R79.1b ; CE39659 ; WBGene00003525 ; nas-6

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi136 ↔ 170PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiWBGene00003525 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Structurei

3D structure databases

ProteinModelPortaliQ2HQL9
SMRiQ2HQL9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini136 – 170ShKTInterPro annotationAdd BLAST35

Phylogenomic databases

eggNOGiKOG3714 Eukaryota
ENOG410ZPX7 LUCA
GeneTreeiENSGT00760000119227
HOGENOMiHOG000200198
OrthoDBiEOG091G009U

Family and domain databases

Gene3Di3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR001506 Peptidase_M12A
IPR003582 ShKT_dom
PfamiView protein in Pfam
PF01400 Astacin, 1 hit
PF01549 ShK, 1 hit
PRINTSiPR00480 ASTACIN
SMARTiView protein in SMART
SM00254 ShKT, 1 hit
PROSITEiView protein in PROSITE
PS51670 SHKT, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q2HQL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHSVGFWHEH SRADRDDHIK INWDNILPGM KSQFDKISAV LQDLQGENYD
60 70 80 90 100
YKSIMHYDST AFSRNGRNTI ETVENGFTQV IGTAMDLSPL DIVKINKLYS
110 120 130 140 150
CKTKKKEKVK PATTEEPHQL IPQVVDKNSV DSGEKCVDHF ADCPHFAQYC
160 170 180
TRASFFFVMK SYCPFTCKHC PGDRKLKKSG
Length:180
Mass (Da):20,611
Last modified:March 21, 2006 - v1
Checksum:i97501ADE44B936B5
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9U3S9NAS6_CAEEL
Zinc metalloproteinase nas-6
nas-6 4R79.1
344Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAJ76926.1
RefSeqiNP_001040903.1, NM_001047438.2
UniGeneiCel.13675

Genome annotation databases

EnsemblMetazoai4R79.1b; 4R79.1b; WBGene00003525
GeneIDi181796
UCSCi4R79.1a c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAJ76926.1
RefSeqiNP_001040903.1, NM_001047438.2
UniGeneiCel.13675

3D structure databases

ProteinModelPortaliQ2HQL9
SMRiQ2HQL9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoai4R79.1b; 4R79.1b; WBGene00003525
GeneIDi181796
UCSCi4R79.1a c. elegans

Organism-specific databases

CTDi181796
WormBasei4R79.1b ; CE39659 ; WBGene00003525 ; nas-6

Phylogenomic databases

eggNOGiKOG3714 Eukaryota
ENOG410ZPX7 LUCA
GeneTreeiENSGT00760000119227
HOGENOMiHOG000200198
OrthoDBiEOG091G009U

Gene expression databases

BgeeiWBGene00003525 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

Gene3Di3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR001506 Peptidase_M12A
IPR003582 ShKT_dom
PfamiView protein in Pfam
PF01400 Astacin, 1 hit
PF01549 ShK, 1 hit
PRINTSiPR00480 ASTACIN
SMARTiView protein in SMART
SM00254 ShKT, 1 hit
PROSITEiView protein in PROSITE
PS51670 SHKT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ2HQL9_CAEEL
AccessioniPrimary (citable) accession number: Q2HQL9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 21, 2006
Last sequence update: March 21, 2006
Last modified: October 10, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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