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UniProtKB - Q27433 (MEC2_CAEEL)

Entry version 130 (23 Feb 2022)
Sequence version 1 (01 Nov 1996)
Previous versions | rss
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Protein

Mechanosensory protein 2

Gene

mec-2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity) (PubMed:12478294).

Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channel
Biological processIon transport, Potassium transport, Sodium transport, Transport
LigandPotassium, Sodium

Protein family/group databases

Transport Classification Database

More...TCDBi		1.A.6.2.2, the epithelial na(+) channel (enac) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mechanosensory protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mec-2Imported
ORF Names:F14D12.4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...WormBasei		F14D12.4a ; CE04393 ; WBGene00003166 ; mec-2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei115 – 135HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000940381 – 481Mechanosensory protein 2Add BLAST481

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q27433

PTM databases

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q27433

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		WBGene00003166, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q27433, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a non-voltage-gated amiloride-sensitive cation channel complex (also called the degenerin channel complex) composed of at least the mec-2, mec-4, mec-6 and mec-10 subunits; the complex mediates mechanotransduction in touch cells (PubMed:12478294).

Interacts with mec-6 and mec-4 (PubMed:12478294).

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		45759, 5 interactors

Database of interacting proteins

More...DIPi		DIP-61307N

Protein interaction database and analysis system

More...IntActi		Q27433, 1 interactor

STRING: functional protein association networks

More...STRINGi		6239.F14D12.4a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q27433

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 67DisorderedSequence analysisAdd BLAST67
Regioni80 – 104DisorderedSequence analysisAdd BLAST25
Regioni403 – 481DisorderedSequence analysisAdd BLAST79

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi84 – 104Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi423 – 446Polar residuesSequence analysisAdd BLAST24
Compositional biasi459 – 475Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the band 7/mec-2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2621, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01030000234614

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q27433

Database of Orthologous Groups

More...OrthoDBi		1062075at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q27433

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.479.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR043202, Band-7_stomatin-like
IPR001107, Band_7
IPR036013, Band_7/SPFH_dom_sf
IPR018080, Band_7/stomatin-like_CS
IPR001972, Stomatin_HflK_HflKC_fam

The PANTHER Classification System

More...PANTHERi		PTHR10264, PTHR10264, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01145, Band_7, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00721, STOMATIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00244, PHB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF117892, SSF117892, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01270, BAND_7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

Q27433-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSATMSSARN SVVSLSSNGS VKVETRLVSN ERSSSIQQEG AMLPSSSSKD 
        60         70         80         90        100
DDLLSTSSDE VENMATRTLQ QLEESTSIIS ANSDDDSVKK EKQAEKDVEK 
       110        120        130        140        150
GNGKEEKANI QNEFGVCGWI LTILSYLLIF FTLPISACMC IKVVQEYERA 
       160        170        180        190        200
VIFRLGRLMP GGAKGPGIFF IVPCIDTYRK VDLRVLSFEV PPQEILSKDS 
       210        220        230        240        250
VTVAVDAVVY FRISNATISV TNVEDAARST KLLAQTTLRN ILGTKTLAEM 
       260        270        280        290        300
LSDREAISHQ MQTTLDEATE PWGVKVERVE VKDVRLPVQL QRAMAAEAEA 
       310        320        330        340        350
AREARAKVIV AEGEQKASRA LKEAAEVIAE SPSALQLRYL QTLNSISAEK 
       360        370        380        390        400
NSTIIFPFPI DLLSAFLQRT PPKVEEPPSL PKKIRSCCLY KYPDWVQGMV 
       410        420        430        440        450
GSEGGGGHGH SHGGGGGGLG SSQGAFHPSQ AGSGPSTTTT SGRPLLRSMR 
       460        470        480 
EAQFHSAAPP ISAPNQSQTS VSQLDPALLI R
Length:481
Mass (Da):51,900
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37D2894AD39E040A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8MQ74Q8MQ74_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
392Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KZ92H2KZ92_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
317Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1DQJ7A0A3B1DQJ7_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
399Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1DVR7A0A3B1DVR7_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
1,180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1DVV1A0A3B1DVV1_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
1,172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1E057A0A3B1E057_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
1,239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1E3V6A0A3B1E3V6_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
422Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1E3Y0A0A3B1E3Y0_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
1,164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1E532A0A3B1E532_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
333Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B1E553A0A3B1E553_CAEEL
PHB domain-containing protein
mec-2 CELE_F14D12.4, F14D12.4
414Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U26736 Genomic DNA Translation: AAA87552.1
U26735 mRNA Translation: AAA87551.1
BX284606 Genomic DNA Translation: CCD83468.1

Protein sequence database of the Protein Information Resource

More...PIRi		S60260

NCBI Reference Sequences

More...RefSeqi		NP_741797.1, NM_171691.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		F14D12.4a.1; F14D12.4a.1; WBGene00003166

Database of genes from NCBI RefSeq genomes

More...GeneIDi		180826

UCSC genome browser

More...UCSCi		F14D12.4a, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U26736 Genomic DNA Translation: AAA87552.1
U26735 mRNA Translation: AAA87551.1
BX284606 Genomic DNA Translation: CCD83468.1
PIRiS60260
RefSeqiNP_741797.1, NM_171691.3

3D structure databases

SMRiQ27433
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi45759, 5 interactors
DIPiDIP-61307N
IntActiQ27433, 1 interactor
STRINGi6239.F14D12.4a

Protein family/group databases

TCDBi1.A.6.2.2, the epithelial na(+) channel (enac) family

PTM databases

SwissPalmiQ27433

Proteomic databases

PaxDbiQ27433

Genome annotation databases

EnsemblMetazoaiF14D12.4a.1; F14D12.4a.1; WBGene00003166
GeneIDi180826
UCSCiF14D12.4a, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		180826
WormBaseiF14D12.4a ; CE04393 ; WBGene00003166 ; mec-2

Phylogenomic databases

eggNOGiKOG2621, Eukaryota
GeneTreeiENSGT01030000234614
InParanoidiQ27433
OrthoDBi1062075at2759
PhylomeDBiQ27433

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q27433

Gene expression databases

BgeeiWBGene00003166, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues
ExpressionAtlasiQ27433, baseline and differential

Family and domain databases

Gene3Di3.30.479.30, 1 hit
InterProiView protein in InterPro
IPR043202, Band-7_stomatin-like
IPR001107, Band_7
IPR036013, Band_7/SPFH_dom_sf
IPR018080, Band_7/stomatin-like_CS
IPR001972, Stomatin_HflK_HflKC_fam
PANTHERiPTHR10264, PTHR10264, 1 hit
PfamiView protein in Pfam
PF01145, Band_7, 1 hit
PRINTSiPR00721, STOMATIN
SMARTiView protein in SMART
SM00244, PHB, 1 hit
SUPFAMiSSF117892, SSF117892, 1 hit
PROSITEiView protein in PROSITE
PS01270, BAND_7, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMEC2_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q27433
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: February 23, 2022
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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