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Entry version 92 (12 Aug 2020)
Sequence version 3 (20 Jan 2016)
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Protein
Submitted name:

Uncharacterized protein, isoform A

Gene

Dpse\GA10815

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dpse\GA10815Imported
ORF Names:Dpse_GA10815Imported, GA10815Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri46245 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0070871, Dpse\GA10815

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0070871, Expressed in head and 3 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7237.FBpp0285490

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q29FM6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini432 – 614RHDInterPro annotationAdd BLAST183

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 34DisorderedSequence analysisAdd BLAST34
Regioni61 – 137DisorderedSequence analysisAdd BLAST77
Regioni177 – 211DisorderedSequence analysisAdd BLAST35
Regioni238 – 258DisorderedSequence analysisAdd BLAST21
Regioni758 – 792DisorderedSequence analysisAdd BLAST35
Regioni853 – 881DisorderedSequence analysisAdd BLAST29
Regioni1024 – 1066DisorderedSequence analysisAdd BLAST43
Regioni1214 – 1251DisorderedSequence analysisAdd BLAST38
Regioni1286 – 1334DisorderedSequence analysisAdd BLAST49

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili348 – 368Sequence analysisAdd BLAST21
Coiled coili932 – 961Sequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 34PolarSequence analysisAdd BLAST24
Compositional biasi106 – 128PolarSequence analysisAdd BLAST23
Compositional biasi758 – 786PolarSequence analysisAdd BLAST29
Compositional biasi1294 – 1332BasicSequence analysisAdd BLAST39

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSVE, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_251360_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q29FM6

KEGG Orthology (KO)

More...
KOi
K17335

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
2.60.40.340, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR008366, NFAT
IPR008967, p53-like_TF_DNA-bd
IPR032397, RHD_dimer
IPR011539, RHD_DNA_bind_dom
IPR037059, RHD_DNA_bind_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12533, PTHR12533, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16179, RHD_dimer, 1 hit
PF00554, RHD_DNA_bind, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00429, IPT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49417, SSF49417, 1 hit
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50254, REL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q29FM6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLKFTKTSG AGNAGPGSVA GSSSSSMQTT TSYAARGTGM RMTMSTNSTM
60 70 80 90 100
SARIHRKGFR IPSKRQPGKG LPGKLHTITR AGPGKIVPGK RIPQRPHLPP
110 120 130 140 150
CDNSNDSGLG FDQHTELRSS SGPGVADTGS SNGGGIGMGA VQRTNLLVNS
160 170 180 190 200
SLTNTVAAAA AAAAAAVASN TLQQHHQQQQ QQQQQQHQQQ QQQQQQHQQQ
210 220 230 240 250
QQQHQQQHLP QQHLIRAIPV SRSRHTKKML SAFLDDLDLT NSNSNSEGST
260 270 280 290 300
ASTSLSCSAT PISEDTGFVN HSSSTPRNSS EPFGGVFQAT EAAVAAAVTA
310 320 330 340 350
FNVQNQQPLP QQQQQLLQQH FQYPEMVVQQ QQQQHHQRNL PRSGDKHIKR
360 370 380 390 400
KKLEYNQLEL DNDDACSEDE FIRKIANAAI ASSSEEAVLV APVAPVAPAR
410 420 430 440 450
PPPAMTSVLP RNGHETKFIS ARTVTRVANK RQPATPLNSV ASSNDGHVQL
460 470 480 490 500
EIVSQPEQQH RARYQTEGSR GAVKDRSGNG FPIVRLTGYD KGAVLQVFIG
510 520 530 540 550
TDIGRVAPHM FYQACKVAGK NSTQCNEKKV DGTMVIEIDF KPETDMTITC
560 570 580 590 600
DCVGILKERN VDVEHRFPEH LAQKNKKKST RCRMVFRTQL TREDGTTETL
610 620 630 640 650
QVCSNPIICT QPPGVPEICK KSLNSCPVDG GLELFIIGKN FLKDTHVVFQ
660 670 680 690 700
ETYDSVNGDD PATEIAVRQQ LIGGTAALWE QSVMPDKEYL HQTHLICTVP
710 720 730 740 750
PYLHENVIKP VSVQVSIVSS GKKSEPHTFT YTPKGQFSTL AAASTLSSTI
760 770 780 790 800
HDQDVNHFMD TTASPSSSGS NWSANSQASG SGSGPASSGE GVVVETKHEI
810 820 830 840 850
DSGMMPPPIT TQIPMGVVRR SSLPSATPMI TDQQLVHLNA VAVASAEALK
860 870 880 890 900
SELIDESSTN SPLTAEPTPD SPNGMQYHHQ THFARKSSLD TIMFDQSNSL
910 920 930 940 950
PGFPVTAVDI DSAAVAVAVE LAVKNEIVKH VVQQHQQQQQ QQQQQQQQQQ
960 970 980 990 1000
QQQQQQQQQQ QPQQQQQATA AAAASVHKFI DELTKSTSVV SSNGTTESAL
1010 1020 1030 1040 1050
FTSAAVIDHA LTDILQSKVG VLSHGSHQTG APTNGVLERS LSLGSTNSSS
1060 1070 1080 1090 1100
SLSGNESSPN SSPLTQDIIL NSEPAAALAG APILAPSPVD VGASLSTDII
1110 1120 1130 1140 1150
MNPAVSPSTI LCSANGAATA VVPNILAPHQ VTMANSILND IAMQPEPTQQ
1160 1170 1180 1190 1200
DAAVAALALS NIMMSPPTSA GGVVDALPPT PAALQPEVTA TATSTAVSNM
1210 1220 1230 1240 1250
IIKAAADFIT TQEQEQHHYH HQHTRTHTHS HTHSHTRSPQ SGVAVTTNPV
1260 1270 1280 1290 1300
DAGEDPLVNL LLSHATPPET AVAAAAAVAA EAASFQSLSG HGHSHGHSHS
1310 1320 1330 1340 1350
HSHSHSHSHS HSHSHSHGHG HGHVHGHGHS HGHAHLPVVA ATPQESLIVA
1360 1370 1380 1390 1400
LASENALQKS VATAAVTTNG AVMTQQASAP TTAGSILPAA VGAVAAAAAV
1410 1420 1430
AVQPPIPQEL TTMSDQDLIS YINPSTFDQL
Length:1,430
Mass (Da):151,770
Last modified:January 20, 2016 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF766F6BB56B9AD18
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH379066 Genomic DNA Translation: EAL31374.3

NCBI Reference Sequences

More...
RefSeqi
XP_001354321.3, XM_001354285.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0287052; FBpp0285490; FBgn0070871

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dpo:Dpse_GA10815

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH379066 Genomic DNA Translation: EAL31374.3
RefSeqiXP_001354321.3, XM_001354285.3

3D structure databases

SMRiQ29FM6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7237.FBpp0285490

Genome annotation databases

EnsemblMetazoaiFBtr0287052; FBpp0285490; FBgn0070871
KEGGidpo:Dpse_GA10815

Organism-specific databases

FlyBaseiFBgn0070871, Dpse\GA10815

Phylogenomic databases

eggNOGiENOG502QSVE, Eukaryota
HOGENOMiCLU_251360_0_0_1
InParanoidiQ29FM6
KOiK17335

Gene expression databases

BgeeiFBgn0070871, Expressed in head and 3 other tissues

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR008366, NFAT
IPR008967, p53-like_TF_DNA-bd
IPR032397, RHD_dimer
IPR011539, RHD_DNA_bind_dom
IPR037059, RHD_DNA_bind_dom_sf
PANTHERiPTHR12533, PTHR12533, 2 hits
PfamiView protein in Pfam
PF16179, RHD_dimer, 1 hit
PF00554, RHD_DNA_bind, 1 hit
SMARTiView protein in SMART
SM00429, IPT, 1 hit
SUPFAMiSSF49417, SSF49417, 1 hit
SSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS50254, REL_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ29FM6_DROPS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q29FM6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: January 20, 2016
Last modified: August 12, 2020
This is version 92 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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