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Entry version 161 (29 Sep 2021)
Sequence version 2 (19 Sep 2003)
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Protein

Protein tumorous imaginal discs, mitochondrial

Gene

l(2)tid

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a tumor suppressor in larval imaginal disks.

1 Publication

Miscellaneous

In strains Harvich and Apxo, there are 2 identical genes which code for l2tid protein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi227Zinc 1By similarity1
Metal bindingi230Zinc 1By similarity1
Metal bindingi244Zinc 2By similarity1
Metal bindingi247Zinc 2By similarity1
Metal bindingi266Zinc 2By similarity1
Metal bindingi269Zinc 2By similarity1
Metal bindingi280Zinc 1By similarity1
Metal bindingi283Zinc 1By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri214 – 292CR-typeAdd BLAST79

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone, Developmental protein
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein tumorous imaginal discs, mitochondrial
Alternative name(s):
Protein lethal(2)tumorous imaginal discs
TID50
TID56
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:l(2)tid
ORF Names:CG5504
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0002174, l(2)tid

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0002174

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – ?MitochondrionSequence analysis
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000007258? – 520Protein tumorous imaginal discs, mitochondrial

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q27237

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed throughout embryonic development. In larvae, expression is seen in sensory organs, gopplet cells, gonads, imaginal disks, proventriculus, fat body, hematopoietic organ, midgut, Malpighian tubules and ring gland.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout development, highest expression in first and second instar larvae and adults.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0002174, Expressed in testis and 45 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q27237, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q27237, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
71741, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q27237, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0088955

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q27237

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini65 – 130JAdd BLAST66
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati227 – 234CXXCXGXG motif; approximate8
Repeati244 – 251CXXCXGXG motif8
Repeati266 – 273CXXCXGXG motif; approximate8
Repeati280 – 287CXXCXGXG motif8

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni430 – 520DisorderedSequence analysisAdd BLAST91

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi476 – 494Basic and acidic residuesSequence analysisAdd BLAST19

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri214 – 292CR-typeAdd BLAST79

Keywords - Domaini

Repeat, Transit peptide, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0715, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155280

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q27237

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q27237

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06257, DnaJ, 1 hit
cd10719, DnaJ_zf, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.287.110, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01152, DnaJ, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012724, DnaJ
IPR002939, DnaJ_C
IPR001623, DnaJ_domain
IPR018253, DnaJ_domain_CS
IPR008971, HSP40/DnaJ_pept-bd
IPR001305, HSP_DnaJ_Cys-rich_dom
IPR036410, HSP_DnaJ_Cys-rich_dom_sf
IPR036869, J_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00226, DnaJ, 1 hit
PF01556, DnaJ_C, 1 hit
PF00684, DnaJ_CXXCXGXG, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00625, JDOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00271, DnaJ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46565, SSF46565, 1 hit
SSF49493, SSF49493, 1 hit
SSF57938, SSF57938, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00636, DNAJ_1, 1 hit
PS50076, DNAJ_2, 1 hit
PS51188, ZF_CR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform A (identifier: Q27237-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMISCKKLFV FRQLPAVRRC LAAAAFSTPR ATSYRILSSA GSGSTRADAP
60 70 80 90 100
QVRRLHTTRD LLAKDYYATL GVAKNANGKD IKKAYYQLAK KYHPDTNKED
110 120 130 140 150
PDAGRKFQEV SEAYEVLSDE QKRREYDTYG QTAENIGRQG GGFPGGGAGG
160 170 180 190 200
FGPEGFSQSW QFRSSIDPEE LFRKIFGEGN FRTNSFDDFA DSKFGFGQAQ
210 220 230 240 250
EMVMDLTFAQ AARGVNKDVN VNVVDQCPKC AGTKCEPGTK PGRCQYCNGT
260 270 280 290 300
GFETVSTGPF VMRSTCRYCQ GTRQHIKYPC SECEGKGRTV QRRKVTVPVP
310 320 330 340 350
AGIENGQTVR MQVGSKELFV TFRVERSDYF RREGADVHTD AAISLAQAVL
360 370 380 390 400
GGTVRVQGVY EDQWINVEPG TSSHHKIMLR GKGLKRVNAH GHGDHYVHVK
410 420 430 440 450
ITVPSAKKLD KKRLALIEAY AELEEDTPGQ IHGIANRKDG SKQATAGASE
460 470 480 490 500
EPGAGAAAKA SAAAAGSGAS KPGPGAEESE GKDQWTDNKK TKAKEGGGSG
510 520
SGQGDGGGGG FISKIKSMFN
Length:520
Mass (Da):56,137
Last modified:September 19, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1904B878F386FB1A
GO
Isoform B (identifier: Q27237-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     446-447: AG → SE
     448-520: Missing.

Show »
Length:447
Mass (Da):49,401
Checksum:iDA1ABE1C8A85570A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7KVH7Q7KVH7_DROME
Uncharacterized protein, isoform C
l(2)tid cDNA 10D, Dmel\CG5504, DnaJ, l(2)701, l(2)tud
507Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4K7M9A0A0B4K7M9_DROME
Uncharacterized protein, isoform D
l(2)tid cDNA 10D, Dmel\CG5504, DnaJ, l(2)701, l(2)tud
514Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3DN23D3DN23_DROME
GH23452p
l(2)tid-RA cDNA 10D, Dmel\CG5504, DnaJ, l(2)701, l(2)tid
445Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti286K → M (PubMed:9373138).Curated1
Sequence conflicti286K → M (PubMed:7758246).Curated1
Sequence conflicti286K → M in CAA64528 (Ref. 3) Curated1
Sequence conflicti286K → M (PubMed:12537569).Curated1
Sequence conflicti341A → V (PubMed:9373138).Curated1
Sequence conflicti341A → V (PubMed:7758246).Curated1
Sequence conflicti341A → V in CAA64528 (Ref. 3) Curated1
Sequence conflicti341A → V (PubMed:12537569).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti28T → A in strain: Apxo. 1
Natural varianti47 – 48Missing in strain: Oregon-2 and Oregon-R. 2
Natural varianti222N → I in strain: Apxo. 1
Natural varianti286 – 287Missing in strain: Apxo. 2
Natural varianti286K → R in strain: Oregon-2 and Oregon-R. 1
Natural varianti415A → D in strain: Apxo. 1
Natural varianti478E → K in strain: bIf and Berkeley. 1
Natural varianti489K → E in strain: bIf and Berkeley. 1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_008308446 – 447AG → SE in isoform B. 1 Publication2
Alternative sequenceiVSP_008309448 – 520Missing in isoform B. 1 PublicationAdd BLAST73

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X95241 Genomic DNA Translation: CAA64528.1
X95242 Genomic DNA Translation: CAA64531.1
X95247 Genomic DNA Translation: CAA64536.1
X95249 Genomic DNA Translation: CAA64538.1
X95251 Genomic DNA Translation: CAA64540.1
Y10074 Genomic DNA Translation: CAA71163.1
Y10074 Genomic DNA Translation: CAA71164.1
X77822 Genomic DNA Translation: CAA54837.1
X98094 Genomic DNA Translation: CAA66720.1
AE013599 Genomic DNA Translation: AAF47051.3
AE013599 Genomic DNA Translation: AAS64764.1
AY069853 mRNA Translation: AAL39998.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S42091

NCBI Reference Sequences

More...
RefSeqi
NP_524932.2, NM_080193.5 [Q27237-2]
NP_995932.1, NM_206210.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0089503; FBpp0088498; FBgn0002174 [Q27237-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
48844

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5504

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95241 Genomic DNA Translation: CAA64528.1
X95242 Genomic DNA Translation: CAA64531.1
X95247 Genomic DNA Translation: CAA64536.1
X95249 Genomic DNA Translation: CAA64538.1
X95251 Genomic DNA Translation: CAA64540.1
Y10074 Genomic DNA Translation: CAA71163.1
Y10074 Genomic DNA Translation: CAA71164.1
X77822 Genomic DNA Translation: CAA54837.1
X98094 Genomic DNA Translation: CAA66720.1
AE013599 Genomic DNA Translation: AAF47051.3
AE013599 Genomic DNA Translation: AAS64764.1
AY069853 mRNA Translation: AAL39998.1
PIRiS42091
RefSeqiNP_524932.2, NM_080193.5 [Q27237-2]
NP_995932.1, NM_206210.3

3D structure databases

SMRiQ27237
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi71741, 9 interactors
IntActiQ27237, 2 interactors
STRINGi7227.FBpp0088955

Proteomic databases

PaxDbiQ27237

Genome annotation databases

EnsemblMetazoaiFBtr0089503; FBpp0088498; FBgn0002174 [Q27237-2]
GeneIDi48844
KEGGidme:Dmel_CG5504

Organism-specific databases

FlyBaseiFBgn0002174, l(2)tid
VEuPathDBiVectorBase:FBgn0002174

Phylogenomic databases

eggNOGiKOG0715, Eukaryota
GeneTreeiENSGT00940000155280
InParanoidiQ27237
PhylomeDBiQ27237

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
48844, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
48844

Protein Ontology

More...
PROi
PR:Q27237

Gene expression databases

BgeeiFBgn0002174, Expressed in testis and 45 other tissues
ExpressionAtlasiQ27237, baseline and differential
GenevisibleiQ27237, DM

Family and domain databases

CDDicd06257, DnaJ, 1 hit
cd10719, DnaJ_zf, 1 hit
Gene3Di1.10.287.110, 1 hit
HAMAPiMF_01152, DnaJ, 1 hit
InterProiView protein in InterPro
IPR012724, DnaJ
IPR002939, DnaJ_C
IPR001623, DnaJ_domain
IPR018253, DnaJ_domain_CS
IPR008971, HSP40/DnaJ_pept-bd
IPR001305, HSP_DnaJ_Cys-rich_dom
IPR036410, HSP_DnaJ_Cys-rich_dom_sf
IPR036869, J_dom_sf
PfamiView protein in Pfam
PF00226, DnaJ, 1 hit
PF01556, DnaJ_C, 1 hit
PF00684, DnaJ_CXXCXGXG, 1 hit
PRINTSiPR00625, JDOMAIN
SMARTiView protein in SMART
SM00271, DnaJ, 1 hit
SUPFAMiSSF46565, SSF46565, 1 hit
SSF49493, SSF49493, 1 hit
SSF57938, SSF57938, 1 hit
PROSITEiView protein in PROSITE
PS00636, DNAJ_1, 1 hit
PS50076, DNAJ_2, 1 hit
PS51188, ZF_CR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTID_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q27237
Secondary accession number(s): O02528
, O02529, O02549, Q24554, Q27259, Q7KVH8, Q8T9A7, Q9W1K7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2003
Last sequence update: September 19, 2003
Last modified: September 29, 2021
This is version 161 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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