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Protein

Neuropeptide Y receptor type 1

Gene

NPY1R

Organism
Ovis aries (Sheep)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Receptor for neuropeptide Y and peptide YY.

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Neuropeptide Y receptor type 1
Short name:
NPY1-R
Gene namesi
Name:NPY1R
OrganismiOvis aries (Sheep)
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei‹1 – 6Helical; Name=3Sequence analysis›6
Topological domaini7 – 24CytoplasmicSequence analysisAdd BLAST18
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 81ExtracellularSequence analysisAdd BLAST36
Transmembranei82 – 102HelicalSequence analysisAdd BLAST21
Topological domaini103 – ›116CytoplasmicSequence analysisAdd BLAST›14

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000069924‹1 – ›116Neuropeptide Y receptor type 1Add BLAST›116

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi56N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Lipoprotein, Palmitate

Structurei

3D structure databases

ProteinModelPortaliQ28602
SMRiQ28602
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG105676

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000351 NPY1_rcpt
PANTHERiPTHR43916:SF5 PTHR43916:SF5, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q28602-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LVLIAVERHQ LIINPRGWRP SNRHAYVGIA VIWVLAVASS LPFLIYQVLT
60 70 80 90 100
DEPFQNVTLD AFKDKYVCFD KFPSDSHRLS YTTLLLVLQY FGPLCFIFIC
110
YFKIYIRLKR RNNMMD
Length:116
Mass (Da):13,690
Last modified:November 1, 1996 - v1
Checksum:i4E398366FFAC6670
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei1161

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62122 mRNA Translation: AAB51032.1
UniGeneiOar.530

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62122 mRNA Translation: AAB51032.1
UniGeneiOar.530

3D structure databases

ProteinModelPortaliQ28602
SMRiQ28602
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG105676

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000351 NPY1_rcpt
PANTHERiPTHR43916:SF5 PTHR43916:SF5, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiNPY1R_SHEEP
AccessioniPrimary (citable) accession number: Q28602
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: December 20, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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