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UniProtKB - Q27198 (Q27198_TETTH)
Protein
Histone acetyltransferase
Gene
N/A
Organism
Tetrahymena thermophila
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 152 | Coenzyme ACombined sources | 1 |
GO - Molecular functioni
- histone acetyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- chromatin organization Source: UniProt
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | |
Organismi | Tetrahymena thermophilaImported |
Taxonomic identifieri | 5911 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Ciliophora › Intramacronucleata › Oligohymenophorea › Hymenostomatida › Tetrahymenina › Tetrahymenidae › Tetrahymena |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationStructurei
3D structure databases
SMRi | Q27198 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q27198 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 53 – 203 | N-acetyltransferaseInterPro annotationAdd BLAST | 151 | |
Domaini | 300 – 370 | BromoInterPro annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 126 – 128 | Coenzyme A bindingCombined sources | 3 | |
Regioni | 133 – 139 | Coenzyme A bindingCombined sources | 7 | |
Regioni | 164 – 171 | Coenzyme A bindingCombined sources | 8 | |
Regioni | 387 – 418 | DisorderedSequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 389 – 405 | Polar residuesSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Keywords - Domaini
BromodomainPROSITE-ProRule annotationFamily and domain databases
Gene3Di | 1.20.920.10, 1 hit |
IDEALi | IID50128 |
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR037800, GCN5 IPR000182, GNAT_dom |
PANTHERi | PTHR45750, PTHR45750, 1 hit |
Pfami | View protein in Pfam PF00583, Acetyltransf_1, 1 hit PF00439, Bromodomain, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit PS51186, GNAT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q27198-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADQEKSAQD AQNAAPQETA FVGMNGEETG LGFATRDQGA KVEEDQGLLD
60 70 80 90 100
FDILTNDGTH RNMKLLIDLK NIFSRQLPKM PKEYIVKLVL DRHHESMVIL
110 120 130 140 150
KNKQKVIGGI CFRQYKPQRF AEVAFLAVTA NEQVRGYGTR LMNKFKDHMQ
160 170 180 190 200
KQNIEYLLTY ADNFAIGYFK KQGFTKEHRM PQEKWKGYIK DYDGGTLMEC
210 220 230 240 250
YIHPYVDYGN ISQIIKRQKE LLIERIKKLS LNEKVFSGKE YAALIQNSMD
260 270 280 290 300
NEDPENPKVN PSDIPGVAFS GWEWKDYHEL KKSKERSFNL QCANVIENMK
310 320 330 340 350
RHKQSWPFLD PVNKDDVPDY YDVITDPIDI KAIEKKLQNN QYVDKDQFIK
360 370 380 390 400
DVKRIFTNAK IYNQPDTIYY KAAKELEDFV EPYLTKLKDT KESNTPSNNN
410
SAHGSKKPLP VRKSIKKK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U47321 mRNA Translation: AAB01099.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U47321 mRNA Translation: AAB01099.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1M1D | X-ray | 2.20 | A/C | 48-209 | [»] | |
1PU9 | X-ray | 2.30 | A | 48-209 | [»] | |
1PUA | X-ray | 2.30 | A | 48-209 | [»] | |
1Q2C | X-ray | 2.25 | A | 49-209 | [»] | |
1Q2D | X-ray | 2.25 | A | 49-209 | [»] | |
1QSN | X-ray | 2.20 | A | 49-209 | [»] | |
1QSR | X-ray | 2.00 | A | 49-209 | [»] | |
1QST | X-ray | 1.70 | A | 49-208 | [»] | |
5GCN | NMR | - | A | 46-210 | [»] | |
SMRi | Q27198 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q27198 |
Family and domain databases
Gene3Di | 1.20.920.10, 1 hit |
IDEALi | IID50128 |
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR037800, GCN5 IPR000182, GNAT_dom |
PANTHERi | PTHR45750, PTHR45750, 1 hit |
Pfami | View protein in Pfam PF00583, Acetyltransf_1, 1 hit PF00439, Bromodomain, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 1 hit |
SUPFAMi | SSF47370, SSF47370, 1 hit SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 1 hit PS50014, BROMODOMAIN_2, 1 hit PS51186, GNAT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q27198_TETTH | |
Accessioni | Q27198Primary (citable) accession number: Q27198 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | January 19, 2022 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |