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UniProtKB - Q28C74 (LPPRC_XENTR)

Entry version 74 (29 Sep 2021)
Sequence version 1 (04 Apr 2006)
Previous versions | rss
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Protein

Leucine-rich PPR motif-containing protein, mitochondrial

Gene

lrpprc

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in RNA metabolism in both nuclei and mitochondria. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. May be involved in transcription regulation. Binds single-stranded DNA (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, RNA-binding
Biological processTranscription, Transcription regulation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leucine-rich PPR motif-containing protein, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lrpprc
ORF Names:TTpA007l07.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...Xenbasei		XB-GENE-1014657, lrpprc

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 42MitochondrionSequence analysisAdd BLAST42
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000033861843 – 1391Leucine-rich PPR motif-containing protein, mitochondrialAdd BLAST1349

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q28C74

PRoteomics IDEntifications database

More...PRIDEi		Q28C74

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		8364.ENSXETP00000060744

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati110 – 144PPR 1Add BLAST35
Repeati145 – 179PPR 2Add BLAST35
Repeati180 – 214PPR 3Add BLAST35
Repeati215 – 249PPR 4Add BLAST35
Repeati250 – 284PPR 5Add BLAST35
Repeati389 – 425PPR 6Add BLAST37
Repeati704 – 738PPR 7Add BLAST35
Repeati741 – 775PPR 8Add BLAST35
Repeati779 – 813PPR 9Add BLAST35
Repeati815 – 850PPR 10Add BLAST36
Repeati948 – 982PPR 11Add BLAST35
Repeati1028 – 1062PPR 12Add BLAST35
Repeati1063 – 1093PPR 13Add BLAST31
Repeati1100 – 1134PPR 14Add BLAST35
Repeati1310 – 1344PPR 15Add BLAST35

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1118 – 1387RNA-bindingBy similarityAdd BLAST270

Keywords - Domaini

Repeat, Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4318, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q28C74

Database of Orthologous Groups

More...OrthoDBi		1344243at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR033490, LRP130
IPR002885, Pentatricopeptide_repeat
IPR033443, PPR_long
IPR011990, TPR-like_helical_dom_sf

The PANTHER Classification System

More...PANTHERi		PTHR46669, PTHR46669, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01535, PPR, 3 hits
PF13812, PPR_3, 1 hit
PF17177, PPR_long, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00756, PPR, 4 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51375, PPR, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q28C74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSALLAGARF LLRPGLRALP APCVRLSPGQ GRYLNNTPGH FAIAAQQKGH 
        60         70         80         90        100
IHEEPVSAVR AKQAQQFDWA LNKLDSSVRR TGRITKTLLQ KIFHDVCRTG 
       110        120        130        140        150
YPSSNQALLL LRSCGSLLPE LQMSERTEMA HRIWEKLQEL GAVFDVSHYN 
       160        170        180        190        200
ALLKVYLQNE HKFSPTEYLA KMEAANVQPN RVTYQRLIAA YCNEGDIEGA 
       210        220        230        240        250
SKILGFMKNK DLPITEAVFN TLVTGHARAG DMENAKNILS VMRSAGIEPG 
       260        270        280        290        300
PETYVALLTA YAEKGDINNI KQTLENVEKN EGSLTDRDLM QVIWSLAKAG 
       310        320        330        340        350
YPQYVQDIVE RMRYDRGYIP DAMNLCLSLM TQGFEDVAFL VLKSFSAASH 
       360        370        380        390        400
DSPNGDSLHH GNFFLRHCVN LDKPANKVKQ FCDGLKEENL HSAPLQFALY 
       410        420        430        440        450
CSLDAKKADL ALELMKMMKQ EGMPVRPHYC WPLLISFQKE KNAEGTIKVI 
       460        470        480        490        500
KALSEIGVEL DVETYSNYVL SVFNDVKSAR AQLQEHGCTV DSSWFNLAEL 
       510        520        530        540        550
RHDAVSGNLE EVYSLLSSPS FPSVDLGHFR GSLITAFKRS NNVDLKAKIT 
       560        570        580        590        600
ELLYKDGRYC QAASGPNEAV GYFLYNLIDS MSDAEVQAKE EHLRQYFHQL 
       610        620        630        640        650
KNANIVISAN IYRGIRNLLD SSHVPELIKD VIVLVDSQET LTSSDIAKSA 
       660        670        680        690        700
ELKASTLEEE IETLKAENKP FGDVLKQLVM IHCSEENMQK ALEVKAKYEQ 
       710        720        730        740        750
ENLAIGTYAA LIQLCCRHDN PDEALNLKQE LNRKDSSAVL DTSKYLALVK 
       760        770        780        790        800
VFGKNGRIAD AINVLKEMKE KDVPLKETTT TSFFHILNAA ALRGDAETVD 
       810        820        830        840        850
KIHESIVTLG LAKPTSNLCS PLVSVHLEKG DLPAAMETLF TCSKKYNCMP 
       860        870        880        890        900
RLHDVLCRLV EKGDTDLLQK AMDHISQERG EMAMLYDLLF AFLHTGKYKE 
       910        920        930        940        950
ARKIIETPGL RARPGRLQWF AEKCIATNQM EALENLVDMT QKLFECDRDD 
       960        970        980        990       1000
MYYYLLKLCK ENDDWKKADS AWTKIQEENV IPRERTLRLL ADIFRRNGQE 
      1010       1020       1030       1040       1050
VPFDVPETWY KDAAESKVLA SSSAPSSPES SFQKRVQVLS KKNRAKDAYE 
      1060       1070       1080       1090       1100
AFMEGENNGT AMSASAYSSL IRSMLSEGML EEAKKVLNTA ENHIKGFTLN 
      1110       1120       1130       1140       1150
DAASSLLIIT QVRRDYLKDA LASLKAMLEG DKVPTQLAVT RLVQALALKG 
      1160       1170       1180       1190       1200
DLEGIEVVEN MMRNIGSSIR LSQMLFINNK MLAHLKRGKT EEAIELIEPL 
      1210       1220       1230       1240       1250
YTGTDSQVTS ISYVFRKAME EKMESALEKL SGMAERLANQ FAVYRPVTDL 
      1260       1270       1280       1290       1300
FLQYIQVGRK DDARFLLQRC GSIAEQTPVL VSFISRSAQI PGQAQLIKDL 
      1310       1320       1330       1340       1350
LELIPEFSER ETAYSYLMKC YATDKDATAA TALYEKMKSE SVSPDELFLK 
      1360       1370       1380       1390 
RLAVLLREAG EPVPFSEPPE SFKFYADKLK KDKADSYDDE H
Length:1,391
Mass (Da):156,250
Last modified:April 4, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i26245D6F7DEA4C9E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CR942422 mRNA Translation: CAJ83132.1

NCBI Reference Sequences

More...RefSeqi		NP_001039203.1, NM_001045738.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		734062

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		xtr:734062

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR942422 mRNA Translation: CAJ83132.1
RefSeqiNP_001039203.1, NM_001045738.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000060744

Proteomic databases

PaxDbiQ28C74
PRIDEiQ28C74

Genome annotation databases

GeneIDi734062
KEGGixtr:734062

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10128
XenbaseiXB-GENE-1014657, lrpprc

Phylogenomic databases

eggNOGiKOG4318, Eukaryota
InParanoidiQ28C74
OrthoDBi1344243at2759

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR033490, LRP130
IPR002885, Pentatricopeptide_repeat
IPR033443, PPR_long
IPR011990, TPR-like_helical_dom_sf
PANTHERiPTHR46669, PTHR46669, 2 hits
PfamiView protein in Pfam
PF01535, PPR, 3 hits
PF13812, PPR_3, 1 hit
PF17177, PPR_long, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
TIGRFAMsiTIGR00756, PPR, 4 hits
PROSITEiView protein in PROSITE
PS51375, PPR, 15 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLPPRC_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q28C74
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: April 4, 2006
Last modified: September 29, 2021
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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