UniProtKB - Q27HX6 (Q27HX6_MANIN)
Protein
Profilin
Gene
N/A
Organism
Mangifera indica (Mango)
Status
Functioni
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.UniRule annotation
GO - Molecular functioni
- actin binding Source: UniProtKB-KW
Keywordsi
Molecular function | Actin-bindingUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: ProfilinUniRule annotation |
Organismi | Mangifera indica (Mango)Imported |
Taxonomic identifieri | 29780 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Sapindales › Anacardiaceae › Mangifera |
Subcellular locationi
Cytoskeleton
- cytoskeleton ARBA annotation
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotationARBA annotationInteractioni
Subunit structurei
Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.
UniRule annotationGO - Molecular functioni
- actin binding Source: UniProtKB-KW
Family & Domainsi
Sequence similaritiesi
Family and domain databases
CDDi | cd00148, PROF, 1 hit |
InterProi | View protein in InterPro IPR005455, PFN IPR036140, PFN_sf IPR027310, Profilin_CS |
PANTHERi | PTHR11604, PTHR11604, 1 hit |
Pfami | View protein in Pfam PF00235, Profilin, 1 hit |
PRINTSi | PR00392, PROFILIN PR01640, PROFILINPLNT |
SMARTi | View protein in SMART SM00392, PROF, 1 hit |
SUPFAMi | SSF55770, SSF55770, 1 hit |
PROSITEi | View protein in PROSITE PS00414, PROFILIN, 1 hit |
i Sequence
Sequence statusi: Complete.
Q27HX6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSWQAYVDDH LMCDIEGNHL AAAAILGQDG SVRAQSANFP QLKPEEVTGI
60 70 80 90 100
NNDFNEPGTL APTGLYLGGT KYMVIQGEPG AVIRGKKGPG GVTVKKTSMA
110 120 130
FVIGIYDEPM TPGQCNMIVE RLGDYLVEQG L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ400579 mRNA Translation: ABD62998.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ400579 mRNA Translation: ABD62998.1 |
3D structure databases
SMRi | Q27HX6 |
ModBasei | Search... |
Protein family/group databases
Allergomei | 2856, Man i 3 3783, Man i 3.02 |
Family and domain databases
CDDi | cd00148, PROF, 1 hit |
InterProi | View protein in InterPro IPR005455, PFN IPR036140, PFN_sf IPR027310, Profilin_CS |
PANTHERi | PTHR11604, PTHR11604, 1 hit |
Pfami | View protein in Pfam PF00235, Profilin, 1 hit |
PRINTSi | PR00392, PROFILIN PR01640, PROFILINPLNT |
SMARTi | View protein in SMART SM00392, PROF, 1 hit |
SUPFAMi | SSF55770, SSF55770, 1 hit |
PROSITEi | View protein in PROSITE PS00414, PROFILIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q27HX6_MANIN | |
Accessioni | Q27HX6Primary (citable) accession number: Q27HX6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 4, 2006 |
Last sequence update: | April 4, 2006 | |
Last modified: | October 7, 2020 | |
This is version 50 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |