UniProtKB - Q2G1F1 (Q2G1F1_STAA8)
Protein
Lysostaphin
Gene
SAOUHSC_00174
Organism
Staphylococcus aureus (strain NCTC 8325 / PS 47)
Status
Functioni
Catalytic activityi
- Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans.ARBA annotation EC:3.4.24.75
Cofactori
Zn2+ARBA annotation
GO - Molecular functioni
- metalloendopeptidase activity Source: GO_Central
Keywordsi
Molecular function | Hydrolase, MetalloproteaseARBA annotation, Protease |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:SAOUHSC_00174Imported |
Organismi | Staphylococcus aureus (strain NCTC 8325 / PS 47)Imported |
Taxonomic identifieri | 93061 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › |
Proteomesi |
|
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 7 – 25 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 75 – 166 | Peptidase_M23InterPro annotationAdd BLAST | 92 |
Sequence similaritiesi
Belongs to the peptidase M23B family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | COG0739, Bacteria |
HOGENOMi | CLU_121943_0_0_9 |
OMAi | NGDNRHY |
Family and domain databases
Gene3Di | 2.70.70.10, 1 hit |
InterProi | View protein in InterPro IPR011055, Dup_hybrid_motif IPR016047, Peptidase_M23 |
Pfami | View protein in Pfam PF01551, Peptidase_M23, 1 hit |
SUPFAMi | SSF51261, SSF51261, 1 hit |
i Sequence
Sequence statusi: Complete.
Q2G1F1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTKRPKRILA TIIIFLSLLF TIIYIDDIQK WFNQYTDKLT QNHKGQGHSK
60 70 80 90 100
WEDFFRGSRI TETFGKYQHS PFDGKHYGID FALPKGTPIK APTNGKVTRI
110 120 130 140 150
FNNELGGKVL QIAEDNGEYH QWYLHLDKYN VKVGDRVKAG DIIAYSGNTG
160 170 180 190
IQTTGAHLHF QRMKGGVGNA YAEDPKPFID QLPDGERSLY DL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000253 Genomic DNA Translation: ABD29352.1 |
RefSeqi | WP_000166917.1, NZ_LS483365.1 YP_498771.1, NC_007795.1 |
Genome annotation databases
EnsemblBacteriai | ABD29352; ABD29352; SAOUHSC_00174 |
GeneIDi | 3919488 |
KEGGi | sao:SAOUHSC_00174 |
PATRICi | fig|93061.5.peg.162 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000253 Genomic DNA Translation: ABD29352.1 |
RefSeqi | WP_000166917.1, NZ_LS483365.1 YP_498771.1, NC_007795.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5KQB | NMR | - | A | 49-192 | [»] | |
5KQC | NMR | - | A | 49-192 | [»] | |
BMRBi | Q2G1F1 | |||||
SMRi | Q2G1F1 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 1280.SAXN108_0188 |
Genome annotation databases
EnsemblBacteriai | ABD29352; ABD29352; SAOUHSC_00174 |
GeneIDi | 3919488 |
KEGGi | sao:SAOUHSC_00174 |
PATRICi | fig|93061.5.peg.162 |
Phylogenomic databases
eggNOGi | COG0739, Bacteria |
HOGENOMi | CLU_121943_0_0_9 |
OMAi | NGDNRHY |
Family and domain databases
Gene3Di | 2.70.70.10, 1 hit |
InterProi | View protein in InterPro IPR011055, Dup_hybrid_motif IPR016047, Peptidase_M23 |
Pfami | View protein in Pfam PF01551, Peptidase_M23, 1 hit |
SUPFAMi | SSF51261, SSF51261, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q2G1F1_STAA8 | |
Accessioni | Q2G1F1Primary (citable) accession number: Q2G1F1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 21, 2006 |
Last sequence update: | March 21, 2006 | |
Last modified: | April 7, 2021 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |