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Protein
Submitted name:

Trans-sialidase

Gene
N/A
Organism
Trypanosoma cruzi
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SABIO-RKiQ26966

Protein family/group databases

CAZyiGH33 Glycoside Hydrolase Family 33

Names & Taxonomyi

Protein namesi
Submitted name:
Trans-sialidaseImported
OrganismiTrypanosoma cruziImported
Taxonomic identifieri5693 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5126
DrugBankiDB03296 Lactose Sialic Acid
DB01768 Methylumbelliferyl Sialic Acid

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi397 ↔ 411Combined sources

Interactioni

Chemistry databases

BindingDBiQ26966

Structurei

3D structure databases

ProteinModelPortaliQ26966
SMRiQ26966
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ26966

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 358SialidaseInterPro annotationAdd BLAST321

Phylogenomic databases

eggNOGiENOG410JQ15 Eukaryota
COG4409 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR011040 Sialidase
IPR026856 Sialidase_fam
IPR036278 Sialidase_sf
IPR008377 Sialidase_trypan
PANTHERiPTHR10628 PTHR10628, 1 hit
PfamiView protein in Pfam
PF13859 BNR_3, 1 hit
PRINTSiPR01803 TCSIALIDASE
SUPFAMiSSF49899 SSF49899, 1 hit
SSF50939 SSF50939, 1 hit

Sequencei

Sequence statusi: Complete.

Q26966-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLAPGSSRVE LFKRQSSKVP FEKDGKVTER VVHSFRLPAL VNVDGVMVAI
60 70 80 90 100
ADARYETSND NSLIDTVAKY SVDDGETWET QIAIKNSRAS SVSRVVDPTV
110 120 130 140 150
IVKGNKLYVL VGSYNSSRSY WTSHGDARDW DILLAVGEVT KSTAGGKITA
160 170 180 190 200
SIKWGSPVSL KEFFPAEMEG MHTNQFLGGA GVAIVASNGN LVYPVQVTNK
210 220 230 240 250
KKQVFSKIFY SEDEGKTWKF GKGRSAFGCS EPVALEWEGK LIINTRVDYR
260 270 280 290 300
RRLVYESSDM GNSWLEAVGT LSRVWGPSPK SNQPGSQSSF TAVTIEGMRV
310 320 330 340 350
MLFTHPLNFK GRWLRDRLNL WLTDNQRIYN VGQVSIGDEN SAYSSVLYKD
360 370 380 390 400
DKLYCLHEIN SNEVYSLVFA RLVGELRIIK SVLQSWKNWD SHLSSICTPA
410 420 430 440 450
DPAASSSERG CGPAVTTVGL VGFLSHSATK TEWEDAYRCV NASTANAERV
460 470 480 490 500
PNGLKFAGVG GGALWPVSQQ GQNQRYRFAN HAFTVVASVT IHEVPSVASP
510 520 530 540 550
LLGASLDSSG GKKLLGLSYD ERHQWQPIYG STPVTPTGSW EMGKRYHVVL
560 570 580 590 600
TMANKIGSEY IDGEPLEGSG QTVVPDERTP DISHFYVGGY KRSDMPTISH
610 620 630 640
VTVNNVLLYN RQLNAEEIRT LFLSQDLIGT EAHMDSSSDT SA
Length:642
Mass (Da):70,593
Last modified:November 1, 1996 - v1
Checksum:i65BD95DD7ADBC222
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26499 Genomic DNA Translation: AAA66352.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26499 Genomic DNA Translation: AAA66352.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MR5X-ray2.25A2-635[»]
1MS0X-ray2.50A/B2-635[»]
1MS1X-ray1.80A/B2-635[»]
1MS3X-ray1.65A/B2-635[»]
1MS4X-ray2.21A/B2-635[»]
1MS5X-ray2.00A/B2-635[»]
1MS8X-ray2.00A/B2-635[»]
1MS9X-ray1.58A/B2-635[»]
1S0IX-ray1.60A2-635[»]
1S0JX-ray1.65A2-635[»]
2AH2X-ray1.60A2-635[»]
3OPZX-ray3.40A/B/C2-635[»]
3PJQX-ray2.10A2-635[»]
ProteinModelPortaliQ26966
SMRiQ26966
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiQ26966
ChEMBLiCHEMBL5126
DrugBankiDB03296 Lactose Sialic Acid
DB01768 Methylumbelliferyl Sialic Acid

Protein family/group databases

CAZyiGH33 Glycoside Hydrolase Family 33

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410JQ15 Eukaryota
COG4409 LUCA

Enzyme and pathway databases

SABIO-RKiQ26966

Miscellaneous databases

EvolutionaryTraceiQ26966

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR011040 Sialidase
IPR026856 Sialidase_fam
IPR036278 Sialidase_sf
IPR008377 Sialidase_trypan
PANTHERiPTHR10628 PTHR10628, 1 hit
PfamiView protein in Pfam
PF13859 BNR_3, 1 hit
PRINTSiPR01803 TCSIALIDASE
SUPFAMiSSF49899 SSF49899, 1 hit
SSF50939 SSF50939, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ26966_TRYCR
AccessioniPrimary (citable) accession number: Q26966
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 10, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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