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UniProtKB - Q27518 (C13A2_CAEEL)
Protein
Putative cytochrome P450 CYP13A2
Gene
cyp-13A2
Organism
Caenorhabditis elegans
Status
Functioni
Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Cofactori
hemeBy similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 460 | Iron (heme axial ligand)By similarity | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- iron ion binding Source: InterPro
- monooxygenase activity Source: UniProtKB-KW
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Keywordsi
Molecular function | Monooxygenase, Oxidoreductase |
Ligand | Heme, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:cyp-13A2 Synonyms:cyp13a2 ORF Names:T10B9.7 |
Organismi | Caenorhabditis elegans |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | T10B9.7 ; CE01659 ; WBGene00011676 ; cyp-13A2 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000052262 | 1 – 515 | Putative cytochrome P450 CYP13A2Add BLAST | 515 |
Proteomic databases
EPDi | Q27518 |
PaxDbi | Q27518 |
PeptideAtlasi | Q27518 |
Expressioni
Gene expression databases
Bgeei | WBGene00011676, Expressed in multi-cellular organism and 3 other tissues |
Interactioni
Protein-protein interaction databases
BioGRIDi | 53027, 1 interactor |
DIPi | DIP-25672N |
STRINGi | 6239.T10B9.7 |
Family & Domainsi
Sequence similaritiesi
Belongs to the cytochrome P450 family.Curated
Phylogenomic databases
eggNOGi | KOG0158, Eukaryota |
HOGENOMi | CLU_001570_5_2_1 |
InParanoidi | Q27518 |
OMAi | NIYVTHI |
OrthoDBi | 786853at2759 |
PhylomeDBi | Q27518 |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
i Sequence
Sequence statusi: Complete.
Q27518-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLGFVLAVT FSIFLGILTY YLWIWTYWMR KGVKGPRGRP FVGVLDVLLE
60 70 80 90 100
HETPGLIKLG EWTKKYGKVY GYTDGTQRTL VVADPAMVHE IFVKQFDNFY
110 120 130 140 150
GRKLNPIQGN PEKEQRVHLL AAQGYRWKRL RTISSQSFSN ASLKKMKRTV
160 170 180 190 200
EDSALELLRH IEKQTAGGEQ IDMLRFYQEY TMDVIGRFAM GQTDSMMFKN
210 220 230 240 250
PIVNVVREIF CGSRKNLMLI CQVFPPIGQF IRDLTFKFPR IPAFKLYSIM
260 270 280 290 300
QDVVAARIAQ REREKGAESG EPQDFIDLFL DARSDDVDFS AEAREDFSKR
310 320 330 340 350
NLKITKELSA DEVVGQCFLF LIGGFDTTAL SLSYVTYLLA VNPKIQEKVI
360 370 380 390 400
EEIAREFGTS EVEFEKLGRL KYMDCVIKEA LRLYPLASIS NSRKCMKTTT
410 420 430 440 450
VNGVKIEAGV YVQMDTWSLH YDPELWGEDV KEFKPERWST DEPLEHKGAY
460 470 480 490 500
LPFGLGPRQC IGMRLAIMEQ KILLTHLLKN YTFETGNKTR IPLKLVGSAT
510
TSPEDVFVHL RPRIW
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z48717 Genomic DNA Translation: CAA88607.1 |
PIRi | T24781 |
RefSeqi | NP_496109.1, NM_063708.3 |
Genome annotation databases
EnsemblMetazoai | T10B9.7.1; T10B9.7.1; WBGene00011676 |
GeneIDi | 188360 |
KEGGi | cel:CELE_T10B9.7 |
UCSCi | T10B9.7, c. elegans |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z48717 Genomic DNA Translation: CAA88607.1 |
PIRi | T24781 |
RefSeqi | NP_496109.1, NM_063708.3 |
3D structure databases
SMRi | Q27518 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 53027, 1 interactor |
DIPi | DIP-25672N |
STRINGi | 6239.T10B9.7 |
Proteomic databases
EPDi | Q27518 |
PaxDbi | Q27518 |
PeptideAtlasi | Q27518 |
Genome annotation databases
EnsemblMetazoai | T10B9.7.1; T10B9.7.1; WBGene00011676 |
GeneIDi | 188360 |
KEGGi | cel:CELE_T10B9.7 |
UCSCi | T10B9.7, c. elegans |
Organism-specific databases
CTDi | 188360 |
WormBasei | T10B9.7 ; CE01659 ; WBGene00011676 ; cyp-13A2 |
Phylogenomic databases
eggNOGi | KOG0158, Eukaryota |
HOGENOMi | CLU_001570_5_2_1 |
InParanoidi | Q27518 |
OMAi | NIYVTHI |
OrthoDBi | 786853at2759 |
PhylomeDBi | Q27518 |
Miscellaneous databases
PROi | PR:Q27518 |
Gene expression databases
Bgeei | WBGene00011676, Expressed in multi-cellular organism and 3 other tissues |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128, Cyt_P450 IPR017972, Cyt_P450_CS IPR002401, Cyt_P450_E_grp-I IPR036396, Cyt_P450_sf |
Pfami | View protein in Pfam PF00067, p450, 1 hit |
PRINTSi | PR00463, EP450I PR00385, P450 |
SUPFAMi | SSF48264, SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086, CYTOCHROME_P450, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | C13A2_CAEEL | |
Accessioni | Q27518Primary (citable) accession number: Q27518 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Caenorhabditis annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Caenorhabditis elegans
Caenorhabditis elegans: entries, gene names and cross-references to WormBase - SIMILARITY comments
Index of protein domains and families