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Entry version 86 (02 Dec 2020)
Sequence version 2 (11 Sep 2007)
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Protein

Mediator of RNA polymerase II transcription subunit 7

Gene

MED7

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SSC-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mediator of RNA polymerase II transcription subunit 7
Alternative name(s):
Cofactor required for Sp1 transcriptional activation subunit 9
Short name:
CRSP complex subunit 9
Mediator complex subunit 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MED7
Synonyms:CRSP9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced
  • UP000008227 Componenti: Chromosome 16

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:90123, MED7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003031801 – 233Mediator of RNA polymerase II transcription subunit 7Add BLAST233

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki185Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki185Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei194PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q2F7Z4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000017058, Expressed in testis and 37 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q2F7Z4, baseline

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q2F7Z4, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000018072

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q2F7Z4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Mediator complex subunit 7 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0570, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154444

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_065214_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q2F7Z4

Identification of Orthologs from Complete Genome Data

More...
OMAi
MCSIIDE

Database of Orthologous Groups

More...
OrthoDBi
1356482at2759

TreeFam database of animal gene trees

More...
TreeFami
TF314411

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037212, Med7/Med21-like
IPR009244, Mediatior_Med7

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05983, Med7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF140718, SSF140718, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q2F7Z4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEPQQVSAL PPPPMQYIKE YTDENIQEGL APKPPPPIKD SYMMFGNQFQ
60 70 80 90 100
CDDLIIRPLE SQGIERLHPM QFDHKKELRK LNMSILINFL DLLDILIRSP
110 120 130 140 150
GSIKREEKLE DLKLLFVHVH HLINEYRPHQ ARETLRVMME VQKRQRLETA
160 170 180 190 200
ERFQKHLERV IEMIQNCLAS LPDDLPHSEA GMRVKAEPMD ADDSNNCTGQ
210 220 230
SDQQRENSGH RRDQIIEKDA ALCVLIDEMN ERP
Length:233
Mass (Da):27,165
Last modified:September 11, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i425106E8360B84E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti179E → V in ABB02676 (PubMed:16484800).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ200861 Genomic DNA Translation: ABB02674.1
DQ200863 mRNA Translation: ABB02676.1

NCBI Reference Sequences

More...
RefSeqi
NP_001038080.1, NM_001044615.1
XP_005672641.1, XM_005672584.2
XP_005672642.1, XM_005672585.2
XP_005672643.1, XM_005672586.2
XP_005672644.1, XM_005672587.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000018572; ENSSSCP00000018072; ENSSSCG00000017058
ENSSSCT00000068622; ENSSSCP00000067996; ENSSSCG00000017058
ENSSSCT00000068927; ENSSSCP00000074390; ENSSSCG00000017058
ENSSSCT00000072169; ENSSSCP00000069715; ENSSSCG00000017058
ENSSSCT00000078443; ENSSSCP00000060392; ENSSSCG00000017058
ENSSSCT00000087107; ENSSSCP00000070953; ENSSSCG00000017058
ENSSSCT00005058163; ENSSSCP00005035907; ENSSSCG00005036433
ENSSSCT00005058186; ENSSSCP00005035922; ENSSSCG00005036433
ENSSSCT00005058191; ENSSSCP00005035924; ENSSSCG00005036433
ENSSSCT00005058195; ENSSSCP00005035927; ENSSSCG00005036433
ENSSSCT00005058201; ENSSSCP00005035929; ENSSSCG00005036433
ENSSSCT00005058204; ENSSSCP00005035931; ENSSSCG00005036433
ENSSSCT00015007794; ENSSSCP00015003154; ENSSSCG00015005855
ENSSSCT00015007824; ENSSSCP00015003170; ENSSSCG00015005855
ENSSSCT00015007841; ENSSSCP00015003173; ENSSSCG00015005855
ENSSSCT00015007847; ENSSSCP00015003175; ENSSSCG00015005855
ENSSSCT00015007851; ENSSSCP00015003177; ENSSSCG00015005855
ENSSSCT00025038954; ENSSSCP00025016480; ENSSSCG00025028703
ENSSSCT00025039051; ENSSSCP00025016524; ENSSSCG00025028703
ENSSSCT00025039107; ENSSSCP00025016550; ENSSSCG00025028703
ENSSSCT00025039130; ENSSSCP00025016561; ENSSSCG00025028703
ENSSSCT00025039175; ENSSSCP00025016582; ENSSSCG00025028703
ENSSSCT00025039190; ENSSSCP00025016589; ENSSSCG00025028703
ENSSSCT00030020331; ENSSSCP00030009062; ENSSSCG00030014759
ENSSSCT00030020337; ENSSSCP00030009063; ENSSSCG00030014759
ENSSSCT00030020345; ENSSSCP00030009067; ENSSSCG00030014759
ENSSSCT00030020355; ENSSSCP00030009071; ENSSSCG00030014759
ENSSSCT00030020364; ENSSSCP00030009076; ENSSSCG00030014759
ENSSSCT00030020376; ENSSSCP00030009083; ENSSSCG00030014759
ENSSSCT00035066123; ENSSSCP00035026823; ENSSSCG00035049608
ENSSSCT00035066129; ENSSSCP00035026826; ENSSSCG00035049608
ENSSSCT00035066131; ENSSSCP00035026827; ENSSSCG00035049608
ENSSSCT00035066134; ENSSSCP00035026829; ENSSSCG00035049608
ENSSSCT00035066136; ENSSSCP00035026830; ENSSSCG00035049608
ENSSSCT00040063580; ENSSSCP00040026848; ENSSSCG00040047209
ENSSSCT00040063632; ENSSSCP00040026874; ENSSSCG00040047209
ENSSSCT00040063657; ENSSSCP00040026883; ENSSSCG00040047209
ENSSSCT00040063760; ENSSSCP00040026925; ENSSSCG00040047209
ENSSSCT00040063793; ENSSSCP00040026941; ENSSSCG00040047209
ENSSSCT00045013336; ENSSSCP00045009196; ENSSSCG00045007956
ENSSSCT00045013361; ENSSSCP00045009214; ENSSSCG00045007956
ENSSSCT00045013376; ENSSSCP00045009225; ENSSSCG00045007956
ENSSSCT00045013394; ENSSSCP00045009240; ENSSSCG00045007956
ENSSSCT00045013407; ENSSSCP00045009250; ENSSSCG00045007956
ENSSSCT00050041688; ENSSSCP00050017224; ENSSSCG00050031016
ENSSSCT00050041694; ENSSSCP00050017226; ENSSSCG00050031016
ENSSSCT00050041699; ENSSSCP00050017228; ENSSSCG00050031016
ENSSSCT00050041704; ENSSSCP00050017232; ENSSSCG00050031016
ENSSSCT00050041707; ENSSSCP00050017234; ENSSSCG00050031016
ENSSSCT00050041713; ENSSSCP00050017240; ENSSSCG00050031016
ENSSSCT00055013659; ENSSSCP00055010755; ENSSSCG00055007049
ENSSSCT00055013696; ENSSSCP00055010783; ENSSSCG00055007049
ENSSSCT00055013718; ENSSSCP00055010798; ENSSSCG00055007049
ENSSSCT00055013737; ENSSSCP00055010814; ENSSSCG00055007049
ENSSSCT00055013748; ENSSSCP00055010824; ENSSSCG00055007049
ENSSSCT00055013757; ENSSSCP00055010833; ENSSSCG00055007049
ENSSSCT00060027098; ENSSSCP00060011546; ENSSSCG00060020044
ENSSSCT00060027099; ENSSSCP00060011547; ENSSSCG00060020044
ENSSSCT00060027100; ENSSSCP00060011548; ENSSSCG00060020044
ENSSSCT00060027104; ENSSSCP00060011550; ENSSSCG00060020044
ENSSSCT00060027107; ENSSSCP00060011551; ENSSSCG00060020044
ENSSSCT00060027109; ENSSSCP00060011552; ENSSSCG00060020044
ENSSSCT00065068071; ENSSSCP00065029638; ENSSSCG00065049702
ENSSSCT00065068076; ENSSSCP00065029642; ENSSSCG00065049702
ENSSSCT00065068078; ENSSSCP00065029644; ENSSSCG00065049702
ENSSSCT00065068086; ENSSSCP00065029647; ENSSSCG00065049702
ENSSSCT00065068090; ENSSSCP00065029648; ENSSSCG00065049702
ENSSSCT00065068091; ENSSSCP00065029649; ENSSSCG00065049702

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
733689

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:733689

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ200861 Genomic DNA Translation: ABB02674.1
DQ200863 mRNA Translation: ABB02676.1
RefSeqiNP_001038080.1, NM_001044615.1
XP_005672641.1, XM_005672584.2
XP_005672642.1, XM_005672585.2
XP_005672643.1, XM_005672586.2
XP_005672644.1, XM_005672587.2

3D structure databases

SMRiQ2F7Z4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000018072

Proteomic databases

PaxDbiQ2F7Z4

Genome annotation databases

EnsembliENSSSCT00000018572; ENSSSCP00000018072; ENSSSCG00000017058
ENSSSCT00000068622; ENSSSCP00000067996; ENSSSCG00000017058
ENSSSCT00000068927; ENSSSCP00000074390; ENSSSCG00000017058
ENSSSCT00000072169; ENSSSCP00000069715; ENSSSCG00000017058
ENSSSCT00000078443; ENSSSCP00000060392; ENSSSCG00000017058
ENSSSCT00000087107; ENSSSCP00000070953; ENSSSCG00000017058
ENSSSCT00005058163; ENSSSCP00005035907; ENSSSCG00005036433
ENSSSCT00005058186; ENSSSCP00005035922; ENSSSCG00005036433
ENSSSCT00005058191; ENSSSCP00005035924; ENSSSCG00005036433
ENSSSCT00005058195; ENSSSCP00005035927; ENSSSCG00005036433
ENSSSCT00005058201; ENSSSCP00005035929; ENSSSCG00005036433
ENSSSCT00005058204; ENSSSCP00005035931; ENSSSCG00005036433
ENSSSCT00015007794; ENSSSCP00015003154; ENSSSCG00015005855
ENSSSCT00015007824; ENSSSCP00015003170; ENSSSCG00015005855
ENSSSCT00015007841; ENSSSCP00015003173; ENSSSCG00015005855
ENSSSCT00015007847; ENSSSCP00015003175; ENSSSCG00015005855
ENSSSCT00015007851; ENSSSCP00015003177; ENSSSCG00015005855
ENSSSCT00025038954; ENSSSCP00025016480; ENSSSCG00025028703
ENSSSCT00025039051; ENSSSCP00025016524; ENSSSCG00025028703
ENSSSCT00025039107; ENSSSCP00025016550; ENSSSCG00025028703
ENSSSCT00025039130; ENSSSCP00025016561; ENSSSCG00025028703
ENSSSCT00025039175; ENSSSCP00025016582; ENSSSCG00025028703
ENSSSCT00025039190; ENSSSCP00025016589; ENSSSCG00025028703
ENSSSCT00030020331; ENSSSCP00030009062; ENSSSCG00030014759
ENSSSCT00030020337; ENSSSCP00030009063; ENSSSCG00030014759
ENSSSCT00030020345; ENSSSCP00030009067; ENSSSCG00030014759
ENSSSCT00030020355; ENSSSCP00030009071; ENSSSCG00030014759
ENSSSCT00030020364; ENSSSCP00030009076; ENSSSCG00030014759
ENSSSCT00030020376; ENSSSCP00030009083; ENSSSCG00030014759
ENSSSCT00035066123; ENSSSCP00035026823; ENSSSCG00035049608
ENSSSCT00035066129; ENSSSCP00035026826; ENSSSCG00035049608
ENSSSCT00035066131; ENSSSCP00035026827; ENSSSCG00035049608
ENSSSCT00035066134; ENSSSCP00035026829; ENSSSCG00035049608
ENSSSCT00035066136; ENSSSCP00035026830; ENSSSCG00035049608
ENSSSCT00040063580; ENSSSCP00040026848; ENSSSCG00040047209
ENSSSCT00040063632; ENSSSCP00040026874; ENSSSCG00040047209
ENSSSCT00040063657; ENSSSCP00040026883; ENSSSCG00040047209
ENSSSCT00040063760; ENSSSCP00040026925; ENSSSCG00040047209
ENSSSCT00040063793; ENSSSCP00040026941; ENSSSCG00040047209
ENSSSCT00045013336; ENSSSCP00045009196; ENSSSCG00045007956
ENSSSCT00045013361; ENSSSCP00045009214; ENSSSCG00045007956
ENSSSCT00045013376; ENSSSCP00045009225; ENSSSCG00045007956
ENSSSCT00045013394; ENSSSCP00045009240; ENSSSCG00045007956
ENSSSCT00045013407; ENSSSCP00045009250; ENSSSCG00045007956
ENSSSCT00050041688; ENSSSCP00050017224; ENSSSCG00050031016
ENSSSCT00050041694; ENSSSCP00050017226; ENSSSCG00050031016
ENSSSCT00050041699; ENSSSCP00050017228; ENSSSCG00050031016
ENSSSCT00050041704; ENSSSCP00050017232; ENSSSCG00050031016
ENSSSCT00050041707; ENSSSCP00050017234; ENSSSCG00050031016
ENSSSCT00050041713; ENSSSCP00050017240; ENSSSCG00050031016
ENSSSCT00055013659; ENSSSCP00055010755; ENSSSCG00055007049
ENSSSCT00055013696; ENSSSCP00055010783; ENSSSCG00055007049
ENSSSCT00055013718; ENSSSCP00055010798; ENSSSCG00055007049
ENSSSCT00055013737; ENSSSCP00055010814; ENSSSCG00055007049
ENSSSCT00055013748; ENSSSCP00055010824; ENSSSCG00055007049
ENSSSCT00055013757; ENSSSCP00055010833; ENSSSCG00055007049
ENSSSCT00060027098; ENSSSCP00060011546; ENSSSCG00060020044
ENSSSCT00060027099; ENSSSCP00060011547; ENSSSCG00060020044
ENSSSCT00060027100; ENSSSCP00060011548; ENSSSCG00060020044
ENSSSCT00060027104; ENSSSCP00060011550; ENSSSCG00060020044
ENSSSCT00060027107; ENSSSCP00060011551; ENSSSCG00060020044
ENSSSCT00060027109; ENSSSCP00060011552; ENSSSCG00060020044
ENSSSCT00065068071; ENSSSCP00065029638; ENSSSCG00065049702
ENSSSCT00065068076; ENSSSCP00065029642; ENSSSCG00065049702
ENSSSCT00065068078; ENSSSCP00065029644; ENSSSCG00065049702
ENSSSCT00065068086; ENSSSCP00065029647; ENSSSCG00065049702
ENSSSCT00065068090; ENSSSCP00065029648; ENSSSCG00065049702
ENSSSCT00065068091; ENSSSCP00065029649; ENSSSCG00065049702
GeneIDi733689
KEGGissc:733689

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
9443
VGNCiVGNC:90123, MED7

Phylogenomic databases

eggNOGiKOG0570, Eukaryota
GeneTreeiENSGT00940000154444
HOGENOMiCLU_065214_2_0_1
InParanoidiQ2F7Z4
OMAiMCSIIDE
OrthoDBi1356482at2759
TreeFamiTF314411

Enzyme and pathway databases

ReactomeiR-SSC-212436, Generic Transcription Pathway

Gene expression databases

BgeeiENSSSCG00000017058, Expressed in testis and 37 other tissues
ExpressionAtlasiQ2F7Z4, baseline
GenevisibleiQ2F7Z4, SS

Family and domain databases

InterProiView protein in InterPro
IPR037212, Med7/Med21-like
IPR009244, Mediatior_Med7
PfamiView protein in Pfam
PF05983, Med7, 1 hit
SUPFAMiSSF140718, SSF140718, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMED7_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q2F7Z4
Secondary accession number(s): Q2F7Z6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 2, 2020
This is version 86 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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