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Entry version 91 (12 Aug 2020)
Sequence version 2 (14 Oct 2008)
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Protein
Submitted name:

Uncharacterized protein, isoform A

Gene

Dpse\GA19765

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dpse\GA19765Imported
ORF Names:Dpse_GA19765Imported, GA19765Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri46245 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0079761, Dpse\GA19765

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0079761, Expressed in female reproductive system and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7237.FBpp0280062

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q29MQ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini57 – 236RHDInterPro annotationAdd BLAST180

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 63DisorderedSequence analysisAdd BLAST63
Regioni365 – 473DisorderedSequence analysisAdd BLAST109
Regioni500 – 529DisorderedSequence analysisAdd BLAST30
Regioni600 – 664DisorderedSequence analysisAdd BLAST65

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi20 – 58PolarSequence analysisAdd BLAST39
Compositional biasi365 – 397PolarSequence analysisAdd BLAST33
Compositional biasi421 – 473PolarSequence analysisAdd BLAST53

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQS6, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004343_4_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q29MQ9

KEGG Orthology (KO)

More...
KOi
K09254

Identification of Orthologs from Complete Genome Data

More...
OMAi
NNMNCWN

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01177, IPT_NFkappaB, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
2.60.40.340, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011363, Dif
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR033926, IPT_NFkappaB
IPR000451, NFkB/Dor
IPR008967, p53-like_TF_DNA-bd
IPR030492, RHD_CS
IPR032397, RHD_dimer
IPR011539, RHD_DNA_bind_dom
IPR037059, RHD_DNA_bind_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24169, PTHR24169, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16179, RHD_dimer, 1 hit
PF00554, RHD_DNA_bind, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF001716, Dorsal, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00057, NFKBTNSCPFCT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00429, IPT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49417, SSF49417, 1 hit
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01204, REL_1, 1 hit
PS50254, REL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q29MQ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFPNQNNVAA AGPGGPAVDG QQSLNYNGLP QQQQQQQQQQ QQQQQQQQLS
60 70 80 90 100
QSTKNVRKKP YVKITEQPAG KALRFRYECE GRSAGSIPGV NSTPENKTYP
110 120 130 140 150
TIEIVGYKGR AVVVVSCVTK DTPYRPHPHN LVGKEGCKKG VCTLEINSET
160 170 180 190 200
MRAVFSNLGI QCVKKKDIEA ALKAREEIRV DPFKTGFSHR FQPSSIDLNS
210 220 230 240 250
VRLCFQVFME SEQKGRFTSP LPPVVSEPIF DKKAMSDLVI CRLCSCSATV
260 270 280 290 300
LGNTQIILLC EKVAKEDISV RFFEEKNGQS VWEAFGDFQH TDVHKQTAIT
310 320 330 340 350
FKTPRYHTLD ITEPAKVFIQ LRRPSDGVTS ESLPFEYVPL DSDPAHLRRK
360 370 380 390 400
RQKTGGDPMH LLLQQQQKQQ LQNDHQDGRQ NNMNCWNAQN IPPIKTEPRD
410 420 430 440 450
TSPQPFGLYR APPELTPSPQ PLSPSSNYNH NSTPSPYNLA ATPTNGQQQM
460 470 480 490 500
MSPNHPQQQQ QQHQQQPQQQ QQYGATELGN SYNPFTQQVL AQQQQQQQQH
510 520 530 540 550
QQQQQQQQQQ QQQAMQFHGN PFGNTGSSHW ETKFSAASVA AAAAAAAAAT
560 570 580 590 600
PATNTNNNSN NLSNLNNPFT MHNLLTSGGG GAGPGGSLQW NLTTNHLHNQ
610 620 630 640 650
HTLHQQQQQQ LQQHQQQHAP SMHQYDNGSN NNPNNNNTNN NSNNTNNNNT
660 670 680 690 700
NASNQPDNGP TISNLLSFDS EQLVRINSED QQILRLNSED LQISNLSIST
Length:700
Mass (Da):78,129
Last modified:October 14, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB7C67C7C8E94E24F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH379060 Genomic DNA Translation: EAL33634.2

NCBI Reference Sequences

More...
RefSeqi
XP_001356570.2, XM_001356534.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0281624; FBpp0280062; FBgn0079761

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4817309

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dpo:Dpse_GA19765

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379060 Genomic DNA Translation: EAL33634.2
RefSeqiXP_001356570.2, XM_001356534.3

3D structure databases

SMRiQ29MQ9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7237.FBpp0280062

Genome annotation databases

EnsemblMetazoaiFBtr0281624; FBpp0280062; FBgn0079761
GeneIDi4817309
KEGGidpo:Dpse_GA19765

Organism-specific databases

FlyBaseiFBgn0079761, Dpse\GA19765

Phylogenomic databases

eggNOGiENOG502QQS6, Eukaryota
HOGENOMiCLU_004343_4_0_1
InParanoidiQ29MQ9
KOiK09254
OMAiNNMNCWN

Gene expression databases

BgeeiFBgn0079761, Expressed in female reproductive system and 4 other tissues

Family and domain databases

CDDicd01177, IPT_NFkappaB, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR011363, Dif
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR033926, IPT_NFkappaB
IPR000451, NFkB/Dor
IPR008967, p53-like_TF_DNA-bd
IPR030492, RHD_CS
IPR032397, RHD_dimer
IPR011539, RHD_DNA_bind_dom
IPR037059, RHD_DNA_bind_dom_sf
PANTHERiPTHR24169, PTHR24169, 1 hit
PfamiView protein in Pfam
PF16179, RHD_dimer, 1 hit
PF00554, RHD_DNA_bind, 1 hit
PIRSFiPIRSF001716, Dorsal, 2 hits
PRINTSiPR00057, NFKBTNSCPFCT
SMARTiView protein in SMART
SM00429, IPT, 1 hit
SUPFAMiSSF49417, SSF49417, 1 hit
SSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS01204, REL_1, 1 hit
PS50254, REL_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ29MQ9_DROPS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q29MQ9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: October 14, 2008
Last modified: August 12, 2020
This is version 91 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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