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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Staphylococcus aureus (strain NCTC 8325)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciSAUR93061:G1G5Y-2375-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Ordered Locus Names:SAOUHSC_02512
OrganismiStaphylococcus aureus (strain NCTC 8325)
Taxonomic identifieri93061 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000008816 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000521491 – 22050S ribosomal protein L3Add BLAST220

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi93061.SAOUHSC_02512

Structurei

Secondary structure

1220
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Beta strandi9 – 16Combined sources8
Beta strandi22 – 28Combined sources7
Beta strandi34 – 39Combined sources6
Helixi41 – 44Combined sources4
Beta strandi48 – 52Combined sources5
Beta strandi57 – 60Combined sources4
Helixi71 – 78Combined sources8
Turni79 – 81Combined sources3
Beta strandi88 – 94Combined sources7
Beta strandi96 – 98Combined sources3
Turni100 – 102Combined sources3
Helixi107 – 109Combined sources3
Beta strandi115 – 119Combined sources5
Beta strandi124 – 128Combined sources5
Helixi130 – 134Combined sources5
Beta strandi141 – 144Combined sources4
Beta strandi148 – 150Combined sources3
Beta strandi157 – 160Combined sources4
Beta strandi171 – 174Combined sources4
Beta strandi179 – 185Combined sources7
Turni190 – 193Combined sources4
Beta strandi197 – 199Combined sources3
Beta strandi205 – 207Combined sources3
Beta strandi210 – 213Combined sources4

3D structure databases

ProteinModelPortaliQ2FW06
SMRiQ2FW06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL3 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EEE Bacteria
COG0087 LUCA
HOGENOMiHOG000100368
KOiK02906
OMAiKGMRMAG

Family and domain databases

HAMAPiMF_01325_B Ribosomal_L3_B, 1 hit
InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019927 Ribosomal_L3_bac/org-type
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11229 PTHR11229, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03625 L3_bact, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

Sequencei

Sequence statusi: Complete.

Q2FW06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKGILGRKI GMTQVFGENG ELIPVTVVEA KENVVLQKKT VEVDGYNAIQ
60 70 80 90 100
VGFEDKKAYK KDAKSNKYAN KPAEGHAKKA DAAPKRFIRE FRNVDVDAYE
110 120 130 140 150
VGQEVSVDTF VAGDVIDVTG VSKGKGFQGA IKRHGQSRGP MSHGSHFHRA
160 170 180 190 200
PGSVGMASDA SRVFKGQKMP GRMGGNTVTV QNLEVVQVDT ENKVILVKGN
210 220
VPGPKKGLVE IRTSIKKGNK
Length:220
Mass (Da):23,718
Last modified:March 21, 2006 - v1
Checksum:i27BAE1308C8F0675
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000253 Genomic DNA Translation: ABD31530.1
RefSeqiWP_000160212.1, NC_007795.1
YP_500979.1, NC_007795.1

Genome annotation databases

EnsemblBacteriaiABD31530; ABD31530; SAOUHSC_02512
GeneIDi3920888
KEGGisao:SAOUHSC_02512
PATRICifig|93061.5.peg.2267

Similar proteinsi

Entry informationi

Entry nameiRL3_STAA8
AccessioniPrimary (citable) accession number: Q2FW06
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 21, 2006
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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